Citric-acid-d4-trisodium-Sodium-citrate-d-sub-4-sub-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemECitricacid-d4trisodiumCat.No.:HY-W724319CASNo.:2704-20-3Synonyms:Sodiumcitrate-d4;Trisodiumcitrateanhydrous-d4分⼦式:C₆HD₄Na₃O₇分⼦量:262.09作⽤靶点:Isotope-LabeledCompounds;EndogenousMetabolite;Bacterial;Apoptosis作⽤通路:Others;MetabolicEnzyme/Protease;Anti-infection;Apoptosis储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性Citricacid-d4trisodium(Sodiumcitrate-d4)氘代标记的Citricacidtrisodium(HY-B2201)。Citricacidtrisodium(Sodiumcitrate)⼀种防腐剂和⾷品添加剂。Citricacidtrisodium诱导HaCaT细胞凋亡(apoptosis)，细胞周期阻滞于G2/M期和S期。Citricacidtrisodium通过降低抗氧化酶活性引起肝脏氧化损伤。Citricacidtrisodium也⼀种酸化剂、乳化剂、螯合剂和缓冲剂，⼴泛应⽤于许多⾏业。体外研究Stableheavyisotopesofhydrogen,carbon,andotherelementshavebeenincorporatedintodrugmolecules,largelyastracersforquantitationduringthedrugdevelopmentprocess.Deuterationhasgainedattentionbecauseofitspotentialtoaffectthepharmacokineticandmetabolicprofilesofdrugs.REFERENCES[1].CiriminnaR,etal.Citricacid:emergingapplicationsofkeybiotechnologyindustrialproduct.ChemCentJ.2017Mar8;11:22.[2].ChenX,etal.Studyoninjuryeffectoffoodadditivecitricacidonlivertissueinmice.Cytotechnology.2014Mar;66(2):275-82.[3].ChenX,LvQ,LiuY,DengW.Effectsofthefoodadditive,citricacid,onkidneycellsofmice.BiotechHistochem.2015Jan;90(1):38-44.[4].YingTH,etal.Citricacidinducescell-cyclearrestandapoptosisofhumanimmortalizedkeratinocytecellline(HaCaT)viacaspase-andmitochondrial-dependentsignalingpathways.AnticancerRes.2013Oct;33(10):4411-20.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;