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1、抗生素医学-1: For severe bacterial infections, antibiotics are usually first given by injection. When the infection is under control, antibiotics can then be taken by mouth. Less severe infections can be treated from the start with oral antibiotics. Antibiotics need to be taken until the infecting organi
2、sm is eliminated from the body, which may be days after the symptoms disappear. Antibiotics are rarely given for fewer than 5 days (an exception is certain uncomplicated urinary tract infections). Discontinuing treatment too soon can result in a relapse of infection or the development of antibiotic-
3、resistant bacteria.A doctor, nurse, or pharmacist can explain how the prescribed antibiotic should be taken. Some antibiotics must be taken on an empty stomach, whereas others may be taken with food. Metronidazole, a common antibiotic, causes an unpleasant reaction with alcohol. Also, some antibioti
4、cs can interact with other drugs a person may be taking, possibly reducing the effectiveness or increasing the side effects of the antibiotic or the other drugs. Some antibiotics make the skin sensitive to sunlight.In addition to treating existing infections, antibiotics are sometimes used to preven
5、t infections (prophylaxis). Antibiotics may be used to prevent meningitis in people who have been exposed to someone with meningitis. Some people with abnormal or artificial heart valves take antibiotics before dental and surgical procedures to prevent bacteria from infecting the damaged valves. Pro
6、phylactic antibiotics may also be given to people who have a weakened immune system, such as people with leukemia, people receiving chemotherapy for cancer, or people with AIDS. People undergoing surgery that has a high risk of introducing infection (such as major orthopedic or intestinal surgery) m
7、ay also be given antibiotics. To be effective, and to avoid the development of resistance in bacteria, prophylactic antibiotic therapy is used for only a short time.Your translation: 对于严重细菌感染,抗生素通常首选注射给药,感染得到控制时方可口服给药。对于不太严重的感染,起始就可口服抗生素。待侵袭菌从机体清除,症状消失方可停用抗生素,这可能要数天时间。抗生素给药极少少于五天(除非针对的是某些单纯尿道感染),停药太
8、早可能导致感染复发或抗生素耐药菌的产生。医生,护士或者药剂师会解释所开的抗生素该如何服用。有些抗生素须空腹服,而另外一些可与进食同服。例如甲硝唑是一种常用抗生素,饮酒后会导致不适反应;另外,一些抗生素可与你正在服用的其他药物相互作用,可能降低抗生素本身或者其他药物的药效,抑或增加药物的副作用;而一些抗生素导致皮肤对光敏感。抗生素除了用于治疗既存感染外,还可用于预防感染(预防用药)。例如抗生素可用于接触感染性脑膜炎;异常或人工心瓣膜患者在牙科诊治和外科手术前服用抗生素以防细菌侵袭受损瓣膜;抗生素预防用药也可用于免疫系统低下患者,如白血病病人,接受化疗的癌症病人及艾滋病人;病人进行有高风险感染的外
9、科手术例如大型整形外科手术、肠道手术也要预防性给予抗生素。抗生素预防用药只能短期应用,以达到药物疗效及避免细菌耐药性产生。公司点评(测试人不必填写) (词汇)术语错误: 拼写错误: 标点符号: (句子)语法错误: 漏译: 错译: (文章)总字数: 抗生素医学-2:抗菌药物具有以下特点:(1)抗菌药物直接作用于病原菌,并能杀灭或抑制这些病原菌;(2)根据体外药物敏感性试验结果以及对药物的作用机制、药代动力学特性和药效学的了解,可以预测此药物对许多细菌感染的疗效;(3)可以通过生物分析或化学方法测定在体液和组织中的具有一定活性的药物浓度;(4)抗菌药物可以影响正常菌群,可以改变肠道、其他粘膜表面和
10、皮肤上寄生或定植的微生物的竞争(生态学的)、营养和代谢功能。这些变化可以导致原先感染部位或远处出现新的微生物所致的二重感染;(5)微生物可以通过突变、转导、遗传物质转移或基因诱导而对抗菌药物产生耐药。(6)接受抗菌药物治疗者体内所诱导出的耐药菌可以向未感染的人群传播;(7)具有N-甲基硫四氮唑的化合物可干扰凝血素的合成;某些广谱青霉素和头孢菌素可以影响血小板聚集;少数情况下,改变肠道微生物种群的抗菌可以增强抗凝药物的活性。Your translation: Antibacterial drugs have following characteristics:1)They act directl
11、y upon bacteria, killing or inhibiting these microbes; 2)Their therapeutic effects of bacterial infections can be predicted according to the results of in vitro drug-sensitive tests, and knowledge of the mechanism of drug actions, features of pharmacokinetics and pharmacodynamics; 3)The concentratio
12、n of active drugs in body fluids and tissues can be tested through biological analysis or chemical means; 4)They can affect normal flora and alter the ecological competition, nutrition and metabolic functions of bacteria which parasitize in or inhabit the intestinal tracts, other mucosa surface and
13、the skin, which may cause superinfection at the previously infected place or the distance; 5)Bacteria can develop resistance to antibacterial drugs by mutation, transduction, transformation of hereditary substance or genetic induction; 6)The drug-resistant bacteria derived from the patient who has received antibacterial therapy can be transmitted to the uninfected; 7)Chemicals with N-methlthiotetrazole can interfere the synthesis of prothrombin; Certain broad-spectrum penicillins and cephalosporins may affect the cong
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