版权说明:本文档由用户提供并上传,收益归属内容提供方,若内容存在侵权,请进行举报或认领
文档简介
1、Sleep medication linked to bizarre behaviourNew evidence has linked a commonly prescribed sleep medication with bizarre behaviours, including a case in which a woman painted her front door in her sleep.UK and Australian health agencies have released information about 240 cases of odd occurrences, in
2、cluding sleepwalking, amnesia and hallucinations among people taking the drug zolpidem.While doctors say that zolpidem can offer much-needed relief for people with sleep disorders, they caution that these newly reported cases should prompt a closer look at its possible side effects.Zolpidem, sold un
3、der the brand names Ambien, Stilnoct and Stilnox, is widely prescribed to treat insomnia and other disorders such as sleep apnea. Various forms of the drug, made by French pharmaceutical giant Sanofi-Aventis, were prescribed 674,500 times in 2005 in the UK.A newly published report from Australias Fe
4、deral Health Department describes 104 cases of hallucinations and 62 cases of amnesia experienced by people taking zolpidem since marketing of the drug began there in 2000. The health department report also mentioned 16 cases of strangesleepwalking by people taking the medication.Midnight snackIn on
5、e of these sleepwalking cases a patient woke with a paintbrush in her hand after painting the front door to her house. Another case involved a woman who gained 23 kilograms over seven months while taking zolpidem. “It was only when she was discovered in front of an open refrigerator while asleep tha
6、t the problem was resolved,” according to the report.The UKs Medicines and Healthcare products Regulatory Agency, meanwhile, has recorded 68 cases of adverse reactions to zolpidem from 2001 to 2005.The newly reported cases in the UK and Australia add to a growing list of bizarre sleepwalking episode
7、s linked to the drug in other countries, including reports of people sleep-driving while on the medication. In one case, a transatlantic flight had to be diverted after a passenger caused havoc after taking zolpidem.Hypnotic effectsThere is no biological pathway that has been proven to connect zolpi
8、dem with these behaviours. The drug is a benzodiazepine-like hypnotic that promotes deep sleep by interacting with brain receptors for a chemical called gamma-aminobutyric acid. While parts of the brain become less active during deep sleep, the body can still move, making sleepwalking a possibility.
9、The product information for prescribers advises that psychiatric adverse effects, including hallucinations, sleepwalking and nightmares, are more likely in the elderly, and treatment should be stopped if they occur.Patient advocacy groups say they would like government health agencies and drug compa
10、nies to take a closer look at the possible risks associated with sleep medicines. They stress that strange sleepwalking and sleep-driving behaviours can have risky consequences.“When people do something in which theyre not in full control its always a danger,” says Vera Sharav of the New York-based
11、Alliance for Human Research Protection, a US network that advocates responsible and ethical medical research practices.Tried and tested“The more reports that come out about the potential side effects of the drug, the more research needs to be done to understand if these are real side effects,” says
12、sleep researcher Kenneth Wright at the University of Colorado in Boulder, US.Millions of people have taken the drug without experiencing any strange side effects, points out Richard Millman at Brown Medical School, director of the Sleep Disorders Center of Lifespan Hospitals in Providence, Rhode Isl
13、and, US. He says that unlike older types of sleep medications, zolpidem does not carry as great a risk of addiction.And Wright notes that some of the reports of “sleep-driving” linked to zolpidem can be easily explained: some patients have wrongly taken the drug right before leaving work in hopes th
14、at the medicine will kick in by the time they reach home. Doctors stress that the medication should be taken just before going to bed.The US Food & Drug Administration says it is continuing to actively investigate and collect information about cases linking zolpidem to unusual side effects.The Ambie
15、n label currently lists strange behaviour as a “special concern” for people taking the drug. “Its a possible rare adverse event,” says Sanofi-Aventis spokesperson Melissa Feltmann, adding that the strange sleepwalking behaviours “may not necessarily be caused by the drug” but instead result from an
16、underlying disorder. She says that “the safety profile of zolpidem is well established”. The drug received approval in the US in 1993.Questions 1-6Do the following statements agree with the information given in the reading passage?In boxes 1-6 on your answer sheet writeTRUE if the statement is true
17、according to the passageFALSE if the statement is false according to the passageNOT GIVEN if the information is not given in the passage1. Ambien, Stilnoct and Stilnox are brand names of one same drug treating insomnia.2. The womans obesity problem wasnt resolved until she stopped taking zolpidem.3.
18、 Zolpidem received approval in the UK in 2001.4. The bizarre behaviour of a passenger after taking zolpidem resulted in the diversion of a flight bound for the other side of the Atlantic.5. Zolpidem is the only sleep medication that doesnt cause addiction.6. The sleep-driving occurrence resulted fro
19、m the wrong use of zolpidem by an office worker.Question 7-9Choose the appropriate letters A-D and Write them in boxes 7-9 on your answer sheet.7. How many cases of bizarre behaviours are described in an official report from Australia?A. 68B. 104C. 182D. 2408. Which of the following is NOT mentioned
20、 in the product information about zolpidem?A. Treatment should be stopped if side effects occur.B. Medication should be taken just before going to bed.C. Adverse effects are more likely in the elderly.D. Side effects include nightmares, hallucinations and sleepwalking.9. Who claimed that the safety
21、description of zolpidem was well established?A. Kenneth WrightB. Melissa FeltmannC. Richard MillmanD. Vera SharavQuestions 10-13Answer the following questions with NO MORE THAN THREE WORDS each in boxes 10-13.10. How many times was French-made zolpidem prescribed in 2005 in Britain?11. What kind of
22、hypnotic is zolpidem as a drug which promotes deep sleep in patients?12. What can sleepwalking and sleep-driving behaviours cause according to patient advocacy groups?13. What US administration says that it has been investigating the cases relating zolpidem to unusual side effects?Answer keys and ex
23、planations:1. TrueSee para.3 from the beginning: Zolpidem, sold under the brand names Ambien, Stilnoct and Stilnox, is widely prescribed to treat insomnia and other disorders such as sleep apnea.2. FalseSee para.1 under the subtitle “Midnight snack”: Another case involved a woman who gained 23 kilog
24、rams over seven months while taking zolpidem. “It was only when she was discovered in front of an open refrigerator while asleep that the problem was resolved”3. Not GivenSee para.2 under the subtitle “Midnight snack”: The UKs Medicines and Healthcare products Regulatory Agency, meanwhile, has recor
25、ded 68 cases of adverse reactions to zolpidem from 2001 to 2005. (The time the drug was approved in the UK was not mentioned.)4. TrueSee para.3 under the subtitle “Midnight snack”: In one case, a transatlantic flight had to be diverted after a passenger caused havoc after taking zolpidem.5. FalseSee
26、 para.2 under the subtitle “Tried and tested”: He says that unlike older types of sleep medications, zolpidem does not carry as great a risk of addiction.6. Not GivenSee para.3 under the subtitle “Tried and tested”: And Wright notes that some of the reports of “sleep-driving” linked to zolpidem can
27、be easily explained: some patients have wrongly taken the drug right before leaving work in hopes that the medicine will kick in by the time they reach home. (No patients as office workers are mentioned in the passage.)7. CSee para.4 from the beginning: A newly published report from Australias Feder
28、al Health Department describes 104 cases of hallucinations and 62 cases of amnesia experienced by people taking zolpidem since marketing of the drug began there in 2000. The health department report also mentioned 16 cases of strange sleepwalking by people taking the medication.8. BSee the sentence
29、in para.2 under the subtitle “Hypnotic effects” (The product information for prescribers advises that psychiatric adverse effects, including hallucinations, sleepwalking and nightmares, are more likely in the elderly, and treatment should be stopped if they occur.) and the sentence in para.3 under the subtitle “Tried and tested” (Doctors “not the product information” stress that the medication should be taken just before going to bed.)9. BSee para.5 under the s
温馨提示
- 1. 本站所有资源如无特殊说明,都需要本地电脑安装OFFICE2007和PDF阅读器。图纸软件为CAD,CAXA,PROE,UG,SolidWorks等.压缩文件请下载最新的WinRAR软件解压。
- 2. 本站的文档不包含任何第三方提供的附件图纸等,如果需要附件,请联系上传者。文件的所有权益归上传用户所有。
- 3. 本站RAR压缩包中若带图纸,网页内容里面会有图纸预览,若没有图纸预览就没有图纸。
- 4. 未经权益所有人同意不得将文件中的内容挪作商业或盈利用途。
- 5. 人人文库网仅提供信息存储空间,仅对用户上传内容的表现方式做保护处理,对用户上传分享的文档内容本身不做任何修改或编辑,并不能对任何下载内容负责。
- 6. 下载文件中如有侵权或不适当内容,请与我们联系,我们立即纠正。
- 7. 本站不保证下载资源的准确性、安全性和完整性, 同时也不承担用户因使用这些下载资源对自己和他人造成任何形式的伤害或损失。
最新文档
- 2026年11月01日 怀化市鹤城区考核基地 大冢制药 市场推广专员 16人
- 2026年华阳集团招聘试题题库及答案
- 贵州省六盘水市盘州市2025-2026学年大象版六年级上学期期末考试科学试卷(有答案)
- 2026幼儿肺结核防治专题培训课件
- 2026-2027学年北师大版八年级上册数学9月份第一次质量检测(含答案)
- 2026家长汛期安全防范课件
- 中国2型糖尿病运动治疗指南要点解读
- 骨科手术机器人技术的现状与未来
- CoinGecko- 2026 Q1 加密行业报告-加密货币
- 2026新学期乡村学校德育工作计划课件:爱国主义教育
- 压力管道设计、审核人员考试题库(含答案)
- 检验科实验室安全规范培训指南
- 14.3 热机的效率 课件 2025-2026学年人教版物理九年级全一册
- 2025年广东省教师招聘考试(音乐)历年参考题库含答案详解
- 两票及三种人培训
- 1.5找规律(课件)-2025-2026学年二年级上册数学西师大版
- 学校工会采购制度
- 雨课堂学堂在线学堂云《机电系统设计与分析(重庆)》单元测试考核答案
- GB/T 48000.2-2026标准数字化第2部分:参考架构模型
- 统编版一年级上册道德与法治《第5课-老师您好!-(第1课时)》教学课件
- 玉米肥料基础知识培训课件
评论
0/150
提交评论