Pyridoxal-5-phosphate-hydrate-Standard-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemEPyridoxal5'-phosphatehydrate(Standard)Cat.No.:HY-W011727RCASNo.:853645-22-4分⼦式:C₈H₁₀NO₆P分⼦量:247.14作⽤靶点:ReferenceStandards;EndogenousMetabolite;Amyloid-β;ERK作⽤通路:Others;MetabolicEnzyme/Protease;NeuronalSignaling;MAPK/ERKPathway;StemCell/Wnt储存⽅式:PleasestoretheproductundertherecommendedconditionsintheCertificateofAnalysis.BIOLOGICALACTIVITY⽣物活性Pyridoxal5'-phosphate(hydrate)(Standard)Pyridoxal5'-phosphate(hydrate)(HY-W011727)的分析标准品。本产品⽤于研究及分析应⽤。Pyridoxal5'-phosphatehydrate维⽣素B6的活性形式，它多种酶(包括可催化神经递质多巴胺和5-羟⾊胺⽣产的最后阶段的芳族L-氨酸脱羧酶)的重辅因⼦。Pyridoxal5'-phosphatehydrate维⽣素B6REFERENCES[1].AllenGF,etal.Pyridoxal5'-phosphatedeficiencycausesalossofaromaticL-aminoaciddecarboxylaseinpatientsandhumanneuroblastomacells,implicationsforaromaticL-aminoaciddecarboxylaseandvitaminB(6)deficiencystates.JNeurochem.2010Jul;114(1):87-96.[2].Calderón-OspinaCA,etal.BVitaminsinthenervoussystem:Currentknowledgeofthebiochemicalmodesofactionandsynergiesofthiamine,pyridoxine,andcobalamin.CNSNeurosciTher.2020Jan;26(1):5-13.‑Junpathway.MolMedRep.2013Oct;8(4):973-8.DiseaseMouseModel.Antioxidants(Basel).2022Mar21;11(3):601.[5].ZhangL,etal.,Pyridoxine5'-phosphateoxidaseisanoveltherapeutictargetandregulatedbytheTGF-βsignallingpathwayinepithelialovariancancer.CellDeathDis.2017Dec13;8(12):3214.[6].NakamuraS,etal.,Pyridoxalphosphatepreventsprogressionofdiabeticnephropathy.NephrolDialTransplant.2007Aug;22(8):2165-74.McePdfHeight1/1MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemECaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792;02