Sunifiram-DM-235-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemESunifiramCat. No.: HY-17550CAS No.: 314728-85-3Synonyms: DM-235分式: CHNO分量: 246.3作靶点: iGluR作通路: Membrane Transporter/Ion Channel; Neuronal Signaling储存式: 4C, stored under nitrogen* In solvent : -80C, 6 months; -20C, 1 month (store

2、d undernitrogen)溶解性数据体外实验 H2O : 50 mg/mL (203.00 mM; Need ultrasonic)DMSO : 2.6 mg/mL (10.56 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 4.0601 mL 20.3004 mL 40.6009 mL5 mM 0.8120 mL 4.0601 mL 8.1202 mL10 mM 0.4060 mL 2.0300 mL 4.0601 mL请根据产品在不同溶剂中的溶

3、解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Sunifiram (DM-235)是ampakine样化合物，具有较piracetam更好的益智活性。REFERENCES1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE1. Galeotti N, et al. AMPA-receptor activation is involved in the antiamnesic effect of DM 232 (unifiram) and DM 235 (sunifiram). Nauny

4、nSchmiedebergs Arch Pharmacol. 2003 Dec;368(6):538-45.2. Moriguchi S, et al. Novel nootropic drug sunifiram enhances hippocampal synaptic efficacy via glycine-binding site of N-methyl-D-aspartate receptor. Hippocampus. 2013 Jun 3.3. Moriguchi S, et al. Novel nootropic drug sunifiram improves cognitive deficits via CaM kinase II and protein kinase C activation inolfactory bulbectomized mice. Behav Brain Res. 2013 Apr 1;242:150-7.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;/p>