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Melanoma Screening and MelaFind Sam Karnes BME 281 Melanoma UV ray exposure damages DNA of skin cells Cancer cells Grow without control Invade surrounding tissues (metastasize) Tumors Cancerous vs. Benign Most Deadly Form of Skin Cancer but treatable if identified early Mela Sciences Inc Became a part of Electro-Optical Sciences 1989 R&D projects for the Department of Defense remote sensing and image analysis Mid 1990s Worked with NYU Applied signal processing techniques towards medical applications Developed DIFOTI, SkinSurf, SLIM, and MelaFind MelaFind Provides dermatologist more information when considering a biopsy Composed of Illuminator Blue to near infrared Lens System Photon Sensor Identifies cancerous skin lesions Algorithms that automatically analyze results Results 1632 lesions for analysis 175 lesions were identified as positive Overall the device showed that 98.3% were melanoma (172/175) Device discovered 10.8% of the negative class lesions Dermatologists in the study only found 5.6%. Avoidable biopsies reduced by 90% Advantages Reduces skin cancer fatalities Reduces biopsy procedures Reduced costs No adverse side effects Approved for pre-market use in U.S. and approved for sale in European Union Results are extremely accurate Disadvantages Not covered by insurance Isopropyl alcohol used in lesion preparation can cause skin irritation Not yet available to the general population Costs MelaFind costs $7,500 Includes placement and training Cost per patient $50 per lesion or $150 for multiple lesions Cost of biopsy Between $150 and $1000 Future of MelaFind Could be publically available Reduce size and price Help patients with medical history of skin cancer Insurance Coverage References “About MelaFind.“ MELA Sciences. MELA Sciences Inc, 2012. Web. . Corley, Gavin. MelaFind Device. Digital image. MelaFind Lesion Imaging Device Receives CE Marking. N.p., n.d. Web. . Greenhalgh, Emily. +Mass Device. Massachusetts Medical Devices Journal, 3 Nov. 2011. Web. . Gutkowicz-Krusin, Dina. JAMA Dermatology 147.2 (2011): 188-94. Print. “How MelaFind Uses Military Tech To Find Cancer.“ Co.Exist. Ed. Morgan Clendaniel. Fast Company and Inc, n.d. Web. . “How Much Does A Biopsy Cost?“ CostE. N.p., n.d. Web. . Landro, Laura. Wall Street Journal. Dow Jones and Company, 2 Sept. 2013. Web. . “MelaFin