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初级级医疗疗中评评估及治疗疗 失眠症 2013年8月18日星期日 关于作者 Karen Falloon 是博士研究生,Bruce Arroll 是教授和 科室主任,C Raina Elley 是副教授,他们都在新西兰 奥克兰大学全科医学和初级卫生保健科工作。 Antonio Fernando III 是新西兰奥克兰大学心理医学 系的高级讲师。 致谢 本单元是根据 BMJ 的教育文献撰写完成。BMJ Learning 的临床编辑人员编辑了原始文献并为本单元 增加了问题部分 BMJ 2011; 342:d2899 doi: 10.1136/bmj.d2899( 2011 年 5 月 27 日发表) 知识点摘要 累及1/3 人群 病史 继发性失眠症 白天过度嗜睡 原发性失眠症 睡眠卫生技术 限制卧床时间 行为干预措施 镇静剂治疗 最后 前言 失眠症累及 1/3 的一般人群 失眠症的患病率为 10%-50% 失眠症定义 与生理健康和精神健康状况下降相关 镇静剂治疗 但睡眠的正常时间范围 7-9 个小时 尽管有充足的时间和机会睡 觉,仍然反复发作入睡困 难、睡眠难以持续和睡眠不 安或睡眠质量下降,导致日 间出现某种形式的活动障碍 并持续至少一个月。 -睡眠障碍国际分类代码手册 什么失眠症?谁谁会患上失眠症? 主诉 入睡困难 很难保持睡眠状态 经常醒来 早醒后无法继续入睡 睡醒后仍感到疲倦 原发性30:274-80. Arroll B, Fernando A, Falloon K, Warman G, Goodyear-Smith F. Sleepless in Seattle? Finding patients with primary insomnia using the Auckland Sleep Questionnaire. North American Primary Care Research Group Seattle, 2010. Simon GE, VonKorff M. Prevalence, burden, and treatment of insomnia in primary care. Am J Psychiatry 1997;154:1417-23. American Sleep Disorders Association. 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Panneman MJ, Goettsch WG, Kramarz P, Herings RM. The costs of benzodiazepine-associated hospital-treated fall injuries in the EU: a Pharmo sudy. Drugs Aging 2003;20:883-9. Campbell SS, Broughton RJ. Rapid decline in body temperature before sleep: fluffing the physiological pillow? Chronobiol Int1994;11:126-31. Curran HV, Collins R, Fletcher S, Kee SC, Woods B, Illife S. Older adults and withdrawal from benzodiazepine hypnotics in general practice: effects on cognitive function, sleep, mood and quality of life. Psychological Med 2003;33:1223-37. Shapiro CM, Dement WC. Impact and epidemiology of sleep disorders. BMJ 1993;306:1604-7. Johns MW. A new method for measuring daytime sleepiness: the Epworth sleepiness scale. Sleep 1991;14:540-5. Rofail LM, Wong KH, Unger G, Marks GB, Grunstein RR. Comparison between a single-channel nasal airflow device and oximetry for the diagnosis of obstructive sleep apnea. Sleep 2010;33:1106-14. National Institute for Health and Clinical Excellence. Continuous positive airway pressure for the treatment of obstructive sleep apnoea/hypopnoea syndrome. NICE, 2008. .uk/TA139 Cooke JR, Ancoli-Israel S. Normal and abnormal sleep in the elderly. Handb Clin Neurol 2011;98:653-5. Arroll B, Goodyear-Smith F, Kerse N, Fishman T, Gunn J. Effect of the addition of a “help“ question to two screening questions on specificity for diagnosis of depression in general practice: diagnostic validity study. BMJ 2005;331:884. 参考文献 Puddifoot S, Arroll B, Goodyear-Smith FA, Kerse NM, Fishman TG, Gunn JM. A new case-finding tool for anxiety: a pragmatic diagnostic validity study in primary care. I J Psychiatry Med 2007;4:371-81. Kroenke K, Spitzer RL, Williams BW, Lowe B. A ultra-brief screening scale for anxiety and depression: the PHQ 4. Psychosomatics2009;50:613-21. Zigmond AS, Snaith RP. The hospital anxiety and depression scale. Acta Psychiatr Scand 1983;67:361-70. Mayfield D, McLeod G, Hall P. The CAGE questionnaire: validation of a new alcoholism screening instrument. Am J Psychiatry1974;131:1121-3. Wennberg P, Escobar F, Espi F, Canteras M, Lairson DR, Harlow K, et al. The alcohol use disorders identification test (AUDIT): A psychometric evaluation. Reports Dept Psychol U Stockholm 1996;811:1-14. WHO. The ASSIST projectAlcohol, Smoking and Substance Involvement Screening Test. 2011./substance_abuse/activities/assist/en/index.html Chung F, Yegneswaran B, Liao P, Chung SA, Vairavanathan S, Islam S, et al. Stop questionnaire. A tool to screen patients for obstructive sleep apnea. Anesthesiology 2008;108:812-21. Kayumov L, Brown, G, Jindal R, Buttoo K, Shapiro CM. A randomized, double-blind, placebo-controlled crossover study of the effect of exogenous melatonin on delayed sleep phase syndrome. Psychosom Med 2001;63:40-8. Rosenthal NE, Joseph-Vanderpool JR, Levendosky AA, Johnston SH, Allen R, Kelly KA, et al. Phase-shifting effects of bright morning light as treatment for delayed sleep phase syndrome. Sleep 1990;13:354-61. Best Practice. Insomnia. /best-practice/monograph/227.html Edinger JD, Olsen MK, Stechuchak KM, Means MK, Lineberger MD, Kirby A, et al. Cognitive behavioral therapy for patients with primary insomnia or insomnia associated predominantly with mixed psychiatric disorders: a randomized clinical trial. Sleep 2009;32:499-510. Morgenthaler T, Kramer M, Alessi C, Friedman L, Boehlecke B, Brown T, et al. Practice parameters for the psychological and behavioral treatment of insomnia: an update. An American academy of sleep medicine report. Sleep 2006;29:1415-9. Morin CM, Bootzin RR, Buysse DJ, Edinger JD, Espie CA, Lichstein KL, et al. Psychological and behavioral treatment of insomnia: update of the recent evidence (1998-2004). Sleep 2006;29:1398-414. Irwin MR, Cole JC, Nic

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