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注:不含主观题第1题单选题(20分)Thetherapeuticindexis().AtheratioofED90/LD10BtheratioofED95/LD5CtheratioofLD50/ED50DthedistancebetweenED50andLD50E
theratioofED50/LD50第2题单选题(20分)IfthevalueofpD2isgreater,itmeansthat().Atheaffinitybetweendrugandreceptorisstronger,thedoseofdrugusedintheexperimentislargerBtheaffinitybetweendrugandreceptorisstronger,thedoseofdrugusedintheexperimentissmallerCtheaffinitybetweendrugandreceptorisweaker,thedoseofdrugusedintheexperimentissmaller
Dtheaffinitybetweendrugandreceptorisweaker,thedoseofdrugusedintheexperimentislargerEtheaffinitybetweendrugandreceptorcannotbecompared第3题单选题(20分)Thefeatureofagonistiswith().Alowreceptoraffinity,α=1Blowreceptoraffinity,α=0Chighreceptoraffinity,α<1
Dhighreceptoraffinity,α=0Ehighreceptoraffinity,α=1正确答案:E第4题单选题(20分)Oneofthefollowingreceptorsisaligand-gatedionchannel().AMreceptor
BGABABreceptorCNreceptor
DmGluRs
ED1receptor
第5题单选题(20分)Youneedtograduallyreducetheamountofpropranololafteryoutakeforalongtimetotreathypertensionbeforeswitchingtoothermedications.Thisistoavoid().AsidereactionBtoxicreactionCresidualeffectDwithdrawalreactionEallergicreactionPharmacokenetics第1题单选题(1分)
Ift1/2ofcertaindrugis8hours,accordingtothefirstordereliminationkinetics,thetimerequiredtoreachsteadystateisabout(
)A8hoursB16hoursC24hoursD40hoursE50hours第2题单选题(1分)
InpH=5.0solution,aweakaciddrugdissociatesabout50%,thepKavalueis(
)A4B5C6D7E8第3题单选题(1分)Thecorrecttreatmentandrationalforphenobarbitalsodiumpoisoningisthat(
)Aalkalizingtheurine,thedissociationisreduced,sothatthereabsorptionofphenobarbitalsodiumintherenaltubulesisreducedBalkalizingtheurine,thedissociationisincreased,sothatthereabsorptionofphenobarbitalsodiumintherenaltubulesisreducedCacidifingtheurine,thedissociationisincreased,sothatthereabsorptionofphenobarbitalsodiumintherenaltubulesisreducedDacidifingtheurine,thedissociationisreduced,sothatthereabsorptionofphenobarbitalsodiumintherenaltubulesisincreasedEacidifingtheurine,thedissociationisincreased,sothatthereabsorptionofphenobarbitalsodiumintherenaltubulesisincreased第4题单选题(1分)Probenecidcanincreasetheefficacyofpenicillin,because(
)AprobenecidcanpromotetheabsorptionofpenicillinBtheyhavesynergicbactericidalmechanismsCprobenecidcaninhibitpenicillinaseDprobenecidcanpromotemetabolismofpenicillinEprobenecidcompeteswithpenicillinforexcretionintherenaltubules正确答案:E第5题单选题(1分)Thefollowingdescriptionaboutthefirst-ordereliminationkineticsiscorrect(
)ATherateofeliminationisproportionaltothedrugconcentrationintheplasmaBThet1/2is0.5C0/κCThetimetoreachplateauisusuallyequaltosixhalf-livesDThelargerthedose,thelongerthet1/2ETheAUCisnotproportionaltothesingledosegivenCholinoceptor-Activating&Cholinesterase-Inhibit第1题单选题(20分)Thecholinoceptoractivatingdrugwhichiscommonlyusedfortreatingglaucomais(
)
Aneostigmine
BgalanthamineCpilocarpineDnicotineEphysostigmine第2题单选题(20分)
Neostigmineis(
)
AanMreceptorblockerBanNreceptorblockerCacholinesterasereactivator
DareversibleinhibitorofcholinesteraseEanirreversibleinhibitorofcholinesterase第3题单选题(20分)Theeffectsofpilocarpineontheeyesinclude(
)Amiosis,increasedintraocularpressure,myopiaBmiosis,decreasedintraocularpressure,myopiaCmiosis,decreasedintraocularpressure,cycloplegiaDmydriasis,decreasedintraocularpressure,cycloplegiaEmydriasis,increasedintraocularpressure,cycloplegia第4题多选题(20分)Mreceptorstimulationwillcause(
)AinotropiceffectontheheartBganglionexcitementCskeletalmusclescontractionDbronchialsmoothmusclecontractionE
glandssecretion正确答案:ADE第5题多选题(20分)DrugsthatcanactivateMandNreceptorsare(
)AacetylcholineBpilocarpineCcarbacolDnicotineEneostigmine正确答案:ACEcholinoceptorblockingdrugs第1题单选题(20分)Themusclerelaxantthatcausestransientfasciculusfibrillationafteradministrationis(
).AsuxamethoniumBtubocurarineCmivacuriumDdoxacuriumErocuronium第2题单选题(20分)Thedrugthatcanbeusedtorelieveurinaryurgency,urinaryfrequencyandincontinenceafterprostatectomyis(
).ApilocarpineBacetylcholine
C
atropineDphysostigmineEneostigmine第3题单选题(20分)Thedrugthathasmoreselectiveforvascularspasmolysisis
().AhomatropineBscopolamineCephedrineDanisodamineEphysostigmine第4题单选题(20分)
Thedrugwithsignificantcentralinhibitoryeffectis()ApilocarpineBscopolamineCanisodamineD
atropineEephedrine第5题多选题(20分)Neostigminecanbeusedtodetoxifywhenoverdosing().Asuxamethonium
BtubocurarineCmivacuriumDdoxacuriumErocuronium正确答案:BCDEadrenoceptoractivatingdrugs第1题单选题(20分)Thedrughaseffectwhenoraladministration(
)
A
dobutamineB
dopamineCephedrineDaramineEnorepinephrine第2题单选题(20分)Bonusinjectionofadrenalinewillcause(
)A
amarkedfallindiastolicpressureBariseinbloodpressureandthenafallinbloodpressureCafallinbloodpressureandthenariseinbloodpressureD
nochangeinbloodpressureEonlyamarkedriseinbloodpressure第3题多选题(20分)Thedrugsthathaveweakcentral
excitationactionare(
)
AadrenalineBnoradrenalinC
dopamineDisoprenalineEephedrine正确答案:ABCD第4题单选题(20分)Thefollowingdrugthatusuallycombineswithsomelocalanestheticsis(
).AadrenalineBnoradrenalinCdopamineDisoprenalineEephedrine第5题多选题(20分)Thedrugsusingincardiacarrestare()AnoradrenalinB
adrenalineCdopamine
D
isoprenalineEatropine正确答案:BDadenoceptorantagonists第1题单选题(20分)Prazosincanselectivelyblock(
).AD1receptorsB
α1adrenoceptorsC
α2adrenoceptorsDβ1adrenoceptorsEβ2adrenoceptors第2题单选题(20分)Thedrugthatcanreversethepressorresponseofepinephrineis(
).AαreceptorantagonistBβreceptorantagonistCMreceptorblockerDNreceptorblockerEDopaminereceptorblocker第3题单选题(20分)Whennorepinephrineinfiltratedintosubcutaneoustissueduringintravenousdrip,thedrugofchoiceis(
).AisoproterenolBatropineCdopamineDpropranololEphentolamine正确答案:E第4题多选题(20分)Thecontraindicationofβ-blockersincludes(
).AsupraventriculararrhythmiaBhypertensionCasthma
D
sinusbradycardiaEhyperthyroidism正确答案:CD第5题多选题(20分)Thefollowingdrugsthatcanbeusedtotreatglaucomaare
().ApropranololBtimololCpilocarpineDcarvedilolEphysostigmine正确答案:BCEDrugsthatactinthecentralnervoussystem第1题多选题(2分)ThecellsinthebrainincludeAneuronBoligodendrocyteCmicrogliaDastrocyte正确答案:ABCD第2题多选题(2分)TheionotropicreceptordoesnotincludeANMDAreceptorBGABABreceptorCnicotinicreceptorD5-HT2receptor正确答案:BD第3题判断题(1分)D2-likereceptorincludeD2,D3,D4subtype.第4题判断题(1分)Inthenervoussystem,peptidesdonotco-existwithtypicaltransmitterinthesameneuron.第5题单选题(1分)Excitotoxicityisrelatedtotheactivationof
AAMPAreceptorBNMDAreceptorCKAreceptorDmGluRreceptorSedative-hypnoticdrugs第1题判断题(1分)DiazepamincreasesthedurationofREMsleep第2题判断题(1分)Diazepamcanbeusedasintravenousanesthetic.第3题单选题(1分)Theabstinencesyndromofdiazepamcanbeinducedby
AphenobarbitalBflumazenilCnaloxoneDatropine第4题判断题(1分)DrugAisusedtogetherwithphenobarbital,therefore,thedosesofdrugAshouldbeincreased.第5题多选题(2分)TheeffectsofdiazepamonthesleeppatternincludeAdecreasethesleeplatency
BdecreasetheREMsleepCincreasetheNREMstage2sleepDincreasetheNREMstage3sleep正确答案:ACAntiseizuredrugs第1题判断题(1分)Oraladministrationofdiazepamistheprimataryagentforstatusepileptics.第2题多选题(2分)Toreliefthetoxicityofphenytoin,thecombineddrugisAVitaminDBVitaminACCalciumtabeletDFolate正确答案:ACD第3题单选题(1分)Ethoxumideistheprimaryagentfortreatmentof
AAbsenceseizureBTonic-clonicseizureCSimplepartialseizureDMyoclonicseizure第4题多选题(2分)Thedrugthatcanbeusedtotreattrigeminalneuralgiasis
ANitrazepamBPhenytoinCValproicacidDCarbamazepine正确答案:BD第5题判断题(1分)Valproicacidiseffectiveinallkindsofseizuretypes.
Antiparkinsonismdrugs第1题判断题(1分)DopaminecanusedinthetreatmentofParkinsondisease第2题多选题(2分)Therecommendedcombinationwithlevodopais
AVitaminB6BCarbidopaCSelegilineDReserpine正确答案:BC第3题单选题(1分)Thedopaminereceptoragonistis
AlevodopaBcarbidopaCbromocriptineDamantadine第4题判断题(1分)Levodopaisagoodchoicefortreatmentofdrug-inducedparkinsonism.第5题多选题(2分)TheanticholinergicsusedtotreatPDis
AatropineBbenzhexolCselegilineDtolcapone正确答案:BDrugsforpsychiatricdisorders第1题单选题(1分)Chlorpromazineiseffectiveinvomiting,exceptthevomitinginducedbyAdrugintoxicationBvestibulardisorderCGIdiscomfortDpregnancy第2题多选题(2分)Thedopaminergicpathwaythatrelatedtotheantipsychoticeffectofchlorpromazineis
ANigrostriataltractBMesolimbictractCMesocorticaltractDTuberoinfundibulartract正确答案:BC第3题多选题(2分)Thedrugsusedtotreatmaniainclude
Alithium
BcarbamazepineCvalproicacidDolanzepine正确答案:ABCD第4题判断题(1分)ClozepinehashighselectivityforD2receptor.
第5题多选题(2分)ThefollowingsymptomsthatcanbeimprovedbybenzhexolareAAkathisiaBAcutemusculardystoniasCTardivedyskinesia
DParkinsonism正确答案:ABDOpioidanalgesics第1题单选题(1分)MorphineisnotsensitivetoAneuropathicpainBdullpain
Csharppain
Dinflammatorypain
第2题多选题(2分)Type2psychotropicdrugsdonotincludeApentazocineBmorphineCmethadoneDfentanyl正确答案:BCD第3题多选题(2分)ThedrugthateffectiveinmorphineintoxicationisApethedineBmethadoneCcodeineDnaloxone正确答案:BD第4题多选题(2分)Thepotencyofmorphineislessthanthatof
AmeperidineBsufentanilCcodeineDmethadone正确答案:B第5题判断题(1分)Pethidinedelaysthebirthprocess.NSAIDs第1题单选题(1分)TheselectiveCOX-2inhibitorisAAspirinBDiclofenacCCelecoxibDIndomethacin第2题判断题(1分)Aspirin(0.5g)fortheprophylaxisofthromboembolicdisease第3题单选题(1分)ThedrugforpaediatricuseasantipyreticisAAspirin
BCelecoxibCAcetaminophenDIndomethacin
第4题单选题(1分)Inthefollwingdrugs,whichonehasthemostpotentCOXinhibition?AAspirinBIndomethacinCMeloxicamDDiclofenac第5题多选题(2分)ThecontraindicationofaspirinincludeAasthmaBneonateChepaticdysfunctionDvitaminKdeficiency正确答案:ABCDDiuretics第1题单选题(20分)()isapotassium-sparingdiureticagent.AfurosemideBhydrochlorathiazideCacetazolamideDspironolactone第2题单选题(20分)Furosemideregulatereabsorptionat().AtheloopofHenleBproximaltubuleCdistalconcolutedtubuleDcollectingduct第3题单选题(20分)()couldinhibitsodiumpotassiumtransporter.AfurosemideBhydrochlorathiazide
CacetazolamideDspironolactone第4题判断题(20分)hydrochlorathiazideishigh-efficacydiureticagent.第5题判断题(20分)furosemideinhibitbothdilutingandconcentrationoftherenaltubulsystem.Cardiacglycosides第1题单选题(20分)()couldnotbeusedforthetreatmentofcongestiveheartfailure.ARAASinhibitorsBDiureticsCβ-blockersDCardiacglycosidesEAminoglycosides正确答案:E第2题单选题(20分)Cardiacglycosideswillnot
()AincreaseoxygenconsumptionBshowpositiveinotropiceffectCshownegativechronotropiceffectDshownegativedromotropiceffect
Ecausefishhook-likeSTsegment第3题多选题(20分)Cardiacglycosidescouldbeusedforthetreatmentof()AatrialfibrillationBatrialflutterCcogestiveheartfailureDA-VnodeblockadeEhypertension正确答案:ABC第4题判断题(20分)TheuseofcardiacglycosidesistheonlyreasontoinduceTwavedepressionorinversion,whichisalsoknownasfishhook-likeSTsegment.第5题判断题(20分)β-Blockersshouldnotbeusedforallthepatientswithcongestiveheartfailure.antihypertensiveagents第1题多选题(20分)Thefirstantihypertensivedrugsinclude().AACEinhibitorsBβ-AdrenoceptorblockingagentsCCalciumchannelantagonistsDDiuretics正确答案:ABCD第2题判断题(20分)Inlongtermtherapy,thereasonwhydiureticscoulddecreasebloodpressureisthereductioninperipheralvascularresistance.第3题判断题(20分)Whencalciumantagonistsareusedagainsthypertension,theywillinduce
orthostatichypotension.第4题单选题(20分)()willproduce
withdrawalsyndromeinpatientwithhypertension.AAT1receptorblockersBβ-blockersCcalciumchannelantagonistsDdiuretics第5题单选题(20分)()couldcauseslightsympatheticreflex.
htreflexsympatheticactivation
ALorsartanBCaptoprilCNifedipineDPropranololRAASinhibitors第1题单选题(30分)ThefollowingstatementaboutRAASinhibitorsiscorrectexceptthat(
)AaliskirenisarenininhibitorBspironolactonemayinducehyperkalemiaCeplerenoneisaselectivealdosteroneantagonistDcaptoprilmayinducedrycoughElosartancanbeindicatedinthepatientswithrenalarterystenosis正确答案:E第2题单选题(30分)Themechamismofactionofenalaprilis(
)AdirectlyblockingAT1receptorsBinhibitingtheactivityofACECdirectlyblockingAT2receptorsDblockingaldosteronereceptorsEactivatingNOsynthase第3题Anti-anginalagetns第1题单选题(20分)Fortreatingvariantangina,thepreferredagentisApropranololBnifedipineCdiltiazemDcarvedilolEprazosin第2题单选题(20分)Themechanismofactionofnitroglycerinisrelatedto
ApotassiumchannelblockadeBbeta-receptor
blockade
CsodiumchannelblockadeDcalciumchannelblockadeENOrelease正确答案:E第3题多选题(30分)Theactionsofcalciumchannelblockersinclude
AhavingapronouncedeffectonmostvenousbedsBrelaxingarterialsmoothmuscleChaving
negativeinotropiceffect
Dhavingpositive
dromotropiceffect
Ehavingnegative
chronotropiceffect
正确答案:BCE第4题多选题(30分)Thefollowingstatementaboutantianginaleffectsofnitroglycinand/orpropranololarecorrectincludingthatAnitroglycerincanattenuatepropranolol-inducedincreasedLVDEPBpropranololcanattenuatenitroglycerin-inducedreflextachycardiaandincreaseincardiaccontractilityCContinuousexposuretohighdosesofnitroglycerininducetoleranceDpropranololissuitablefortreatingvariantanginaEheadacheisthecommonadverseeffectinducedby
nitroglycerin正确答案:ABCEAntihyperlipidemicagents第1题单选题(30分)Thefollowingstatementsaboutantihyperlipidemicdrugsarecorrectexceptthat()AHMG-CoAreductaseinhibitors
primarilyreduces
LDLandTCBniacinprimarilyreducesLDLandTCCfibratesprimarilyreduceVLDLandTGDbileacid-bindingresins
primarilyreduceLDLandTCEEzetimibemayincreaseHDLlevel第2题单选题(30分)Statinslowerbloodcholesterollevelprimarilyby(
)AinhibitingcholesterolabsorptionfromtheintestineBinhibitingchloesterolacyltransferaseCinhibitingHMG-CoAreductaseDactivatingPPARαEbindingbileacid第3题多选题(40分)Thefollowingstatementsaboutstatinsarecorrectincludingthatthey()AprimarilyreduceLDLandTClevelsBsignificantlylowerTGlevelCmayinducerhabdomyolysisDareeffectiveforpatientswithhomozygousfamilialhypercholesterolemia
Earecontraindicatedinpregnantwomen
正确答案:ACEantiarrhythmicdrugs第1题单选题(30分)ThefollowingstatementaboutantiarrhythmicdrugsiscorrectexceptthatApropranololcanbeusedfortreating
ventriculararrhythmiasinpatientswithmyocardialinfarction
Bamiodaronecanbeusedfortreatingbothsupraventricularandventriculararrhythmias
Cverapamilisprimarilyusedinthetreatmentofparoxysmalsupraventriculararrhythmias
Dlidocaineis
mainlyusedinthetreatmentofventriculararrhythmiasEquinidineinonlyusedfortreating
ventriculararrhythmias正确答案:E第2题单选题(30分)Theprimarytreatmentfordigitalis-inducedventriculartachycardiaisApropafenone
Bpropranolol
CverapamilDphenytoinsodium
Ediltiazem
第3题多选题(40分)ThefollowingstatementsaboutadverseeffectsofantiarrhythmicdrugsarecorrectincludingthatAqunidineinducescinchonismBthecommonadverseeffectoflidocineisneurologicreaction.CamiodaroneshortensQTintervalDverapamilmayinduceAVblock
Epropranololmayinducesinusbradycardia正确答案:ABDEAdrenocorticosteroids第1题单选题(20分)Theprimaryagentforanaphylacticshockis().AephedrineBisoprenalineCnoradrenalineDglucocorticoidsEadrenaline正确答案:E第2题单选题(20分)Thepharmacologicaleffectsofglucocorticoidsincludethefollowings
except()Aanti-inflammatoryeffectsBacceleratingthegrowthinchildrenCanti-shockactionDanti-toxicactionEimmunosuppressiveeffects第3题判断题(20分)Glucocorticoidscouldneutralizeendotoxins.第4题判断题(20分)Suddenacutewithdrawalof
glucocorticoidsafterlong-termusewillcausereboundreaction.第5题判断题(20分)DelayedhealingofthewoundafterGCisinducedbyitseffectonthemetabolismofprotein.
Thyroid&antithyroiddrugs&pancretichormones&antidiabeticdrugs第1题单选题(20分)()couldbeusedforsimplegoiter.AtriiodothyronineBβblockerClargedoseiodideDradioiodineEthioureas第2题单选题(20分)()isanoralantidiabeticagentbystimulatingthesecretionof
insulin.AtolbutamideBmiglitolCmetforminDrosiglitazoneEacarbose第3题判断题(20分)Rosiglitazonecouldincreaseinsulin
sensitivityinpatientswithdiabetes.
第4题判断题(20分)Lowdoseiodidecouldbeusedforthetreatmentorpreventionofsimplegoiter.第5题判断题(20分)Largedoseofiodidecouldnotdecreasethesizeandvasculatureofdiffusegoiter.Drugsusedinasthma第1题单选题(25分)()couldbeusedtocontrolasthmaattack.Aβ-adrenoceptorstimulantsBLeukotrienepathwayinhibitorsCinhibitorofmastcelldegranulationDGlucocorticoids第2题单选题(25分)()istheβ2-selectiveadrenoceptor
agonistforthetreatmentofasthma.AterbutalineBtheophyllineCipratropineDbeclomethasone第3题判断题(25分)β2
receptor
antagonistsuchaspropranololcouldbeusedtoforhypertensivepatientwithconcomitantasthma.第4题判断题(25分)Thefirstchoiceantihypertensiveagentcouldnotbeusedtocontrolbloodpressureforpatientwithconcomitantasthma.Drugsforpepticulcer第1题单选题(20分)Lansoprazolebelongsto().AantacidsBH2receptorantagonistsCprotonpumpinhibitorsDmucosalprotectiveagents第2题单选题(20分)ThefollowingdrugthatcanblockH2receptoris(
).AcimetidineBpirenzepineCproglumideDomeprazole第3题单选题(20分)Thefollowingdrugthatformsaprotectivefilminacidicenvironmentis(
).AmisoprostolBsucralfateCaluminiumhydroxideDfamotidine第4题多选题(20分)Theanti-ulceragentsthathavesuppressiveeffectonH.pyloriinclude(
).AcimetidineBsucralfateCmagnesiumhydroxideDomeprazole正确答案:BD第5题判断题(20分)Mreceptorblockerthatisusedintreatmentofpepticulcerisatropine.Drugsactingonbloodandbloodformingorgans第1题单选题(20分)Totreatmacrocyticanemiawithneuropathy,weshoulduse().AironBfolicacid
CvitaminB12DEPO第2题单选题(20分)Topreventthehemorrhageofnewborns,weusuallyuse(
).APAMBABVitK1
CprotamineDepinephrine第3题多选题(20分)Thefollowingdrugshaveanticoagulatedeffectinvivoandinvitro(
).Aenoxaparin
B
lepirudinCwarfarinDvitaminK正确答案:AB第4题多选题(20分)Theantiplateletdrugsare().AaspirinBdipyridamoleCabciximab
Dclopidogrel正确答案:ABCD第5题判断题(20分)WarfarininhibitstheactivityofclottingfactorsIX,X,II,VII.exerciseforlecture1and2第1题单选题(20分)Thefollowingdrugthatbelongtopenicillinase-resistantpenicillinsis
(
)A
Ampicillin
BCarbenicillinC
NafcillinDAmoxicillinE
Piperacillin第2题单选题(20分)Thefirstchoicefortherescueofpenicillin-induced
anaphylacticshockis(
)
AadrenalinBdiphenhydramineC
prednisoneDatropineE
isoprenaline第3题单选题(20分)Whenpenicillinisusedtotreatthefollowingdiseases,ThatispossibletocauseHerxheimerreactionis(
)A
epidemiccerebrospinalmeningitisBlobarpneumoniaCstreptococcusviridansendocarditisDsyphilisE
gasgangrene第4题单选题(20分)Inthefollowingdescriptionforchemotherapeuticindex,theincorrectoneis(
)
AThechemotherapyindexcanbeexpressedas:LD50/ED50B
TheChemotherapeuticindexindicatesthesafetyofchemotherapeuticdrugsC
Thechemotherapyindexcanbeexpressedas:LD5/ED95D
Thechemotherapyindexishigher,thetreatmenteffectisthebetterEIfthechemotherapeuticindexishigher,thedrugisrelativelysafer.第5题单选题(20分)Amongthefollowingcharacteristicsofampicillin,theincorrectoneis()A
AmpicillinandpenicillinGhavecross-allergicreaction。BAmpicillinisstableinacidandrelativelywellabsorbedafteroraladministrationCAmpicillinisactiveagainstSalmonellaDAmpicilliniseffectiveagainstgram-negativebacteriaEAmpicillinisactiveagainstpenicillin-resistantStaphylococcusaureus.正确答案:Eexerciseforlecture3andlecture4第1题单选题(20分)Thefollowingdrugthatcansuppressesproteinsynthesisbybindingtothe30ssubunitisA
erythromycinBcefazolinC
clindamycinDvancomycinEgentamicin正确答案:E第2题单选题(20分)Streptomycinisthefirstchoiceinthetreatmentforthefollowinginfectiousdisease
()AacutepneumoniaBtonsillitisCbacterialendocarditisDbubonicplagueEmeningitis第3题单选题(20分)Amongthefollowingdescriptionofvancomycin,theincorrectoneis()AVancomycincanbeadministeredorallytotreatpseudomembranouscolitisBVancomycinisactiveagainstmethicillin-resistantStaphylococcusaureusCThereiscross-resistancebetweencephalosporinsandvancomycinDRapidintravenousinfusionmaycauseextremeflushingEVancomycincancausecellwalldefectinsensitivebacteria第4题单选题(20分)Thefollowingcharacteristicdonotbelongtocommoncharacteristicsofaminoglycosideantibioticsis()AAminoglycosideantibioticshavecertainnephrotoxicityandototoxicity.B
AminoglycosideantibioticshavestrongpolarityandaredifficulttobeabsorbedbyoraladministrationCAminoglycosideantibioticscanbindtobacterial30sribosomalsubunitandinhibitproteinsynthesis.DAminoglycosideantibioticshavehighantibacterialactivityagainstGram-negativebacteria.EAminoglycosideantibioticshavehighantibacterialactivityagainstGram-positivebacteria.正确答案:E第5题单选题(20分)Theantibacterialmechanismofcycloserineis()AInhibitionofbacterialcellwallsynthesisBTochangethepermeabilityofbacterialmembraneCInhibitionofproteinsynthesisDInhibitionofdihydrofolatereductaseEInhibitionofbacterialDNAgyraseexerciseforlecture5andlecture6第1题单选题(20分)
Thefollowingdrugthatcansuppressesproteinsynthesisbybindingtothe50ssubunitis
(
)AerythromycinBcefazolinCtetracyclineDvancomycinEgentamicin第2题单选题(20分)Thatinthefollowingdrugsmostfrequentlycausepseudomembranouscolitisis()AvancomycinBmetronidazoleC
penicillinDgentamicinE
clindamycin正确答案:E第3题单选题(20分)
ThepreferreddrugforRickettsiainfectionis()AtetracyclineBsulfamethoxazoleCgentamicin
DstreptomycinEpolymyxin第4题单选题(20分)Inthefollowingdescriptionforchloramphenicol,theincorrectoneis
()AChloramphenicolbindstothe30ssubunitofthebacterialribosome,blockingtheaminoacidtRNAtotheacceptorsite.BChloramphenicolisonlyusedinthetreatmentoflife-threateningdis
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