抗菌药物DDD值及各种指标计算方法.doc

山西省卫生厅关于印发抗菌药物临床应用相关指标计算公式的通知 晋卫办医政201139号各市卫生局、厅直厅管医疗机构：为贯彻落实卫生部关于做好全国抗菌药物临床应用专项整治活动的通知（卫办医政发201156号）精神，确保全省抗菌药物临床应用相关指标与数据计算的科学、准确和统一，现将抗菌药物临床应用指标计算方法印发给你们，并将有关事宜通知如下:一、各级卫生行政部门及医疗机构要高度重视，责成专人负责，熟悉和掌握相关内容，准确调查和计算相关数据与指标，并有效利用相关数据指导和干预抗菌药物的临床应用。二、为方便全省医疗机构计算抗菌药DDDs，使其具有较好的可比性，全省抗菌药物DDD值均采用附件二提供数据。三、儿童医院抗菌药物DDD值暂以成人1/3来计算。四、医疗机构要按照山西省卫生厅2011年抗菌药物临床应用专项整治活动工作方案要求及时上报相关指标与数据。对不能及时上报或弄虚作假的医疗机构，一经查实，严肃处理。联 系 人：省卫生厅医政处 牛晓辉 刘玉伟 范惠霞联系电话 真子邮箱：附件一 药物临床应用相关指标计算公式附件二 成人抗菌药物DDD值附件三 抗菌药物相关指标与数据统计表格二一一年五月二十五日附件一 药物临床应用相关指标计算公式一、处方指标（Prescription indicators）。1.每次就诊人均用药品种数表达方式：2.每次就诊人均药费表达方式：3.就诊使用抗菌药物的百分率表达方式： 4.就诊使用注射药物的百分率表达方式： 5.基本药物占处方用药的百分率表达方式：二、抗菌药物用药指标（Indicators of antimicrobial drugs use）。1.住院患者人均使用抗菌药物品种数表达方式：2.住院患者人均使用抗菌药物费用表达方式：3.住院患者使用抗菌药物的百分率表达方式： 4DDDs（用药频度）表达方式： 某药一定时期销售总量：是指对同一品种、不同规格、不同厂家，分别计算同期其销售总量（g)，最后求和得到该品种消耗的总量（g）DDD(defined daily dose)：成人限定日剂量。5.抗菌药物使用强度表达方式： 如计算某医院抗菌药物使用强度，它的抗菌药物消耗量（累计DDD数）即为该医院住院患者消耗的所有抗菌药物DDDs相加；计算某科室抗菌药物使用强度，它的抗菌药物消耗量（累计DDD数）为该科室消耗的所有抗菌药物DDDs相加。 同期收治患者人天数=同期出院患者人数同期住院患者平均住院天数6.抗菌药物费用占药费总额的百分率表达方式： 7.抗菌药物特殊品种使用量占抗菌药物使用量的百分率表达方式：8.住院用抗菌药物患者病原学检查百分率表达方式： （三）外科清洁手术预防用药指标(Antimicrobial drugs use indicator of perioperative clean incision)。1.清洁手术预防用抗菌药物百分率表达方式：2.清洁手术预防用抗菌药物人均用药天数表达方式：3.接受清洁手术者，术前0.5-2.0小时内给药百分率表达方式：4.重点外科手术前0.5-2.0小时内给药百分率 （1）髋关节置换术前0.5-2.0小时内给药百分率表达方式： （2）膝关节手术前0.5-2.0小时内给药百分率表达方式： （3）子宫肌瘤切除术前0.5-2.0小时内给药百分率表达方式：附件二 成人抗菌药物DDD值 药品名称 规格单位单剂量剂量单位DDD值单位DDD青霉素钠注射剂1.6MU支1.600 MU克3.6g青霉素钠注射剂4MU支4.000 MU克3.6g青霉素钠注射剂0.8MU支0.800 MU克3.6g青霉素片0.125g片0.125 g克2.0g青霉素片0.25g片0.250 g克2.0g苯唑西林钠注射剂0.5g支0.500 g克2.0g苯唑西林钠注射剂1.0g支1.000 g克2.0g氯唑西林胶囊0.125g粒0.125 g克2.0g氯唑西林胶囊0.25g粒0.250 g克2.0g氯唑西林胶囊0.5g粒0.500 g克2.0g氯唑西林颗粒剂50mg包50.000 mg克2.0g氯唑西林注射剂0.5g支0.500 g克2.0g氟氯西林胶囊0.125g片0.125 g克2.0g氟氯西林注射剂0.5g支0.500 g克2.0g氟氯西林注射剂1.0g支1.000 g克2.0g氨苄西林钠胶囊0.25g粒0.250 g克2.0g氨苄西林钠注射剂0.5g支0.500 g克2.0g阿莫西林胶囊0.25g粒0.250 g克1.0g阿莫西林胶囊0.5g粒0.500 g克1.0g阿莫西林干糖浆125mg袋125.000 mg克1.0g阿莫西林颗粒125mg袋125.000 mg克1.0g阿莫西林注射剂0.5g支0.500 g克1.0g阿莫西林注射剂2.0g支2.000 g克1.0g阿莫西林片0.25g片0.250 g克1.0g哌拉西林钠注射剂0.5g支0.500 g克14.0g哌拉西林钠注射剂1.0g支1.000 g克14.0g哌拉西林钠注射剂2.0g支2.000 g克14.0g哌拉西林钠注射剂3.0g支3.000 g克14.0g替卡西林钠注射剂1.0g支1.000 g克15.0g替卡西林钠注射剂3.0g支3.000 g克15.0g替卡西林钠注射剂6.0g支6.000 g克15.0g美西林钠注射剂0.5g支0.500 g克1.2g美西林钠注射剂1.0g支1.000 g克1.2g美洛西林钠注射剂1.0g支1.000 g克6.0g美洛西林钠注射剂2.0g支2.000 g克6.0g阿洛西林钠注射剂1.0g支1.000 g克12.0g阿洛西林钠注射剂2.0g支2.000 g克12.0g阿洛西林钠注射剂3.0g支3.000 g克12.0g阿洛西林钠注射剂4.0g支4.000 g克12.0g普鲁卡因青霉素注射剂0.4MU支0.400 MU克0.6g普鲁卡因青霉素注射剂0.8MU支0.800 MU克0.6g苄星青霉素注射剂1.2MU支1.200 MU克3.6g羧苄西林钠注射剂1.0g支1.000 g克12.0g磺苄西林钠注射剂1.0g支1.000 g克15.0g磺苄西林钠注射剂2.0g支2.000 g克15.0g磺苄西林钠注射剂5.0g支5.000 g克15.0g呋布西林钠注射剂0.5g支0.500 g克6.0g奈夫西林钠胶囊0.25g粒0.250 g克3.0g奈夫西林注射剂1.0g支1.000 g克5.0g双氯西林钠胶囊0.25g粒0.250 g克2.0g阿帕西林钠注射剂1.0g支1.000 g克8.0g阿扑西林钠注射剂0.5g支0.500 g克3.0g匹美西林钠胶囊0.25g粒0.250 g克0.6g仑氨西林片0.25g粒0.250 g克0.8g阿莫西林氟氯西林胶囊0.25g粒0.250 g克1.5g阿莫西林氟氯西林钠注射剂0.5g支0.500 g克5.0g氨苄西林氯唑西林钠注射剂0.5g支0.500 g克3.0g氨苄西林氯唑西林钠注射剂1.0g支1.000 g克3.0g阿莫西林双氯西林钠胶囊0.375g粒0.375 g克1.125g氨苄西林丙磺舒胶囊0.25g粒0.250 g克2.25g氨苄西林舒巴坦注射剂0.125g支0.125 g克2.0g氨苄西林舒巴坦注射剂0.75g支0.750 g克2.0g氨苄西林舒巴坦注射剂1.5g支1.500 g克2.0g氨苄西林舒巴坦注射剂3.0g支3.000 g克2.0g氨苄西林舒巴坦片0.125g片0.125 g克1.5g氨苄西林舒巴坦片0.25g片0.250 g克1.5g氨苄西林舒巴坦片0.375g片0.375 g克1.5g阿莫西林钠舒巴坦钠注射剂0.75g支0.750 g克3.0g阿莫西林钠舒巴坦钠注射剂1.5g支1.500 g克3.0g阿莫西林钠舒巴坦钠注射剂3.0g支3.000 g克3.0g阿莫西林钠舒巴坦钠混悬剂0.25g:60ml瓶0.250 g克1.0g阿莫西林钠舒巴坦钠混悬剂0.5g:60ml瓶0.500 g克1.0g阿莫西林钠舒巴坦钠片0.5g片0.500 g克1.0g阿莫西林钠舒巴坦钠片1.0g片1.000 g克1.0g美洛西林钠舒巴坦钠注射剂0.625g支0.625 g克7.5g美洛西林钠舒巴坦钠注射剂1.25g支1.250 g克7.6g美洛西林钠舒巴坦钠注射剂2.5g支2.500 g克7.7g美洛西林钠舒巴坦钠注射剂3.75g支3.750 g克7.8g哌拉西林钠他唑巴坦钠注射剂0.5625g支0.562 g克14.0g哌拉西林钠他唑巴坦钠注射剂1.125g支1.125 g克14.0g哌拉西林钠他唑巴坦钠注射剂2.25g支2.250 g克14.0g哌拉西林钠他唑巴坦钠注射剂4.5g支4.500 g克14.0g阿莫西林克拉维酸钾干糖浆1.0g:156.25mg瓶0.457 g克1.0g阿莫西林克拉维酸钾干糖浆1.5g:228.5mg瓶1.500 g克1.0g阿莫西林克拉维酸钾干糖浆2.0g:156.25mg瓶1.870 g克1.0g阿莫西林克拉维酸钾颗粒剂156.25mg包156.250 mg克1.0g阿莫西林克拉维酸钾颗粒剂187.5mg包187.500 mg克1.0g阿莫西林克拉维酸钾颗粒剂228.5mg包228.500 mg克1.0g阿莫西林克拉维酸钾注射剂0.6g支0.600 g克3.0g阿莫西林克拉维酸钾注射剂1.2g支1.200 g克3.0g阿莫西林克拉维酸钾片0.2285g片0.228 g克1.0g阿莫西林克拉维酸钾片0.25g片0.250 g克1.0g阿莫西林克拉维酸钾片0.375g片0.375 g克1.0g阿莫西林克拉维酸钾片0.457g片0.457 g克1.0g阿莫西林克拉维酸钾片0.5625g片0.563 g克1.0g阿莫西林克拉维酸钾片0.625g片0.625 g克1.0g替卡西林克拉维酸钾注射剂1.6g支1.600 g克15.0g替卡西林克拉维酸钾注射剂3.2g支3.200 g克15.0g哌拉西林钠舒巴坦钠注射剂1.25g支1.250 g克14.0g哌拉西林钠舒巴坦钠注射剂1.5g支1.500 g克14.0g哌拉西林钠舒巴坦钠注射剂2.5g支2.500 g克14.0g舒他西林片0.125g片0.125 g克1.5g舒他西林片0.375g片0.375 g克1.5g头孢氨苄胶囊0.25g粒0.250 g克2.0g头孢氨苄颗粒剂1.0g:0.5g包1.000 g克2.0g头孢氨苄片0.25g片0.250 g克2.0g头孢唑林钠注射剂0.5 g支0.500 g克3.0g头孢唑林钠注射剂1.0g支1.000 g克3.0g头孢羟氨苄胶囊0.125g粒0.125 g克2.0g头孢羟氨苄胶囊0.25g粒0.250 g克2.0g头孢拉定胶囊0.25g粒0.250 g克2.0g头孢拉定胶囊0.5g粒0.500 g克2.0g头孢拉定干混悬剂0.125g包0.125 g克2.0g头孢拉定干混悬剂0.25g包0.250 g克2.0g头孢拉定注射剂0.5g支0.500 g克2.0g头孢拉定注射剂1.0g支1.000 g克2.0g头孢噻吩注射剂0.5g支0.500 g克4.0g头孢噻吩注射剂1.0g支1.000 g克4.0g头孢噻吩注射剂3.0g支3.000 g克4.0g头孢噻啶注射剂0.5g支0.500 g克3.0g头孢噻啶注射剂1.0g支1.000 g克3.0g头孢硫脒注射剂0.5g支0.500 g克3.0g头孢硫脒注射剂1.0g支1.000 g克3.0g头孢硫脒注射剂2.0g支2.000 g克3.0g头孢乙氰注射剂0.5g支0.500 g克4.0g头孢乙氰注射剂1.0g支1.000 g克4.0g头孢替唑钠注射剂0.5g支0.500 g克6.0g头孢替唑钠注射剂1.0g支1.000 g克6.0g头孢沙定胶囊0.25g粒0.250 g克0.75g头孢沙定干糖浆1.0g包1.000 g克0.75g头孢匹林注射剂0.5g支0.500 g克4.0g头孢匹林注射剂1.0g支1.000 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g克3.0g氯霉素胶囊0.05g支0.050 g克3.0g氯霉素滴眼液0.02g:8ml支0.020 g克氯霉素注射液0.25g支0.250 g克3.0g氯霉素阴道片0.05g片0.050 g克复方氯霉素洗剂100ml瓶100.000 ml甲砜霉素片0.25g片0.250 g克1.5g四环素眼膏2.0g支2.000 g克四环素可的松软膏2.0g支2.000 g克四环素片0.25g片0.250 g克1.0g土霉素片0.25g片0.250 g克1.0g多西环素注射剂0.1g支0.100 g克0.1g多西环素片0.1g片0.100 g克0.1g米诺环素胶囊0.05g粒0.050 g克0.2g米诺环素片0.05g片0.050 g克0.2g米诺环素片0.1g片0.100 g克0.2g胍甲环素片0.1g片0.100 g克1.2g美他环素片0.1g片0.100 g克0.6g红霉素注射剂0.25g支0.250 g克1.0g红霉素注射剂0.3g支0.300 g克1.0g红霉素软膏10.0g支10.000 g克红霉素软膏4.0g支4.000 g克红霉素眼膏2.0g支2.000 g克红霉素眼膏2.5g支2.500 g克红霉素片（肠溶）0.125g片0.125 g克1.0g红霉素片（肠溶）0.25g片0.250 g克1.0g红霉素片（肠溶）0.725g片0.725 g克1.0g琥乙红霉素片0.125g片0.125 g克2.0g罗红霉素胶囊0.15g片0.150 g克0.3g罗红霉素片0.05g片0.050 g克0.3g罗红霉素片0.075g片0.075 g克0.3g罗红霉素片0.15g片0.150 g克0.3g克拉霉素胶囊0.25g片0.250 g克0.5g克拉霉素颗粒剂0.0375g包0.037 g克0.5g克拉霉素注射剂0.3g支0.300 g克1.0g克拉霉素注射剂0.6g支0.600 g克1.0g克拉霉素片0.05g片0.050 g克0.5g克拉霉素片0.125g片0.125 g克0.5g克拉霉素片0.25g片0.250 g克0.5g克拉霉素片0.5g片0.500 g克0.5g阿奇霉素胶囊0.25g片0.250 g克0.3g阿奇霉素颗粒剂0.1g包0.100 g克0.3g阿奇霉素颗粒剂0.25g包0.250 g克0.3g阿奇霉素注射剂0.125g支0.125 g克0.5g阿奇霉素注射剂0.1g支0.100 g克0.5g阿奇霉素注射剂0.25g支0.250 g克0.5g阿奇霉素注射剂0.2g支0.200 g克0.5g阿奇霉素注射剂0.5g支0.500 g克0.5g阿奇霉素干混悬剂0.1g包0.100 g克0.3g阿奇霉素片0.25g片0.250 g克0.3g吉他霉素注射剂0.2g支0.200 g克1.0g吉他霉素片0.1g片0.100 g克1.0g吉他霉素片0.1g片0.100 g克1.0g吉他霉素片0.2g片0.200 g克1.0g麦迪霉素胶囊0.1g片0.100 g克1.0g麦迪霉素片0.1g片0.100 g克1.0g交沙霉素胶囊0.2g片0.200 g克2.0g交沙霉素片0.2g片0.200 g克2.0g罗他霉素片0.1g片0.100 g克0.8g乙酰螺旋霉素片0.1g片0.100 g克3.0g依托红霉素混悬剂0.125g包0.125 g克1.5g依托红霉素注射剂0.2g支0.200 g克1.5g依托红霉素片0.125g片0.125 g克1.5g泰利霉素片0.4g片0.400 g克0.8g泰利霉素片0.8g片0.800 g克0.8g地红霉素片0.25g片0.250 g克0.5g乙酰麦迪霉素片0.1g片0.100 g克1.0g麦白霉素片0.1g片0.100 g克1.0g竹桃霉素注射剂0.2g支0.200 g克1.0g金霉素眼膏2.5g支2.500 g克环酯红霉素片0.125g片0.125 g克0.75g环酯红霉素片0.25g片0.250 g克0.75g万古霉素注射剂（稳可信）0.5g支0.500 g克2.0g去甲万古霉素注射剂0.4g支0.400 g克1.2g多粘菌素B注射剂50mg支50.000 mg克0.15g粘菌素（多粘菌素E）注射剂0.15g支0.150 Mu克3.0MU替考拉宁注射剂0.2g支0.200 g克0.4g替考拉宁注射剂0.4g支0.400 g克0.4g舒巴坦钠注射剂0.25g支0.250 g克1.0g舒巴坦钠注射剂0.5g支0.500 g克1.0g林可霉素滴眼剂0.2g:8ml支0.200 g克林可霉素注射剂0.6g支0.600 g克1.8g林可霉素片0.25g片0.250 g克1.8g克林霉素胶囊0.075mg粒0.075 g克1.2g克林霉素胶囊0.15g片0.150 g克1.2g克林霉素凝胶10.0g支10.000 g克克林霉素注射剂0.3g支0.300 g克1.8g克林霉素注射剂0.6g支0.600 g克1.8g克林霉素注射剂0.9g支0.900 g克1.8g克林霉素片0.075g片0.075 g克1.2g甲硝唑注射剂0.5g支0.500 g克1.5g甲硝唑注射剂0.915g支0.915 g克1.5g甲硝唑氯已定洗剂100ml瓶100.000 ml克甲硝唑片0.2g片0.200 g克2.0g甲硝唑阴道泡腾片0.2g片0.200 g克0.5g替硝唑胶囊0.25g粒0.250 g克2.0g替硝唑胶囊0.5g粒0.500 g克2.0g替硝唑注射剂0.4g瓶0.400 g克1.5g替硝唑注射剂0.8g瓶0.800 g克1.5g替硝唑片0.5g片0.500 g克2.0g替硝唑阴道泡腾片0.2g片0.200 g克奥硝唑注射剂0.25g瓶0.250 g克1.0g奥硝唑注射剂0.5g瓶0.500 g克1.0g奥硝唑片0.25g片0.250 g克1.5g奥硝唑片0.5g片0.500 g克1.5g塞克硝唑片0.25g片0.250 g克2.0g磷霉素注射剂2.0g支2.000 g克8.0g磷霉素注射剂3.0g支3.000 g克8.0g磷霉素注射剂4.0g支4.000 g克8.0g磷霉素钙甲氧苄啶胶囊0.15g粒0.150 g克1.5g夫西地酸注射剂0.125g支0.125 g克1.5g夫西地酸注射剂0.5g支0.500 g克1.5g夫西地酸乳膏10g支10.000 g克利福霉素钠注射剂0.25g支0.250 g克0.6g利奈唑胺注射剂0.2g:100ml支0.200 g克1.2g利奈唑胺注射剂0.4g:200ml支0.400 g克1.2g利奈唑胺注射剂0.6g:300ml支0.600 g克1.2g利奈唑胺片0.4g片0.400 g克1.2g利奈唑胺片0.6g片0.600 g克1.2g磺胺嘧啶注射剂0.4g支0.400 g克4.0g磺胺嘧啶注射剂1.0g支1.000 g克4.0g磺胺嘧啶片0.5g片0.500 g克0.6g磺胺甲噁唑片0.5g片0.500 g克2.0g柳氮磺胺吡啶片0.25g片0.2