痛经和补充锌微量元素PPT课件.ppt

2019/12/14,.,痛经与补锌美国人痛经调理系列,蒋大夫,1,锌可以预防痛经,Zinctreatmentpreventsdysmenorrhea.,AuthorinformationGeorgeEbyResearch,14909-CFitzhughRoad,Austin,TX78736,UnitedStates.,2,痛经蒋大夫,摘要原发性痛经，女性月经来潮时，会产生轻，中度子宫痉挛。超过一半，有人估计在月经的第一天达到90的美国妇女经历月经来潮疼痛。大约十分之一的妇女不能因严重的子宫痉挛履行其正常的例行一至三天每次月经周期。虽然子宫收缩和放松定期发生，月经期间收缩强得多产生疼痛和“抽筋”。女性痛经有高水平的前列腺素，认为会导致月经痉挛的激素。前列腺素被认为是暂时减少或停止血液供应给子宫，从而导致肌肉收缩和缺乏氧气的子宫疼痛。人们所期望的锌，如用于治疗痉挛的非甾体类抗炎药，以减少前列腺素的产生。锌能抑制前列腺素排除这种作用机理的代谢，提示缺锌会导致抽筋。然而，它表明足量的锌，30毫克剂量每天。一到四天发病前月经给出，基本上可以防止所有对月经的所有警告和所有的经痛。,3,痛经,一个假设为作用机理的是，前体（COX-2）或前列腺素代谢物会导致月经痉挛和未前列腺素本身。另一种假说是，锌在子宫的抗氧化和抗炎作用。改善微血管循环锌可能有助于防止抽筋和疼痛。在每天消耗锌31毫克的患者，经前期紧张（PMT）的症状并没有出现，而在消耗15毫克的锌病人，PMT症状确实发生（P0.001）。使用30毫克的锌一次至每天3次，为一至四天紧接月经预防痛经协议描述和它们被推荐用于进一步的研究。从没有因锌处理未决月经的所有警告的副作用是有可能怀孕的担忧。美国RDA的锌显得过于低，以优化妇女的健康和防止月经来潮。,4,痛经蒋大夫美国人如何调理痛经,Primarydysmenorrhea,menstrualcrampsinotherwisewellwomen,producesmildtodebilitatingcrampingoftheuterus.Morethanhalf,andbysomeestimates90%ofallAmericanwomenexperiencemenstrualcrampsduringthefirstseveraldaysofmenstruation.Aboutoneintenwomenareunabletoperformtheirnormalroutineforonetothreedayseachmenstrualcycleduetosevereuterinecramping.,5,痛经蒋大夫,Althoughtheuteruscontractsandrelaxesroutinely,duringmenstruationthecontractionsaremuchstrongerproducingpainandcramps.Womenwithdysmenorrheahavehighlevelsofprostaglandins,hormonesbelievedtocausemenstrualcramping.Prostaglandinsarebelievedtotemporarilyreduceorstopbloodsupplytotheuterus,thusdeprivingtheuterusofoxygenresultingincontractionsandpain.,6,痛经蒋大夫美国人如何调理痛经,Onewouldexpectzinc,likethenon-steroidalanti-inflammatorydrugsusedtotreatcramping,toreducetheproductionofprostaglandins.Zincinhibitsthemetabolismofprostaglandinsrulingoutthismechanismofaction,suggestingerroneouslythatzincdeficiencywouldpreventcramping.However,itisshownbycasehistoriesthatzinc,in1-330-mgdosesgivendailyforonetofourdayspriortoonsetofmenses,preventsessentiallyalltoallwarningofmensesandallmenstrualcramping.Onehypothesisforamechanismofactionisthataprecursor(COX-2)ormetaboliteofprostaglandinscausesmenstrualcrampingandnotprostaglandinsthemselves.,7,美国人如何调理痛经,Anotherhypothesisisthatzinchasantioxidantandanti-inflammatoryactionsintheuterus.Improvementinmicro-vesselcirculationbyzincmayhelppreventcrampingandpain.Inpatientsconsuming31mgofzincperday,premenstrualtension(PMT)symptomsdidnotoccur,whileinpatientsconsuming15mgofzinc,PMTsymptomsdidoccur(P0.001).onetofourdaysimmediatelypriortomensestopreventdysmenorrheaaredescribedandtheyarerecommendedforadditionalstudy.,8,痛经美国人如何调理痛经,TheUnitedStatesRDAforzincappearstobetoolowtooptimizeProtocolsusing30mgofzinconcetothreetimesadayforwomenshealthandpreventmenstrualcramps.Thesideeffectfromtheabsenceofallwarningofpendingmensesduetozinctreatmentwasconcernofpossib