雨课堂学堂在线学堂云《Oral Tissue Regeneration》单元测试考核答案

注：不含主观题第1题单选题(10分)Architectureofthescaffoldhastomimicthescaleofthe(),creatinganartificialmicroenvironment.AcellmorphologyBextracellularmatrixCcellmigrationDcellcytoplasm第2题判断题(10分)Topographyofthescaffoldsregulatesthebehaviorofthecells.第3题多选题(10分)()canbeusedasscaffoldsintissueengineering.AcalciumphosphatesandbioactiveglassesBmetalorganicandhybridsCcompositematerialsDnanoparticles正确答案：ABCD第4题判断题(10分)Oraltissueshaveastrongabilitytoregeneratewhentheoriginaltissueintegrityhasbeenseverelydamaged.第5题填空题(10分)Thecellsusedfororaltissueregenerationare____.正确答案：:["mesenchymalstemcells"]第6题单选题(10分)Mesenchymalstemcellswerefirstisolatedfrom()AbonemarrowBtoothpulpCperiodontalligamentDgingivalconnectivetissue第7题多选题(10分)Theadvantagesoforalmesenchymalstemcellsoverbone-marrowderivedmesenchymalstemcellsinoraltissueregenerationinclude().AeasyaccessBlesstraumaticinterventionsChighpotentialtoregenerateintraoraltissuesDlowerimmunogenecity正确答案：ABC第8题多选题(10分)Thebonemarrowbiopsyformesenchymalstemcellisolationalsoinclude().AhematopoieticprogenitorcellsBbloodcellsCendothelialprogenitorcellsDplatelets正确答案：ABCD第9题单选题(10分)()arethemostcriticalcomponentintissueengineeringandregenerativemedicine.AscaffoldsBsignalmoleculesCcellsDvessels第10题判断题(10分)Oraltissueshaborstemcells.课后作业第1题多选题(3.5分)Itisextremelydifficulttoregeneratedamagedtoothstructuresbecause().Ainthetooth,thenumberofstemcellswithahighregenerativecapacityislimitedBdentaltissuesarehighlymineralizedCthepulpchamberbecomessmallerwithageorcalcificationofthepulpDtheenamelformingameloblastsarenolongerpresentaftertootheruption正确答案：ACD第2题多选题(3.5分)Theconceptualtriadoftissueengineeringincludes().AessentialnutrientsBregenerativecellsCsupportingscaffoldsDbioactivemolecules正确答案：BCD第3题判断题(3分)Thescaffoldsappliedintissueengineeringshouldmimicthecharacteristicsofthetargettissueinbiologicalactivity,mechanicalintegrityandfunctionality.第4题多选题(3.5分)Bioactivemoleculesappliedintissuenengineeringinclude().AgrowthfactorsBtranscriptionfactorsCessentialaminoacidsDsynthesizedchemicalswhichcanorchestratetissuehealing正确答案：ABD第5题判断题(3分)Theenamelorganandthedentalfolliclearebothderivedfromtheectoderm.第6题多选题(3.5分)Enamelisthehardesttissueinthebodybecause().Afullyformedenameliscomposedofapproximately96%inorganicmineralsBtheprismsandtheinterprismaticsubstancearehighlyorganizedCtheenamelisderivedfromtheectodermDtheenameliscomposedofhydroxyapatite正确答案：AB第7题判断题(3分)Thecellprocessesoftheodontoblastssynthesizeglycoproteins,whichweretransportedtothecellbodiesandthensecretedtoformthepredentinmatrix.第8题单选题(3.5分)()isformedfromapre-existingodontoblastinresponsetoamildstimulus.APrimarydentinBSecondarydentinCReactionarydentinDReparativedentin第9题判断题(3分)Terminaldifferentiationofthecellsusuallycoincideswithincreasedproliferationrate.第10题单选题(3.5分)Theconversionofonematurecellularphenotypetoanotherisreferredtoas().AdedifferentiationBredifferentiationCtransdifferentiationDsecondarydifferentiation第11题判断题(3分)Ameloblastinisanameloblastspecificprotein,andcanbeusedasamarkerforameloblastdifferentiation.第12题单选题(3.5分)Ingeneral,enamelrodsruninaperpendiculardirectiontotheenamelsurface,andinter-rodenamelisatanangleofapproximately()totheenamelrods.A45°B60°C90°D135°第13题填空题(3分)Analysesindicatedthata

____monthrecallisprobablytheminimaltimetojudgeradiographicevidenceofrootdevelopmentinclinicalrevascularizationcases.正确答案：:["12-18"]第14题填空题(3分)Inclinicalendodonticrevascularizationcases,thenumberofappointmentsisatleast____.正确答案：:["2"]第15题多选题(3.5分)Themainmethodsofregenerativeendodonticinclude().ApulprevascularizationBcellhomingCstemcelltransplantationDcelldifferentiation正确答案：ABCD第16题判断题(3分)Currently,pulprevascularizationandstemcelltransplantationhavebeenappliedclinically,whilecellhominghasnotbeenappliedinclinicalpractice.第17题填空题(3分)____andapexificationarethetreatmentmodalitiesforanimmaturetoothwithpulpnecrosisandapicalperiodontitis.正确答案：:["Regenerativeendodontics"]第18题多选题(3.5分)Basedontheirabilitytodifferentiate,thestemcellscanbedividedinto()stemcells.AomnipotentBtotipotentCpluripotentDmultipotent正确答案：BCD第19题单选题(3.5分)Forcedexpressionoffourtranscriptionfactorsinmurinefibroblastscanreprogramthesesomaticcellsto().AembryonicstemcellsBmesenchymalstemcellsCadultstemcellsDinducedpluripotentstemcells第20题多选题(3.5分)Dentalpulpstemcellscanbeisolatedusing().AenzymaticdigestionBsuspensioncultureCexplantmethodDco-culturewithepithelialcells正确答案：AC第21题多选题(3.5分)Comparedwiththetraditionalapexification,pulprevascularizationhastheadvantagesof().AinducingrootdevelopmentBapicalforamenclosureCrootcanalwallthickeningDcementumformation正确答案：ABC第22题判断题(3分)ESEadvocatesthatintheabsenceofstrongevidence,theuseoftraditionalCa(OH)2intracanalmedicationinpulpregenerationtreatmentshouldbeavoided,andtheantibioticsisrecommended.第23题多选题(3.5分)Themorphologicstagesoftoothdevelopmentinclude().AbudstageBcapstageCcrownstageDbellstage正确答案：ABD第24题判断题(3分)toothdevelopmentisregulatedbyaseriesofreciprocalinteractionsinvolvingbothectodermalandmesenchymalstemcells.第25题多选题(3.5分)Theapproachesofpulpregenerationinclude().AregeneratinganentiretoothBregenerationgperiodontaltissueCregeneratingafunctionalpulp-dentincomplexDregenerationalveolarbone正确答案：AC第26题多选题(3.5分)Thestructureofdentalpulpinclude().AodontoblastlayerBcell-poorzoneCcell-richzoneDpulpproper正确答案：ABCD第27题单选题(3.5分)Mostcommonly,theculturemediumissupplementedwitha()concentrationoffetalbovineserum(FBS)forbothisolationandexpansionofdentalpulpstemcells.A1-5%B5-10%C10-20%D20-40%第28题单选题(3.5分)()isrecommendedforneurogenicdifferentiationofdentalpulpstemcells.ASerum-freeculturemediumBSerum-richculturemediumCSphere-formingcultureDCo-culturesystems第29题多选题(3.5分)Cellco-culturesystemsinclude().Adirectcellco-cultureBorgancultureCtranswellsystemDtheuseofconditionedmedium正确答案：ACD第30题判断题(3分)Thedentalpulpisanendorganwithabundant

collateralcirculation.课后作业第1题判断题(3分)Evenunderbasalconditionswithoutanystimulationtowarddifferentiation,osteogenicandchondrogenicmarkersarestilldemonstratedbySHEDs.第2题多选题(3.5分)Exfoliatedteethmaybeanunexpecteduniqueresourceforstem-celltherapiesbecause().AStemcellsfromhumanexfoliateddeciduousteeth(SHED)arecapableofdifferentiatingintomultilineageprogenies.BStemcellsfromhumanexfoliateddeciduousteeth(SHED)havebetterdifferentiationcapabilityinosteogenesisandadipogenesisthanDPSCs.CStemcellsfromhumanexfoliateddeciduousteeth(SHED)canbeisolatedfromexfoliatedprimaryteeth.DStemcellsfromhumanexfoliateddeciduousteeth(SHED)possessedstem-cellcharacteristics.正确答案：ABCD第3题判断题(3分)Stemcellsfromhumanexfoliateddeciduousteeth(SHED)candifferentiateintofunctionalneuronsinvivo.第4题判断题(3分)SHEDexpressedstrongerpluripotentmarker,OCT-4,Nanog,andSox-2,comparedtoDPSC.第5题多选题(3.5分)Gingivalmesenchymalstemcells(GMSC)andtheirderivativecell-freeproductsexertpotentregenerativeandtherapeuticpotentialsin().AskindisorderBautoimmuneandinflammatorydiseaseCoralandmaxillofacialdisorderDnerveregeneration正确答案：ABCD第6题单选题(3.5分)()arerelativelyresistanttoirradiationorchronicperiapicalinflammationthanotherdentalMSCs,AGingivalmesenchymalstemcells(GMSC)BStemcellsfromtheapicalpapilla(SCAP)CStemcellsfromhumanexfoliateddeciduousteeth(SHED)Ddentalpulpstemcells(DPSC)第7题判断题(3分)Dentinmatrixacidicphosphoprotein1(DMP1)ishighlyexpressedindentalfolliclestemcells(DFSC).第8题单选题(3.5分)CD24,anothermarkerforthepluripotentpopulation,isregardedasarepresentativesurfacemarkerfor().APeriodontalligamnetstemcells(PDLSC)BGingivalmesenchymalstemcells(GMSC)CStemcellsfromtheapicalpapilla(SCAP)DStemcellsfromhumanexfoliateddeciduousteeth(SHED)第9题多选题(3.5分)Sub-populationofstemcellsfromtheapicalpapilla(SCAP)areableto().Aexpressneuronalcell-associatedmarkersBsecretesomeneurotrophic,neuroprotectivefactorsChaveangiogenicfunctionDhavelongertelomerelength正确答案：ABCD第10题多选题(3.5分)Therationalefortheapplicationofgrowthfactorstotheperiodontaldefectisbasedontheirabilityto().AstimulatecellproliferationBpromotecelldifferentiationCincreaseapoptosisDinfluencekeycellularfunctions正确答案：ABD第11题填空题(3分)____aretemporarilydepositedontothedentinalrootsurfaceandprovideaninitialandessentialstepintheformationofacellularcementum.正确答案：:["Enamelmatrixproteins"]第12题单选题(3.5分)Themajorfractionoftheenamelmatrixproteinsis().AenamelinsBamelogeninsCtuftelinDtuftproteins第13题判断题(3分)Intheabsenceofmineralizationenhancerβ-glycerophosphateanddexamethasone,enamelmatrixproteins(EMPs)cannotresultinasignificantlyhighernumberofvonKossastainedclonesofPDLSC.第14题多选题(3.5分)Enamelmatrixproteins(EMPs)areableto().ApromotePDLcellproliferationBincreasePDLcellattachmentCpromoteepithelialcellproliferationDincreasePDLcellmetabolism正确答案：ABD第15题单选题(3分)()favoursmesenchymalcellgrowthoverepithelium.AEnamelmatrixderivatives(EMD)Bbonemorphogenicproteins(BMPs)Cvascularendothelialgrowthfactor(vEGF)Dplatelet-derivedgrowthfactor(PDGF)第16题多选题(3.5分)Platelet-derivedgrowthfactor(PDGF)playsanimportantroleinarangeofbiologicalevents,evidencedby().APDGFisanextraordinarilypotentmitogenformostmesenchymalderivedconnective-tissue-formingcells.BPDGFpromoteproliferationoffibroblasts,smoothmuscle,orglialcells.CPDGFischemotactic.DPDGFinducesincreasedsynthesisofRNAandproteininconnective-tissue-formingcells.正确答案：ABCD第17题多选题(3.5分)Gingivalconnectivetissues,periodontalligamentandregeneratedtissuespositivelyexpress().APDGFbeta-receptorBPDGFalphareceptorCTGF-betareceptorIDTGF-betareceptorII正确答案：ACD第18题多选题(3.5分)Forthedescriptionofperiodontalregeneration,thecorrectare().APeriodontalregenerationisdefinedasthereproductionorreconstitutionofalostorinjuredpart.BPeriodontalregenerationrequiresnewattachmenttotherootsurface.CPeriodontalregenerationinvolvestheregenerationofprincipalfibres,butnotnecessarytheinsertionofthesefibresintonewlyformedcementumonarootsurface.DPeriodontalregenerationistheultimategoalofperiodontaltreatment.正确答案：ABD第19题填空题(3分)Ifepithelialcellspopulatefirst,theyrapidlyestablishcoverageoftheexposedrootsurface,forminga____.正确答案：:["longjunctionalepithelium"]第20题单选题(3.5分)Ifgingivalconnectivetissuecellsrepopulatetherootsurfaceafterperiodontalsurgeryfirst,().AnewcementummayformBrootsurfaceankylosismayoccurCnewconnectivetissueattachmentmayformDrootresorptionmayoccur第21题多选题(3.5分)Forasuccessfuloutcomeinperiodontalboneregeneration()mustbeconsidered.AtheremovalofthejunctionalandpocketepitheliumBthepreventionofepithelialcellmigrationintothehealingareaCclotstabilizationDspacecreation正确答案：ABCD第22题多选题(3.5分)GTRconsistsofplacingdifferenttypeofmembraneasthebarriertocover().AtheboneBthegingivalepitheliumCtheperiodontalligamentDthegingivalconnectivetissue正确答案：AC第23题多选题(3.5分)Membranederivedfrom()belongstoresorbablemembrane.AcollagentypeIBpolylacticacid(PLA)Cpolyglycolicacid(PGA)De-PTFE正确答案：ABC第24题判断题(3分)Highspeedcentrifugationwastophaseseparatethelayersbetweentheredcorpusclebaseandtheoverlayingclearliquidcontainingplasma.第25题多选题(3.5分)Cellsthataretrappedwithinthethree-dimensionalfibrinmatrixinclude().AplateletsBleukocytesCmacrophagesDgranulocytes正确答案：ABCD第26题多选题(3.5分)PRFservesimportantcriteriafortissueregenerationincluding().Aservingasathree-dimensionalfibrinscaffoldBservingasareservoirofnaturalgrowthfactorsCcontainingautologouscellssuchasleukocytes,macrophages,neutrophils,andplateletsDreleasinggrowthfactorsovera1to3-dayperiod.正确答案：ABC第27题填空题(3分)ModificationofthepreparationprotocolofPRFbyreducingtheappliedRCFto208gresultedin____.正确答案：:["theadvancedsolidPRF(A-PRF)"]第28题多选题(3.5分)Asuitablescaffoldshouldpossess().Aa3DandhighlyporousinterconnectedporenetworkBsurfacepropertiesareoptimizedforcellattachmentanddifferentiationCenableflowtransportofnutrientsDonsetofdegradationoccurswiththetissueregeneration正确答案：ABC第29题多选题(3.5分)Syntheticscaffoldsare().Aβ-tricalciumphosphateBpolyglycolicacidCchitosanDpolycarpolactone正确答案：ABD第30题多选题(3.5分)Multiphasicscaffoldsareexpectedtoperformvariousfunctionsincluding().AsupportingcellcolonizationBprovidingsufficientinitialmechanicalstrengthCincreasingcellmigration,growth,anddifferentiationDimpartingbiomimeticfunctionalitytotissue-engineeredboneandsofttissuegrafts正确答案：ABCD课后作业第1题单选题(4分)Thetoothanditssurroundingattachmenttissues–（）,theperiodontalligamentandthebundlebone–establishafunctionalunit.AtherootcementumBtherootCthecrownDtheenamal第2题判断题(4分)itiswelldocumentedthatfollowingmultipletoothextractionsandthesubsequentrestorationwithremovabledentures,thesizeofthealveolarridgewillbecomemarkedlyregenerated,notonlyinthehorizontalbutalsointheverticaldimension.第3题单选题(4分)followingtheremovalofsingleteeth,the（）partofthealveolarridgewillbemarkedlydiminished.AmesialBbuccalsideClingualsideD

palatalside第4题判断题(4分)Resorptionappearstobemorepronouncedatthebuccalthanatlingualorpalatalaspectsoftheridge.第5题判断题(4分)Class1andclass2ofthebonequalitycharacterizedalocationinwhichthewalls–thecorticalplates–ofthesitearethickandthevolumeofbonemarrowissmall.第6题单选题(4分)class3andclass4ofthebonequalityareborderedbyrelativelythinwallsof()bone.AmarrowBcorticalandmarrowCcorticalDwhole第7题判断题(4分)thedefinitionofosseointegrationwas“aindirectfunctionalandstructuralconnectionbetweenlivingboneandthesurfaceofaloadcarryingimplant”.第8题单选题(4分)Formationsofnewlyformedbonecouldberecognizedalreadyduringthefirstweekofhealing;thenewlyformedwovenboneprojectedfromthelateralwallofthecutbonybedbutdenovoformationofnewbonecouldalsobeseenontheimplantsurface，thisissocalled（）.AosteogenesisBboneremodelingCboneregenerationDcontactosteogenesis第9题单选题(4分)Theradiographicexaminationwillprovidemoredetailedinformationonthe()and()oftheboneavailableattherecipientsite.AqualityBamountCqualityandamountDnoneistrue第10题判断题(4分)Ifpossibleanimplantshouldbeplacedintoothposition,bothinamesio-distalandinabucco-lingualdirection.第11题单选题(4分)thestartingpointfortheinsertionoftheimplantinthebonemustbelocatedtowardsthebuccalsideofthecrestinthemandible,andtowardsthe()inthemaxilla.AbuccalBpalateCmesialDitdoesnotmatter第12题单选题(4分)Incasesofpartialedentulism,therecipientsiteclosesttoatoothmustfirstbeidentified.Thecylindrical

canalintherecipientsiteispreparedapproximately()awayfromtheprominenceofthetooth.A3.5–4mmB1-1.5mmC3-3.5mmD2-2.5mm第13题判断题(4分)theimplantsshouldbeplacedinatripodpositioninsteadofbeinginsertedinastraightline,therebyminimizingthetransmissionofbendingforcesontoeachindividualimplant第14题判断题(4分)Ifpossibletheimplantsshouldbeplacedintoothposition.Thismeansthatinthenormalcasethelongaxisoftheimplantshouldbedirectedthroughtheocclusalsurfaceofthefinalrestoration.第15题判断题(4分)Regardingthebucco-lingualdimension,thelongaxisofmandibularimplantswillmainlybedirectedtowardsthelimbuspartoftheincisorsorthepalatalcuspsoftheteethinthemaxilla.第16题判断题(4分)Afterthepositionoftheimplanthasbeenidentified,thedirectionorinclinationoftheimplantinthejaw，bucco-lingualandmesio-distal，mustbedetermined.第17题判断题(4分)Forimplantsplacedinthemaxilla,thecorrespondinginclinationshouldbetowardstheincisaledgesofthefrontalteethorthebuccalcuspsofthepremolarsormolarsofthemandible.第18题判断题(4分)Ifthestartingpointoftheimplantsitesinthemaxillaislocatedclosetothetopofthecrest,andifaconcavity凹onthebuccalsideoftheridgeispresent,thereisariskthatthesurgeonleansthelongaxisoftheimplantstoofarbuccally.第19题判断题(4分)Inextremelyresorbedmandibles,themostdistalimplantthatisplacedimmediatelyinfrontofthementalforamen,canbetilteddistallyinordertoachieveoptimalspreadingofthesupportingunits.第20题判断题(4分)Peri-implantdiseasemeansInflammatoryprocessesinthetissuessurroundinganimplant.第21题判断题(4分)Peri-implantmucositismeansReversibleinflammatoryprocessinthesofttissuessurroundingafunctioningimplant.第22题判断题(4分)Peri-implantitismeansInflammatoryprocessadditionallycharacterizedbylossofperi-implantbone.第23题判断题(4分)Themucosasurroundingimplantsandthegingivasurroundingteethhasnofeatureincommon.第24题判断题(4分)Theclinicalfeaturesofperi-implantmucositisareinmanyrespectssimilartothoseofingingivitisatteethandincludeclassicalsymptomsofinflammation,suchasswellingandredness.第25题单选题(4分)()isagooddiscriminatingindicatorofperi-implantmucositis.ABleedingonprobingBrednessCbonelossDboneregeneration课后作业第1题判断题(6分)Generally,theforeignbodyreactionoccursaftertheimplantationofthebiologicallyinertmaterialintothebody,andthefibroustissueisformedonthesurface.第2题判断题(6分)Bioactivematerialsmustbedegradablematerials第3题单选题(6分)WhichofthefollowingisnotthemainfunctionofGTRbarriermembraneforperiodontaltissuerepairandregeneration:()ABarriersofttissueingrowthBProtectthewoundCAnti-bacterialand