Sotolone-Dimethylhydroxyfuranone-生命科学试剂-MCE

Hotline:400-820-3792Inhibitors•ScreeningLibraries•Proteinswww.MedChemESotoloneCat.No.:HY-W021008CASNo.:28664-35-9Synonyms:Dimethylhydroxyfuranone分⼦式:C₆H₈O₃分⼦量:128.13作⽤靶点:Fungal作⽤通路:Anti-infection储存⽅式:Pureform-20°C3years4°C2yearsInsolvent-80°C6months-20°C1month溶解性数据体外实验DMSO:100mg/mL(780.46mM;Needultrasonic)MassSolvent1mg5mg10mgConcentration制备储备液1mM7.8046mL39.0229mL78.0457mL5mM1.5609mL7.8046mL15.6091mL10mM0.7805mL3.9023mL7.8046mL请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液；⼀旦配成溶液，请分装保存，避免反复冻融造成的产品失效。储备液的保存⽅式和期限：-80°C,6months;-20°C,1month。-80°C储存时，请在6个⽉内使⽤，-20°C储存时，请在1个⽉内使⽤。BIOLOGICALACTIVITY⽣物活性Sotolone(Dimethylhydroxyfuranone)⼀种⼿性芳⾹化合物，具有独特的焦糖、咖喱、核桃和中草药般的⽓味。Sotolone可激活⼈嗅觉受体OR8D1，其S对映体和R对映体的EC50分别为84.98和167.2μM。Sotolone在体外可对稻瘟病表现出中等程度的抑制活性。1/2MasterofBioactiveMolecules—您⾝边的抑制剂⼤师www.MedChemEREFERENCES[1].LeDangQ,etal.InvitroandinvivoantimicrobialactivitiesofextractsandconstituentsderivedfromDesmodiumstyracifolium(Osb.)Merr.againstvariousphytopathogenicfungiandbacteria.IndustrialCropsandProducts.2022Nov15;188:115521.[2].WangJ,etal.DecodingMolecularMechanismUnderlyingHumanOlfactoryReceptorOR8D1ActivationbySotoloneEnantiomers.JAgricFoodChem.2024Mar13;72(10):5403-5415.McePdfHeightCaution:Producthasnotbeenfullyvalidatedformedicalapplications.Forresearchuseonly.Tel:400-820-3792ax:021