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Morganstanley
April10,202604:01AMGMT
GlobalThematicResearch:RevisitingOur10Predictions
April7,2026
StephenByrd–GlobalHeadofThematicandSustainabilityResearch|EquityStrategistMichelleWeaver–HeadofUSThematicResearch|EquityStrategist
MORGANSTANLEY&CO.LLC
MorganStanleydoesandseekstodobusinesswithcompaniescoveredinMorganStanleyResearch.Asaresult,investorsshouldbeawarethatthefirmmayhaveaconflictofinterestthatcouldaffecttheobjectivityofMorganStanleyResearch.InvestorsshouldconsiderMorganStanleyResearchasonlyasinglefactorinmakingtheirinvestmentdecision.
Foranalystcertificationandotherimportantdisclosures,refertotheDisclosureSection,locatedattheendofthisreport.
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WhatWeWillCoverinThisPresentation
ExecutiveSummary
RevisitingOur10ThematicPredictionsfor2026
WaystoPlayOurThematicPredictions
KeyAnalyticalToolsHelpfultoThematicInvesting
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Source:MorganStanleyResearch
ExecutiveSummary
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RevisitingOur10ThematicPredictionsALotCanHappenin3Months
•Catalysts:Irandynamics,LLMreleases,globalenergypolicy,AIinfrastructuregrowth,computedemandgrowth,AIand MultipolarWorldintersections.
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Source:MorganStanleyResearch
Sincepublishingour10ThematicpredictionsinJanuary,wehaveseenmanydevelopmentsthathavedriventhesepredictionstobecomekeymarketdrivers
•4predictionsarecloselyintertwined,andarelikelytocontinuetodrivealphaandinvestordebatein2026andbeyond:non-linearLLMimprovement,rapidgrowthincomputedemand,AItechtransfer,andAIdisruption/deflation/labor
impacts
•OurThematiccategorieshaveperformedwell:In2025/YTD2026,ourcategorieswereup38%/7%onaverage,outperformingtheS&P500by27%/12%
•Thebiggeststoryistheshortageofcompute,whichwillinourviewbeexacerbatedbyupcomingUSLLMreleases
showingastepchangeincreaseincapabilities–wearefocusedonthe“computebottlenecks”whichincludelabor,gridaccess,memory,backupgenerationandotherkeydatacentercomponentssuchasconduit
•OtherThematiccategorieswefavor:Defense,Healthcare,AIAdopterswithpricingpower,Humanoids
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OverviewofOurCategoriesofStocksWithinEachTheme
AI&TechDiffusion
•Webelieve2025willbetheyearoftheAIAdopter:
companiesthatcan
leverageAItoimproveresults
•Ourin-depthanalysisofAIusecasesshowshighROIforthecapexspentbyAIEnablerstodrivethe
Adoptionusecases
•ThishighROIonAIcapexinturndrives2categoriesofstocks:AIInfrastructure
(alloftheequipmentacrosstheAIvaluechainrequiredtodevelopanddeployAI
capabilities)andthe
Humanoid100(enhancingroboticswithAIcapabilities)
FutureofEnergy
•PoweringAIisakey
subsetofAIInfrastructure,andisakeybottlenecktoAIdeployment
•MultipleDecarbonization
categories(Nuclear
Renaissance,Europe’s
LowDecarbDiet,Clean
Energy&StoragePlayers,CarbonasaCommodity)aredrivenbypower
demandgrowth,technologyimprovementsand
customer+governmentfocusonreducingcarbonemissions
•Multiplecategories
(GlobalizationofNaturalGas,EnergySecurity)
haveadirectlinkagetoourMultipolarWorldTheme
SocietalShifts
•FutureofFood&
BeveragesandDiabesityEcosystemaredrivenbyinnovationthatimpacts
whatweconsumedaily
•JapanLongevity
representsa“postcardfromthefuture”intermsof
impactsfromanagingpopulation
•Leveragingtechnologyforbetterhealthoutcomes
drivesAI+HealthCareandSmartChemo
•PreparingforanAging
Populationisdrivenbytheevolvingfinancialneedsinan“AgeofAgeing”
•AI-DrivenJob
DisplacementandRe-
Skillingaddressesarangeofemploymentimpacts
MultipolarWorld
•TheRiseinDefense
Spendingisevident
globallyasgovernments
adjusttoamoreuncertain
securityenvironment;we
seesignificanttechnologicalinnovationinDefense
•China’sdominanceinkeymetals&mineralsisa
potentialsupplychain
vulnerability;ourCritical
Mineralscategoryincludescompaniespositionedto
benefitfromsupplychaindiversification
•OurTechLocalizationcategoryincludesstocksthatwouldbenefitfromlimitedavailabilityof
WesternAIequipmentinChina
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Source:MorganStanleyResearch
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PerformanceofOurThematicCategoriesYTDin2026
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•Thematicinvestingisapowerfuldriverof
alpha.In2025,our
Thematicstock
categoriesonaveragewereup38%,
outperformingMSCIWorldandtheS&P
500by16%and27%,respectively
•YTD2026,our
Thematicstock
categoriesareup7%onaverage,
significantly
outperformingS&P
500andMSCIWorld
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KeyRecentEventsImpactingOur10ThematicPredictions
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Source:MorganStanleyResearch
1."Twoworlds"ofLLMprogressandAIadoption:METRanalysisshowingsurprisinglystrongnon-linearityoftaskduration;reportsofupcomingUSLLMswithstepchangeincreasesincapabilities;frontierLLMsactingaspartnersinsolvingopenproblemsinphysics;NYTimesdatashowing54%preferenceforAI-generatedarticles
2.Computedemandexceedssupply:~250%increaseinweeklytokenusagefromJanuary2026toMarch2026;theOpenClawphenomenon;signsofLLMusershittingtokenlimits
3.ArobustUSpolicyagenda:Iranconflictunderscoresourmilitarytechprediction;upcomingUSelectionwillfeaturepowerandenergypriceaffordability(driventhemovetooff-griddatacenters);riskofUAEdatacenterattack
underscoresimportanceofsecurityofcriticalcomputeresources
4.AItechtransfer,coupledwithpushfornationalself-sufficiencyandgreater"grossdomesticintelligence":Ifprediction#1materializesinApril-June,webelievethispredictionwilllikelyfollow
5.Thepoliticsofenergy:Manydatapointssuggestingabacklashagainstdatacentergrowthinmanypartsoftheworld(Hawley-Blumenthalbillisnotable);wemayseesignificantgovernmentsupportgloballyforenergysecurity
6.GreaterconvergenceofAI+energy:MetafundingofTerrapower;MetafundingofLouisianapowerinfrastructure;
wehavenotyetseenawaveofmajorstepsbyAIplayerstogaingreatercontrolofenergyinfrastructure
7.Chinagrowstechnologymanufacturingmarketshare,whiletheUSexperiencesa“Re-shoringRenaissance“:
upcomingUS-Chinasummit;Section232USgovernmentactiononchipexports;rapidroboticsadvancesledbyChina
8.InLatinAmerica,atrifectaofchange:LatinAmericaincreasinglyappeals,givenits“physicalabundance”
9.Re-skillinginitiatives+AIjoblosspolicyintervention:Thishasjustbegun;politicalawarenessgrowsrapidly
10."TransformativeAI"drivesdeflation,highercapex,changesinassetvaluations,andnationalcompetitiveness:significantinvestorinterestintherisingvalueforassetsthatcannotbe"replicated"byAI
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Source:MorganStanleyResearch
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TheIntersectionsBetweenOurThemes:UnderExploredAlphaPotential
MultipolarWorld
AI&TechDiffusionFutureofEnergy
SocietalShifts
(1)Strategicnational
importanceofAIleadership
(2)AItechnologytransferrestrictions:howeffective?
(3)Can"nationalAI
champions"develop
competitiveAIadvantages
withinoneormoreverticals?
(4)Strategicassets:energy,compute,robotics,drones,frontiermodeldevelopment
(5)AIandtheFutureofWarfare
(1)AI-drivenemploymentimpacts:impactonratioofworkerstoretirees
(2)Challengingdemographicsacrossmanygeographies
(3)Potentialforincreasing
disparitiesamongnationswithrespecttoAILifeSciences
technology
(4)Policyresponses:medicalinsurancesubsidies,minimumbasicold-agebenefits
(1)Nationalenergysecurityasastrategicpriority
(2)Industrialcompetitiveness:low,stableenergycosts
(3)Supplychainchallengesconstrainingenergy
infrastructuregrowth
(4)CriticalmaterialsandChina’sdominantposition
(5)EnergyasastrategicassettofuelthegrowthofAI
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TheYearof“ThematicBottlenecks”
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Source:MorganStanleyResearch
Alphagenerationpotentialfromaddressingarangeofbottlenecksin2026relatingtoourKeyThemes
FutureofEnergybottlenecks
•BasedonourPoweringAIdeepdive,weprojectUSdatacenterdeveloperswillfacea10-20%powershortfall
•ThepowerbottleneckfacingAI:Off-gridsolutionssuchasBEandSEI;Bitcoin-to-DCconversionopportunities
•Otherbottlenecksimpactingenergy/powergrowth:shortagesinlabor,transformers,backuppowergeneration
MultipolarWorldbottlenecks
•Shortageofdomesticrareearths,criticalminerals,metalsanduranium–ourCriticalMineralsThematicstockcategorywasthetopperformerin2025(up>100%)
•Lackofdroneandroboticsmanufacturingcapability,withespeciallyacutechallengeswithrespecttodomesticsupplyofkeycomponentssuchasmotorsandactuators–webelievethiswilldrivesignificantUSgovernmentpolicyaction
AI/TechDiffusionbottlenecks
•Ouranalysisshowsasystematicshortageincomputerelativetodemand–beneficiariesincludenotjustchipmanufacturers,butmemoryandopticalnetworkingaswell
SocietalShiftsbottlenecks
•Thebottleneckshereareconceptuallydifferent–therightskillsinaworldofpowerfulAI,labormobility,demographicpressures(agingpopulations),andtheabilityofinstitutions(governments,educationsystems,employers)toadaptfastenoughtoAI-drivendisruption,whichultimatelylimitshowquicklyproductivitygainsandsocialbenefitsfromAIcandiffusethroughtheeconomy
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AI-DrivenDisruption:AssessingtheKeyArguments
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ArgumentsinFavorofDisruption
1.Non-linearrateofLLMimprovementimpliesmuchgreaterabilitytoperformeconomicactivityatextremelylowcost
2.LLMsaredisruptivetoexistinglargebusinessesbecausetheygivesmallteamstheabilitytodevelopnovel,capableservices/productsatafractionofthecostandtime
3.AIdramaticallydropsthecosttoperformawiderangeofknowledgework(andinthelongerterm,throughEmbodiedAI,awiderangeofphysicalwork)
4.TherapidimprovementinAIchipsresultsinarapiddropinthecostofAItoperformawiderangeoftasks
5.AsLLMsbecomemorepowerful,theyarealsobecoming
morecreative(ascanbeseeninarecentOpenAIpaperco-authoredwithseveralleadingPhysicsprofessors)
6.AdvancesinAgenticAIcouldresultineconomicactivityoccurringoutsideoftraditionalcommercialchannels
CounterargumentsAgainsttheAIDisruptionThesis
1.AIAdoptersareshowingrealbenefitstothebottomline
2.EstablishedcompaniesoftenhavesuperiorresourcesthatallowthemtobetterleverageAIcapabilities,includingsubjectmatterexpertiseandproprietarydata
3.Establishedcompanieshavestrongcustomerrelationshipsandadeepunderstandingofcustomerneeds
4.Incumbentsoftenhavesignificantbrandadvantagesand
extensivedistributions/salesnetworksthatarehardtoreplicate
5.Therearesignificant,non-obviousbarrierstoentrysuchas
complianceandgovernancerequirements,anda“trustbarrier”
6.AIwillinmanycases"augment"ratherthan"automate"employees
7.Manyproductsandservicesrequire100%accuracy,
explainabilityandabilitytoauditresults,whichmaypresentaseriouschallengeforLLMs
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AssessingAI“DisruptionMoats”
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Wefoundaquotefromashortessay,fromMichaelBlochatQuietCapital,tobehelpful(emphasisadded):
"InaworldwhereAIcanbuildanysoftware,replicateanyproduct,andautomateanyprocess,whatactuallymakesabusiness
defensible?MostoftheanswersIheararewrong.They'reallbetsonthesamething:thatintelligencedoesn'tget100xfaster,
better,andcheaper.Itwill.Soon.Defensibilityhasalwayscomefromtwothings.Thingsthatarehardtodoandthingsthatarehardtoget.AIismakingthefirstoneworthless.AIcompressesthetimeittakestodothings.Itdoesnotcompressthe
timeittakesforthingstohappen.ThatdistinctionisnowthesinglemostimportantfilterIapplywheninvesting.Fivethingspassit:
1.Compoundingproprietarydata.Notalldataqualifies.Astaticdatasetthatwasmerelyexpensivetocollectwilleventuallybesynthesizedorworkedaround.That'shardtodo,nothardtoget.Themoatislivingdata:proprietaryinformation
continuouslygeneratedthroughoperationsthatarethemselvesdefensible.
2.Networkeffects.Everyuserthatjoinsmakestheproductmorevaluableforeveryotheruser.Thecoldstartproblemmight
actuallygetharderasAImakesittrivialtobuildcompetitors,becausenowahundredwell-builtalternativesarefightingtobootstrapthesamenetwork.Whoeveralreadyhastheliquiditycompounds.
3.Regulatorypermission.Governmentsmoveatthespeedofpolitics,nottechnology...Abankchartertakesyears.FDAapprovaltakesyears.Andthesurfaceareaofregulationisexpanding,notshrinking,becauseasAIcapabilityincreasesthestakesgethigher.Willthespecificformschange?Almostcertainly.Willtheneedforhumanpermissiongoaway?Ican'tseehow.
4.Capitalatscale.Theonealmosteveryoneisunderweighting.TheendgameisphysicalWhenthebottleneckshiftsfrom
softwaretoatoms,theabilitytofinanceanddeploycapitalatmassivescalebecomesoneofthedefiningadvantagesoftheera.Andcapitalaccessisn'tjustmoney.It'sinstitutionaltrust,trackrecord,andrelationshipsthattakedecadestobuild.
5.Physicalinfrastructure.Factories,powerplants,batterynetworks,datacenters...Physicssetsafloorontimelinesthat
intelligencecan'tbreakthrough.Whoeverstartedbuildingfirsthasaleadthatgrowseverymonthacompetitorhasn'tbrokenground.”
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Source:MorganStanleyResearch
RevisitingOur10ThematicPredictions
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Prediction#1:“TwoWorlds”ofLLMProgressandAIAdoption
•WepredictthatAmericanfrontierLLMsachieveastep-changeincreaseincapabilitiesin1H26thatisnotmatched
withinthesametimeframebyChinesecompetitors;ChineseLLMdeveloperscontinuetoreducethecostofpracticalAIapplicationsthatsuitawiderangeofcustomerusecases
•Recentdatapoints:(A)theMETRanalysisshowingthatthebestLLMscanindependentlyperformtasksaslongas>15hours(thescalinglawswouldsuggestweshouldbeat~8hourscurrently),(B)theArtificialAnalysismetricsthatcontinuetoshowrapidprogressioninAIcapabilities,(C)astatementfromSamAltmanduringtherecentIndiaAI
ImpactSummit:"theworldisnotprepared.Wearegoingtohaveextremelycapablemodelssoon"(D)newsofanentrepreneurthatusedDNAsequencingandtheDeepMindAItoolAlphaFoldtodevelopacancervaccineforhisdog,(E)KevinRoose,theTechEditorattheNYTimes,postedthat54%ofreaderspreferredtheAIwritingover
humanwriting,(F)researchshowingthatfrontierLLMscansolveopenproblemsinphysics,and(G)reportsofanunreleasedLLMthatreportedlyrepresentsa"step-change"incapabilitiesinsoftwarecoding,academicreasoning,andcybersecurity.
•Investmentimplications:(A)ThemarketdebatesregardingAIdisruption/deflationwillspreadtomoresectors,buttherewillalsolikelybeamorenuancedassessmentofwhichbusinessmodelsfacemore/lessAIrisk.(B)Demandforcomputewillcontinuetogrowatarapidrate,drivenbyexpansionofAIusecasesandmuchgreatercomputeintensityofAgenticAIandEmbodiedAI
•Thematiccategoriesthatarewellpositioned:AIInfrastructure,PoweringAI,AI+HealthCare
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WeareBullishRegardingtheNon-LinearRateofAICapabilityImprovement
ExcerptsFromLeoAschenbrenner’s“SituationalAwareness”Essay
“AGIby2027isstrikinglyplausible.GPT-2toGPT-4tookusfrom~preschoolerto~smarthigh-schoolerabilitiesin4years…GPT-2toGPT-4
tookusfrom~preschoolerto~smarthigh-
schooler;frombarelybeingabletooutputafewcohesivesentencestoacinghigh-schoolexamsandbeingausefulcodingassistant.Thatwasaninsanejump.Ifthisistheintelligencegapwe’ll
coveroncemore,wherewillthattakeus?We
shouldnotbesurprisedifthattakesusvery,veryfar.Likely,itwilltakeustomodelsthatcan
outperformPhDsandthebestexpertsinafield….WhatImeanisanAIsystemthatcouldfullyautomatemyormyfriends’job,thatcouldfullydotheworkofanAIresearcherorengineer oncemodelscanautomateAIresearch
itself,that’senough—enoughtokickoff
intensefeedbackloops—andwecouldveryquicklymakefurtherprogress,theautomatedAIengineersthemselvessolvingalltheremainingbottleneckstofullyautomatingeverything.”
Source:LeopoldAschenbrenner,Introduction-SITUATIONALAWARENESS:TheDecadeAhead
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RecentRapidIncreasesinLLMTrainingPowerCapacity
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Source:EpochAI,FrontierDataCenters|EpochAI
EpochAIhasanexcellent
trackerofLLMtraining
facilitydevelopment—notetherapidincreases.Keepinmindthat,overtime,an
increaseinpowercapacityyieldsadisproportionatelylargerincreasein
computationalresources,becausetheexaFLOPsperwattincreasesasmore
powerfulchipgenerationsareinstalled
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OpenRouterDataonCodingLLMSplit(OpenvsProprietary)
Source:OpenRouter16
•Softwarecoding,whichisthe
dominanttokenuseramongallLLMusecases,isdominatedbyproprietary
(closed)models
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Prediction#2:ComputeDemandExceedsSupply
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Source:MorganStanleyResearch
•Wepredictdatain2026thatpointstoalikelysignificant,systematicshortageofcomputationalpowerrelativetoextraordinarilyrapidincreasesindemand
•Recentdatapoints:InadditiontotherecentOpenRouterdatashowingasignificantaccelerationintokenusage,wewouldflag(A)thedramaticincreaseinrateofadoptionofAgenticAItools,most
notablyOpenClaw,(B)a~250%increaseinweeklytokenusagegloballyfromearlyJanuarytolastweek(from6.4trilliontokensto22.7trilliontokens),accordingtoOpenRouter,and(C)signsofusagelimitsbeingimposedbyLLMprovidersinordertomanagetherapidgrowthontokendemand
•Investmentimplications:(A)Thiswouldbebullishforanycompanywiththepotentialtode-
bottleneckthedevelopmentofadditionalcomputevolumes(includingchipmanufacturingsupply
chain,memory,"timetopower,"laborneededfordatacenterconstruction,andkeydatacenter
equipmentsuchastransformers,energystorage,andbackupgeneration),bullishforthe"merchantsofcompute"(predominantlytheneoclouds).(B)TherecouldbeashifttowardEnterpriseAIuse
cases,attheexpenseofsomeConsumerusecases.
•Thematiccategoriesthatarewellpositioned:AIInfrastructure,PoweringAI,PowerGridGrowth
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TheComputeSupply-DemandMismatch
Source:EpochAI18
Whywebelievethe
demandforcomputeis
likelytosignificantlyexceedthesupply:
•Projectedcomputeneedsare~3xtheMSprojectedcomputeCAGRfor
NVIDIA
•Weeklytokenusagegrowthisaccelerating
•AverageAItask
complexityisincreasingatanon-linearrate
•AIadoptionisbroadening
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Prediction#3:RobustUSPolicyAgenda
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Source:MorganStanleyResearch
•Theunderlyingprincipleforthispredictionisthatofgreaternationalself-sufficiency,andthishasmanifestedinwayswedidnotpredict.WhilewepredictedthattheTrumpadministrationwouldtakemorerobustactionthanexpectedto
eliminatedependenceonothernationswithrespecttoarangeofcriticalmaterials,webelieveitisclearthatthisdynamicwill"goglobal"inasignificantway
•RecentDefensesectordevelopments:(1)TheIranconflicthasshowntheimportanceof"asymmetricwarfare,"(2)theIranconflictmayalsodrivemanynationstoincreasetheirDefensespending—seeourEuropeanDefense&
AerospaceanalystRossLaw'srecentnotehere,"(3)theincreasingusageofAIinwarfare;(4)theUS"dronegauntlet"fieldtesting,withresultsreleasedinwhichthetopperformerswere,inthisorder,theShrike10Fiberdrone(producedbySkycutter),Ukraine’sSkyfall,theNerosArcher,Napatree,ModalAI,Auterion,UkrainianDefenseDrones,Griffon
Aerospace,NokturnalAI,HaloAeronautics,AscentAerosystemsandFaragePrecision;(5)theUkrainian
militaryworkingwithmultipleMiddleEasternnationsondronedefenseinitiatives;and(6)questionsfromPresidentTrumponthefutureofNATO
•Investmentimplications:Oneofthebigdriversofalphainglobalmarketsfortheremainderof2026,andlikely2027andbeyond,isamajorpushamongmanynationstoeliminatedependenceonothernationsforthemostimportant
driversofnationaleconomichealthandprosperity,rangingfromenergytonationalsecuritytotechnological
competitiveness.Globally,wecontinuetoexpectanincreaseinmilitaryspending,withalargeincreaseinmilitarytechsuchasdrones/counter-dronedefense,3Dprinting,electronicwarfare,cyber,directedenergyandspace
•Thematiccategoriesthatarewellpositioned:Defense,CriticalMinerals,NuclearRenaissance,CleanEnergy+Storage,Europe'sLowDecarbDiet,EnergySecurity,GlobalizationofNaturalGas.
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CriticalMinerals:SupplyAndGovernmentPolicyReaction
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Source:MorganStanleyResearch,
E
Recentcriticalmineralsdevelopments:
(1)"PaxSilica"fundingcommitments,whichcouldultimatelytotalinthetrillionsofdollars,aswellasseveraladditionalcountriesjoiningthisinitiative
(2)AvarietyofEUinitiativestosecureaccesstocriticalminerals
(3)TheUSgovernment"ProjectVault"initiative,withagoaltostockpileanymineralsthattheUSGSdesignatesas"critical"(thelistofsuchmineralscanbefoundhere)
TotheextentthatAIcapabilitiesincreaserapidlyin2026,especiallyifthisdegreeofincreaseisunevenamong
nations,webelievemanynationswillconsidertheir
envelopesofvulnerabilitytoothernationsshouldtensionsriseduetoheightenedAIcompetition
AUSDepartmentofEnergyreporthighlightsthematerialsthatcouldbesubjecttogreaterUSsupportinfurtheranceofthegoalofdevelopingUSproductionpotential,andthefollowinggraphicishelpfultobetterunderstandthewiderangeofmaterials
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TheEvolutionofWarfare:RecentStatementsbyUSOfficials
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Source:MorganStanleyResearch
•WarDepartmentAIAccelerationblueprint:“WemustinternalizethatMilitaryAIisgoingtobearacefortheforeseeablefuture,andthereforespeedwins…robustcompetitionbysmallteams,withtransparentmetricsforresults,istheengineofcommercialAIleadership.”
•DoWSecretaryHegseth,Jan.12speech:“Weneedinnovationtocomefromanywhereandevolvewithspeedandpurpose…[DoWCTOEmilMichaelwillreporttohim]everyday,andfrankly,onwhetherweare[winning]orlosingthetechnologyandinnovationcompetition.”
•DoWCTOEmilMichael:“Thesesixcriticaltechnologyareasrepresenttheprioritiesthatwilldeliverthegreatestimpact,thefastestresultsandthemostdecisiveadvantageonthebattlefield.”The6technologyareasare:
1.AppliedAI(pervasiveuseacrossDoW)
2.Biomanufacturing(domesticmanufacturingofmilitarycomponentsbyharnessinglivingsystems)
3.ContestedLogisticsTechnologies(ensuringseamlesssupplychainsincontestedenvironments)
4.Quantumandbattlefieldinformationdominance
5.Scaledhypersonics(massproductionofhypersonicmissiles)
6.Scaleddirectedenergy(microwavesandlasers,primarilyforuseasanti-dronedefense)
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Prediction#4:AITechTransferand“GrossDomesticIntelligence”
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Source:MorganStanleyResearch
•InresponsetoPr
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