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2016年职称英语综合类a级阅读理解模拟题及答案eat more, weigh less, live longerclever genetic detective work may have found out the reason why a near-starvation diet prolongs the life of many animals.ronald kahn at harvard medical school in boston, us, and his colleagues have been able to extend the lifespan (寿命) of mice by 18 per cent by blocking the rodents (啮齿动物) increase of fat in specific cells. this suggests that thinnessand not necessarily dietpromotes long life in calorie (热量卡) restricted animals.its very cool work, says aging researcher cynthia kenyon of the university ofcalifornia, san francisco. these mice eat all they want, lose weight and live longer. its like heaven.calorie restriction dramatically extends the lifespan of organisms as different as worms and rodents. whether this works in humans is still unknown, partly because few people are willing to submit to such a strict diet.but many researchers hope they will be able to trigger the same effect with a drug once they understand how less food leads to a longer life. one theory is that eating less reduces the increase of harmful things that can damage cells. but kahns team wondered whether the animals simply benefit by becoming thin.to find out, they used biology tricks to disrupt the insulin (胰岛素) receptor (受体) gene in lab micebut only in their fat cells. since insulin is needed to help fat cells store fat, these animals were protected against becoming fat, explains kahn.this slight genetic change in a single tissue had dramatic effects. by three months of age, kahns modified mice had up to 70 per cent less body fat than normal control mice, despite the fact that they ate 55 per cent more food per gram of body weight.in addition, their lifespan increased. the average control mouse lived 753 days, while the thin rodents averaged a lifespan of 887 days. after three years, all the control mica had died, but one-quarter of the modified rodents were still alive.that they get these effects by just manipulating the fat cells is controversial, says leonard guarente of the massachusetts institute of technology, who studies calorie restriction and aging.but guarente says kahn has yet to prove that the same effect is responsible for increased lifespan in calorie-restricted animals. it might be the same effect or there might be two routes to long life, he points out, and that would be very interesting.11ronald kahn and his colleagues can make mice live longer byaoffering them less food.bgiving them a balanced diet.cdisrupting the specific genes in their fat cells.dpreventing them growing larger.12according to the passage, we do not know whether humans will benefit from taking in fewer calories partly becauseahumans, worms and rodents are different.bmost people are not willing to be put on a strict diet.cthe effect is not known.dgenetic changes in tissues can not be performed on humans.13what does the last sentence in the third paragraph imply?apeople like to lose weight, but they do not like to eat lessbpeople want to go to heaven, but they do not want to die.cmice will go to heaven if they lose weight.dmice enjoy losing weight.14 the average modified mouse liveda3 years.b753 days.cmore than 3 years.d887 days.15what can be inferred from the passage about the r
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