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依据时辰药理学指导临床合理用药李丽华赵喜荣（解放军264医院药剂科山西太原030001）A1A0A0A3A3A4A2A5A6A7A8A9A10A11A12A13A14A15A16A17A18A19A20A21A22A23A24A25A26A27A18A28A17A29A30A31A32A33A34A35A35A36A36A31A32A37A21A38A39A40A41A42A23A43A27A25A26A28A17A44A45A46A47A23A48A49A50A51A52A43A33A53A54A53A54A53A54A36A36A36A55A56A57A9A58A17A11A20A59A60A12A13A23A61A62A25A26A63A64A20A65A17A15A66A33A53A67A53A67A53A67A36A36A25A26A68A17A60A69A70A57A9A58A17A11A20A59A60A20A12A13A40A71A28A15A16A72A73A63A64A20A68A17A15A66A40A68A17A74A75A23A76A77A29A78A17A11A20A79A80A81A82A23A83A84A28A17A85A86A23A83A87A17A11A88A89A59A60A33A90A21A91A92A93A27A18A28A17A94A28A17A15A66A94A15A16A17A18A90A95A96A97A50A98A99A93A100954A90A38A39A101A102A103A93A104A15A16A17A18A105A106A107A57A9A58A17A11A20A59A60A14A15A66A37A21A108,A109A110A17A18A81A60A14A111A108A112A17A11A113A114A115A116A19A40A10A11A117A28A118A119A120A15A66A121A10A122A123A20A124A13A33A25A26A68A17A74A75A20A125A126A127A128A105A129A56A17A113A115A116A19A31A130A40A131A9A68A17A74A132,A133A84A32A134A8A9A135A88A136A15A66A58A17A11A71A28A88A136A137A127A15A16A17A18A19A138A139A33A135A25A26A68A17A15,A55A56A15A16A17A18A19A138A108A40A57A9A20A10A11A12A13A122A123A72A73A63A64A20A68A17A15A66A23A61A62A27A18A79A80A28A17A74A75,A29A78A17A11A20A80A81,A83A84A28A17A85A86A40A111A140A59A60A331A57A9A20A10A11A12A13A14A15A16A17A18A19A46A141A106A107A142A143A8A9A20A10A18A144A145A131A146A7724A147A15A24A148A149A20A12A13A108A122A123A23A135A10A11A150A20A151A152A40A153A12A154A57A9A20A155A156A113A114A112A9A157A122A123A112A158A159A160A86A40A161A162A50A163A119A144A145A164A131A146A127A62A20A122A123A12A13A23A135A138A62A15A66A131A146A78A165A166A33A57A9A20A167A168A12A13A169A122A170A17A11A20A17A115A19A40A17A81A19A23A171A172A173A174A170A17A11A20A10A11A117A28A118A40A58A175A176A20A79A80A33A177A178A179A180A181A182A10A183A184A185A14A186A187A181A182A131A146A88A136A20A10A11A12A13A23A179A180A181A182A135A188A18910A15A10A183A63A190A191A23A172A186A187A181A182A135A154A1894A15A10A183A63A192A23A193A77A23A188A18910A15A194A28A195A179A180A17A11A196A197A198A15A66A194A28A199A64A332A15A16A17A18A19A14A27A18A28A17A25A26A188A23A136A200A175A176A88A136A20A201A9A194A28A136A127A200A112A37A136A85A86A20A17A11A79A80A15A23A202A203A10A88A136A20A79A80A81A60A23A136A127A201A9A17A11A40A85A86A37A136A135A88A136A15A66A68A17A23A204A76A203A10A88A136A20A79A80A81A60A23A186A61A205A68A17A15A66A14A28A17A85A86A135A25A26A188A105A136A119A206A207A20A23A208A209A23A25A26A28A17A23A127A62A207A32A134A8A9A20A10A11A12A13A23A72A73A63A64A20A68A17A15A66A332A2101A159A211A212A161A162A178A8A9A161A162A50A163A146A143A213A20A167A168A12A13,A214A2157A2168A15A105A8A9A161A162A50A163A20A78A217A33A46A218A219A25A26A28A17A220A221A222A197A223A126A43A82A121A224,A225A226A2147A2168A15A68A159A211A212A161A162A127A227,A197A80A81A143A213A228A229A225A226A50A227A68A17,A230A58A183A149A28A17A231A232A233A234A17A204A133A84A121A10A234A17A235A236A23A237A238A239A183A149A60A28A159A211A212A161A162A20A176A8,A240A28A214A2151A227A68A17A241A242A226A214A2151A227A68A17,A88A243A76A244A245A63A64A80A81A23A204A76A83A84A194A17A11A20A88A89A59A60A40A234A17A246A20A111A140A59A601A33A247A183A149A60A28A183A81A159A211A212A161A162A177A205A248A249A250A112A251A252A249A250A119A231,A204A76A240A28A242A226A80A97,A253A254A255A241A20A52A86A229A127A226A2147A2168A15A11A65,A197A228A185A108A0A50A143A213A33A135A159A211A212A161A162A50A163A165A217A149A168A6612A15A1A2,A68A56A3A85A86A159A211A212A161A162,A76A254A79A80A252A253A4A5A6A7A8A175A9A10A16A12A13A14A151A239,A125A17A18A19A20A21A22A23A52A24A292A1982A22A147A25A26A27A28A25A30A165A31A16A147A25A101A30A25A148A32A33A34A16A35A36A37A38,A25A30A165A31A39A40A2034A17A41A42A43A151A44A45A46A52A47A48A49A50A22A147A25A51A53A52A54,A197A17A55A57A58A24A154A59A60A61A62A63A64A65A13A69A50A231A66A67A217A17A68A70A71A50A40A2034A17A44A45A42A43A151A72A73A74A32A31A75A76A29A31A77A39A78A79A2341HA248A80A77A81A147A25A82A107A61A83A15A84,3HA234A147A25A82A107A85A86A87A217A88A175A29A196A197A50A33A116A89A47A90A9115A20430A92A93A44A45A42A43A151A13A69A58A94A50A231A95A21A96A97A98A99A100A102A32A181A103A104A105A106A108A22A147A25A26A175A109A110A91A229A110A234A111A136A17A108A53A105A166A112A219A90A91A147A25A15,A113A114A53A26A115A53A90A17A68A68A117A21A118A41A119A171A50A120A90A91A147A25A24A18A121A217A24A147A25A50A44A45A234A122A21A123A180A53A90A29A161A124A126A90A91A175A109A44A45A24A127A128A42A43A151A161A129A25A30A165A112A219A50A52A94A130A131A23A132A91A53A26A50A133A134A61A135A137A36A68A24A147A25A115A157A203A27A28A15A147A25A138A1392,3A29A98A140A141A98A50A157A90A91A108A53A136A154A59A142A143A144A14525A146A149A184A157A90A150A10875A146A149A12A13A14A15804A29A187A32A152A219A50A166A142A143A153A145A124A39A157A90A91A229A155A33A156A158A90A17A108A53A50A159A160A162A25A16A163A164A187A47A167A142A50A21A168A1551A2042A106A110A169A108A50A170A16A66A172A173A174A176A177A178A179,A182A183A186A188A189A6A29A161A190A142A143A191A192A193A4A26A194A18A125A50A78A90A192A26A194A195A199A115A200A201A202A205A206A118A70A6A50A61A39A90A23405A20410A136A17A207A81A108A53A50A133A158A66A208A55A26A17A68A192A26A194A209A210A16A211A212A213A6A115A2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