Trelagliptin-succinate-SYR-472-succinate-DataSheet-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemETrelagliptin succinateCat. No.: HY-15408ACAS No.: 1029877-94-8Synonyms: SYR-472 succinate分式: CHFNO分量: 475.47作靶点: Dipeptidyl Peptidase作通路: Metabolic Enzyme/Protease储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1

2、month溶解性数据体外实验 DMSO : 50 mg/mL (105.16 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.1032 mL 10.5159 mL 21.0318 mL5 mM 0.4206 mL 2.1032 mL 4.2064 mL10 mM 0.2103 mL 1.0516 mL 2.1032 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验请根据您的实验动物和给药式选择适当的溶

3、解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.5 mg/mL (5.26 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.5 mg/mL (5.26 mM); Clear solut

4、ion1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.5 mg/mL (5.26 mM); Clear solutionBIOLOGICAL ACTIVITY物活性 Trelagliptin succinate (SYR-472 succinate)是长效的DPP-4抑制剂。REFERENCES1. Efficacy of SYR-472 in Subjects With Type 2 Diabetes Mellitus2. Efficacy and Safety of SYR-472 in Subjects With Type 2 Diabetes Mellitus3. Long-term Study of SYR-4724. SYR-472 Open-label StudyMcePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>