Metoclopramide - Dopamine Receptor Antagonist - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEMetoclopramideCat. No.: HY-17382CAS No.: 364-62-5分式: CHClNO分量: 299.8作靶点: Dopamine Receptor作通路: GPCR/G Protein; Neuronal Signaling储存式: 4C, protect from light* In solvent : -80C, 6 months; -20C, 1 month (protect fromlight)溶解性数据体外实

2、验 DMSO : 41 mg/mL (136.76 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 3.3356 mL 16.6778 mL 33.3556 mL5 mM 0.6671 mL 3.3356 mL 6.6711 mL10 mM 0.3336 mL 1.6678 mL 3.3356 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Metoclopramid

3、e多巴胺D2受体拮抗剂，可吐。REFERENCES1. Navari RM, Nagy CK, Gray SE. The use of olanzapine versus metoclopramide for the treatment of breakthrough chemotherapy-inducednausea and vomiting in patients receiving highly emetogenic chemotherapy. Support Care Cancer. 2013 Jan 12.2. Gutirrez-Hermosillo H, Daz de Len-G

4、onzlez E, Beltrn Santiago D et al. Metoclopramide as a risk factor for postprandial1/2 Master of Small Molecules 您边的抑制剂师www.MedChemEhyperglycemia in type 2 diabetes. Nutr Hosp. 2012 Jul-Aug;27(4):1267-71.3. Ilan Matok, Sc.Pharm., Rafael Gorodischer, et al. The Safety of Metoclopramide Use in the Fir

5、st Trimester of Pregnancy. N Engl J Med2009; 360:2528-2535.4. DN Bateman, C Kahn, K Mashiter, DS Davies. Pharmacokinetic and concentration-effect studies with intravenous metoclopramide.British Journal of Clinical Pharmacology.1978,6(5): 401-407McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58