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roxithromycin dispersible capsulesluohongmeisu jiaonang9o2c41h76n2o15837.03 14p50st-rnapap (cmax)150 mg2cmax)6.67.9 mg/l2.5 mg/l9657.4(t1/2?)8.415.5 512 150mg2300mg1 2.55mg/kg2alt ast1(t1/2?)2 150mg12 150mg13413450.05 12 0.15g(15iu) roxithromycin capsulesluohongmeisu jiaonang9-0-2- c41h76n2o15 837.0314p50st-rnapap(cmax)150mg2cmax6.67.9mg/l2.5mg/l96%57.4%(t1/2)8.415.55121150mg22300mg12.55mg/kg2altast1(t1/2)21150mg1 21150mg1 3 4134 50.05%1 2150mg(15)6/02- ? roxithromycinluo hong mei su pian c41h76n2o15 837.07 a/ /mrsamrseg 50s dinncclsmic (din 58940)Q1 mg/l2-4 mg/l8 mg/l nccls 4400mg/kg/25 60152150mg 6.6mg/l121.8mg/l 12150mg241224 9.3mg/l3.6mg/l1224300mg1110.9mg/l241.7mg/l 300mg1.517.8mg/l300mg2.210.2mg/l243.4mg/l 0.4 l/kg -1-0.84-4.2 mg/l96.493.38.4mg/l86.612.6mg/l73.4 35 8-122016543010totalextrarenalcltot 3.630.49 ml/min clextrarenal 3.240.59 ml/min10-20 198512 1535-10300mg,150mg150mg40kg300mg2007021420070427roxithromycin tabletsluohongmeisu pian9o(2)c41h76n2o15837.03 0.15g5121(150mg)22300mg12.55mgkg2(altast)1(t1/2)2112(11)34(134)50.051015-1-1058mg/kg/40231.6%3500/mm34%1500/mm31. 2%1000/mm31214p50st-rnapap(cmax)150 mg2(cmax)6.67.9 mg/l2.5 mg/l9657.4(t1/2)8.415.56/1/242005h20057254222151280512-656268680512-656286882006713roxithromycin capsulesluohongmeisu jiaonang9o2c41h76n2o15837.030.15g15512 150mg2300mg1 2.55mg/kg2alt ast1(t1/2?)2150mg12150mg13413450.051214p50st