简介Waters UPLC故障排除

WatersUPLCTroubleshootingTraining Agenda ACQUITYUPLCFamily UPLC H ClassWatersUPLCSystemUPLCSolventManagement BSM UPLCSampleManagement SM WatersACQUITYH ClassSystemQuaternarySolventManager QSM SampleManager FlowThroughNeedle SM FTN WatersUPLCDetectorTroubleshootingTrainingWatersUPLCPDAandPDAe TUVFLRELSDOpenDiscussion ACQUITYUPLCFamily ACQUITYUPLCSystem ACQUITYUPLCSystem Detectors Opticaland orMassSpecTunableUVorPhotodiodeArrayOptimizedflowcellforUPLCHighspeeddatasampling ColumnManager InnovativepivotdesignPositionscolumntodetectorE Cordconnection SampleManager LowdispersionXYZZ FormatFastcycletimesLowcarryoverPlatesand orvialsOptionalSampleOrganizer BinarySolventManager HighpressureblendingBinarygradientsFoursolventchoicesOn linedegassingLowdispersiondesignUPLCpressurecapabilities SampleOrganizer option Expandscapacity 22 15 8 ShuttlesplatefeedHeated chilled SystemConsiderations SmallFootprintRedesignedtubingandfittingsConsolidatedwastemanagementIntegratedsystemdiagnosticsConnectionsInsightremotediagnostics FluidicsandConnections TubingmanagementChromatographicsolvents A1 A2 B1 B2TwoSampleManagerwashsolventsSealWashCommonfittingsandtoolsforusersColumninlets outletsandfittingsFingertight turn use1 4 wrench Dedicatedtubing3piececompressionscrewandferruleSmallfootprint 13 wide24 25 withSampleOrganizer UPLCSolventManager ACQUITYUPLCSystemSolventDelivery 15KpsiperformanceAccurateandpreciseflowratesAccurateandprecisecompositionLowdelayvolumeforgradientapplications 120 LSystemVolumeLongtermreliability BinarySolventManagerComponents Filter Mixer TeeAssembly A PumpAccumulator A PumpSolventSelectValve B PumpSolventSelectValve A PumpPrimary B PumpPrimary B PumpAccumulator SixChannelDegasser IntelligentIntakeCheckValves ACQUITYUPLCSystemFromSerialtoParallelFlow TwoindependentlydrivenprimaryandaccumulatorpistondrivesSeparatedrivemotorsTwotransducersTwoinletcheckvalvesFourSolventsCapabilityA1orA2andB1orB2TwosolventspergradientSixChannelDegasser4chromatographiceluents2solventsforSampleManagerStrong weakwash BinarySolventManagerInteractiveDisplay RecommendedSolventsList ACQUITYUPLCSystemrecommendedSolventsMethanolMethanol watermixturesWaterAcetonitrile watermixturesAcetonitrile ACN Isopropanol IPA Samplediluents inadditiontothesolventslistedabove Dimethylsulfoxide DMSO Dimethylformamide DMF Additives Modifiers0 2 formicacid0 1 trifluoroaceticacid TFA 0 1 triethylamine TEA 0 1 hexafluorobutericacid10mMphosphatebuffer10mMammoniumbicarbonate50mMammoniumhydroxide50mMammoniumacetate0 1 Ethylenediaminetetraaceticacid EDTA CleanersPhosphoricacid 30 Sodiumhydroxide 1M ACQUITYUPLCSystemnon recommendedSolventsMethylene ChlorideChloroformStrongacids 5 EthylAcetateTolueneChlorinatedsolvents Trichlorobenzene UPLCSampleManager SampleManagerFluidicsTray PressureTransducerValveManifold DriveGears WashSyringesWeakWashStrongWash MeteringSyringeDriveAssembly MeteringSyringeValve3WayRotaryValve MeteringSyringeAssembly SampleSyringe50uLvolumePN410001348100 LvolumePN700002570250 LvolumePN410001347forusewith50 Lloop ColumnHeatingCompartment ACQUITYIn LineFilter 19 ColumnIn LineFilterAssembly ColumnIn LineFilterAssembly ColumnHeating SampleManagerFlowPath AvailableLoops DescriptionP NStatus1 LLoop430001516Optional2 LLoop430001264Optional5 LLoop430001233Optional10 LLoop430001326Standard20 LLoop430001320Optional50 LLoop430001325Optional100 LLoop170001792 Kit Optional250 LLoop176001780 Kit Optional VolumeConfigurationMenu BeforerunningtheCharacterizeNeedleandLoopVolumefunction makesurethepropervolumesareconfiguredintheVolumesConfigurationmenu TheabovevaluesarestandardforcurrentlyshippingACQUITYsystem RecommendedInjectionVolumes LoopSizesandInjectionModes RecommendedPLNOinjectionvolume20 to75 ofloopvolumeRecommendedPartialLoopInjection20 to50 ofloopvolume ACQUITYH ClassSystem QSMQuaternarySolventManager SM FTNSampleManager FlowThroughNeedle CH AHighTemperatureColumnHeaterActivePre Heating DetectorsTUV PDAe PDA FLR ELSD TheACQUITYH ClassSystemconsistsofthefollowing QuaternarySolventManager QSM FoursolventlowpressuregradientmixingSupportsUPLCPressuresLowgradientdelayvolumeSM FTN SampleManager FlowThroughNeedle Oneinjectionmode directinjecttypeMuchsimpler JustspecifyinjectionvolumeExcellentrecoveryandprecisionCH AHightemperaturecolumnheaterwithactivepre heating ACQUITYH ClassSystem QSMFluidics FrontView PrimaryHead AccumulatorHead VentValve 100ulMixer GradientProportioningValvePairs LowPressureManifold DegasserChambers SealWashPump QSMConsoleTopLevelMenu ACQUITYH ClassSystem SMDIFrontPanelFluidics MeteringSyringeValve CheckValveandUnion InjectValve WashSolventInletLine notdegassed LeakSensorConnections SampleMeteringSyringe SDMIInjectValveConnections ToCheckValve ToCH AandColumn StationarySideTube FromPump ToPressureTransducer ToSampleNeedle SampleCompartment PowerandStatusLEDs PlateSelectorSwitch RotaryTray PlateHolder MagneticDoorSensor PowerSwitch SM FTNInteractiveDisplayMenu CH A ImprovedDoorGasket AddedTubingGasket topandbottom For3rdpartyMassSpecatleftsideofACQUITYStack AllowsuseofexistingPassivePre heater NowirestoconnectActivePre heater InstallingtheActivePre Heater GoldPlatedCompressionScrew PEEKFerrule StainlessSteelCapNut StainlessSteelTubing withbrazedoncollet InstallingtheActivePre Heater UPLCDetectors Detectors SupportsallcurrentACQUITYdetectorsPDA