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1、参考文献CaoY.W.C.,JinR.C.,MirkinC.A.,NanoparticleswithRamanspectroscopicfingerprintsfor DNA and RNA detectionJ, Science, 2002, 297: 15361540Li H.X., Rothberg L.J., Label-free colorimetric detection of specific sequences in genomic DNAamplified bythe polymerase chain reactionJ, J.Am. Chem. Soc., 2004, 12

2、6:1095810961Pavlov V., Shlyahovsky B., Willner I., Fluorescence detection of DNA by the catalytic activation of an aptamer/thrombin complexJ, J. Am. Chem. Soc., 2005, 127: 65226523Ho H.A., Dore K., Boissinot M., et al. Direct molecular detection of nucleic acids by fluorescence signal amplificationJ

3、, J. Am. Chem. Soc., 2005, 127: 1267312676PengH.,ZhangL.,KjallmanT.H.M.,etal.DNAhybridizationdetectionwithblue luminescent quantumdotsand dye-labeled single-stranded DNAJ, J.Am. Chem.Soc., 2007,129:30483049MiaoW.,BardA.J.,Electrogeneratedchemiluminescence.DNAhybridizationdetectionathigh amplificatio

4、n with Ru(bpy)32+-containing microspheresJ,. Chem., 2004, 76: 53795386Zhang S.S., Xia J.P, Li X.M., Electrochemical biosensor for detection of adenosine based structure-switching aptamer and amplification with reporter probe DNA modified Au . Chem., 2008, 80: 83828388Zhang S.S., Zhong H., Ding C.F.,

5、 Ultrasensitive flow injection chemiluminescence detection of DNAhybridizationusingsignalDNAprobe modifiedwithAuandCuS nanoparticlesJ, .Chem.,2008,80:Fan, A.; Lau, C.; Lu, J. Magnetic Bead-Based Chemiluminescent Metal Immunoassay with a Colloidal Gold Label, . Chem., 2005, 77, 32383242Polsky, R.; Gi

6、ll, R.; Kaganovsky, L.NucleicAcid-Functionalized Pt Nanoparticles: Catalytic Labels for the Amplified Electrochemical Detection of Biomolecules, . Chem., 2006, 78, Yehezkeli, O.; Raichlin, S.; -Vered, R. et al., Biocatalytic Implant of Pt Nanoclusters into GlucoseOxidase:AMethod toElectricallyWire t

7、he Enzyme andtoTransformIt fromanOxidase to a Hydrogenase, J. Phys. Chem. Lett., 2010, 1, 28162819Bi, S.; Yan, Y.; Hao, S. Colorimetric Logic Gates Based on Supramolecular DNAzyme Structures, Angew. Chem. Int. Ed., 2010, 49, 44384442L. J. Kricka, P. E. Stanley. Bioluminescence and Chemiluminescence

8、Literature. Journal of Bioluminescence and ChemiluminescenceJ. 1996, 11 (2): 107122Raman C V, Krishman K S. A new type of secondary radiationJ. Nature, 1928, 121 (3048): Fleis ann M, Hendra P J, McQuillan A. Raman spectra of pyridine adsorbed at a silver electrodeJ. Chemical Physics Letters, 1974, 2

9、6 (2): 163166Jeanmaire D L,Van Duyne R P. Surface Raman spectroelectrochemistry Part I. Heterocyclic, aromatic, and aliphatic amines adsorbed on the anodized silver electrodeJ. Journal of Electro ytical Chemistry, 1977, 84 (1): 120Albrecht M G, Creighton J A. Anomalously intense Raman spectra of pyr

10、idine at a silver electrodeJ. Journal of the American Chemical Society, 1977, 99 (15): 52155217Tuan Vo-Dinh. Surface-enhanced Raman spectroscopy using metallic Trendsin yticalchemistry,1998,17(8):Peng Y. G., Zhang D. D., Li Y. et al., Label-free and sensitive faradic impedance aptasensor for the det

11、ermination of lysozyme based on -induced aptamer displacementJ, Biosensors Bioelectronics, 2009, 25, 9499,英,纳米金标记p53 抗体探针在p53 蛋白检测中的应用J,中国实验学,2010 , 14 (6), 6Hu K.C., LanD.X.,Li X.M.,Electrochemical DNABiosensorBased on NanoporousGold Electrode and Multifunctional Encoded DNA Au Bio Bar CodesJ. Chem

12、, 2008, 80 (23): Doering W E, Nie S. Spectroscopic tags using dye-embedded nanoparticles and surface-enhanced Raman scatteringJ. ytical Chemistry, 2003, 75 (22): 61716176Wang L. Q., Li L. Y., Xu Y. et al., Simultaneously fluorescence detecting thrombin and lysozyme based on magnetic nanoparticle con

13、densationJ, Talanta, 2009, 79, 557561,李吉祥,静,表面增强拉曼光谱在中的应用J,光谱,2010,27 (1), 1Su X, Zhang J, Berlin A A, et al. Composite anic-inanic nanoparticles (COINs) with chemically encoded optical signaturesJ. Nano Letters, 2005, 5 (1): 4954Lee S, Kim S, Choo J. Biological Imaging of HEK293 Cells Expressing PL

14、C-1 Using Surface-Enhanced Raman MicroscopyJ, ytical Chemistry, 2007, 79 (3): 916922Qian X, Peng X H, Nie S, et al. In vivo tumor ing and spectroscopic detection with surface-enhanced Raman nanoparticle tagsJ, Nature Biotechnology, 2008, 26 (1): 8390Hu K. C., Lan D. X., Li X. M., Electrochemical DNA

15、 Biosensor Based on Nanoporous Gold Electrode and Multifunctional Encoded DNA Au Bio Bar CodesJ. . Chem, 2008, 80 (23): Huang H. P., Jie G. F., Cui R. J. et al., DNA aptamer-based detection of lysozyme by an electrochemiluminescence assay coupled to quantum dotsJ, Electrochemistry Communications, 20

16、09, 11, 816818Porter M D, Lipert R J, Siperko L M, et al. SERS as a bioassay platform: fundamentals, design, and applicationsJ. Chemical Society Reviews. 2008, 37 (5): 10011011Erdem A., Karadeniz H., Mayer G. et al., Electrochemical sensing of aptamer-protein interactions using a magnetic particle assay and single-use sensor technologyJ, Electro ysis, 2009, 21, 12781284Rodrguez M. C., Rivas G. A., Label-free e

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