细胞和组织损伤与修复课件

实验二细胞组织的损伤和修复（二）1实验二1目的要求：掌握坏死的类型、形态学变化，认识其可能产生的后果。掌握肉芽组织的形态特点与功能。2目的要求：掌握坏死的类型、形态学变化，认识其可能产生的后果。实验内容1.Multimedia(25min)2.samples(40min)coagulativenecrosisofspleencoagulativenecrosisofkidneycaseousnecrosisofkidneygangreneoffootamoebicabscessofliver(liquefactivenecrosis)3实验内容1.Multimedia(25min)33.Sections(80min)16#coagulativenecrosisofspleen

35#caseousnecrosis38#pathologicalcalcification22#granulationtissue

(drawing)4.CPC(30min)5.Summary(5min)实验内容43.Sections(80min)实验内容416#16#

coagulativenecrosisofspleen

516#16#coagulativenecrosis5normalspleen6normalspleen6normalnucleuspyknosiskaryorrhexiskaryolysis7716#coagulativenecrosisofspleen816#coagulativenecrosis835#caseousnecrosis935#caseousnecrosis935#caseousnecrosis1035#caseousnecrosis1035#caseousnecrosis1135#caseousnecrosis1135#caseousnecrosis1235#caseousnecrosis1235#caseousnecrosis1335#caseousnecrosis1335#caseousnecrosis1435#caseousnecrosis1422#22#granulationtissue1522#22#granulationtissue1522#granulationtissue1622#granulationtissue1638#pathologicalcalcification1738#pathological17SpleenCoagulativeNecrosiscoagulativenecrosisofspleenandkidney

18SpleenCoagulativeNecrosiscoaamoebicabscessofliver19amoebicabscessofliver19caseousnecrosisofkidney20caseousnecrosisofkidney2caseousnecrosisofkidney21caseousnecrosisofkidney2caseousnecrosisoflung22caseousnecrosisoflung22drygangrene23drygangrene23wetgangrene24wetgangrene24gasgangrene25gasgangrene25病例讨论病史摘要：李××，男，38岁，与本村张××打架时，被张用锐器刺伤左小腿后侧腓肠肌处，该处形成开放性损伤，事后小腿肿胀、疼痛难忍，第二天出现红、肿、热、痛，第三天体温达39.5C；第四天下肢高度肿胀，下达足背，皮肤裂口处流出血水。在乡医院用大量抗菌素治疗，未见疗效；第六天，左足拇指呈黑色；第十天黑色达足背，与正常组织分界不清。后到县医院治疗，行左下肢截肢术。26病例讨论病史摘要：26病理检查：下肢高度肿胀，足部污黑色，纵行剖开动、静脉后见动、静脉血管腔内均有暗红色与灰白色相间的固体物阻塞，长约10cm，与管壁粘着。固体物镜检为混合血栓。讨论题：病人所患何病？其发生机制是什么？27病理检查：27诊断（1）左小腿开放性损伤（2）左小腿动、静脉血栓（3）足湿性坏疽发生机制：左小腿外伤→局部感染→动脉炎→静脉炎→继发血栓形成→动脉缺血，静脉回流障碍→足坏死、感染、变黑（坏疽）。28诊断（1）左小腿开放性损伤28THANKYOU!29THANKYOU!29实验二细胞组织的损伤和修复（二）30实验二1目的要求：掌握坏死的类型、形态学变化，认识其可能产生的后果。掌握肉芽组织的形态特点与功能。31目的要求：掌握坏死的类型、形态学变化，认识其可能产生的后果。实验内容1.Multimedia(25min)2.samples(40min)coagulativenecrosisofspleencoagulativenecrosisofkidneycaseousnecrosisofkidneygangreneoffootamoebicabscessofliver(liquefactivenecrosis)32实验内容1.Multimedia(25min)33.Sections(80min)16#coagulativenecrosisofspleen

35#caseousnecrosis38#pathologicalcalcification22#granulationtissue

(drawing)4.CPC(30min)5.Summary(5min)实验内容333.Sections(80min)实验内容416#16#

coagulativenecrosisofspleen

3416#16#coagulativenecrosis5normalspleen35normalspleen6normalnucleuspyknosiskaryorrhexiskaryolysis36716#coagulativenecrosisofspleen3716#coagulativenecrosis835#caseousnecrosis3835#caseousnecrosis935#caseousnecrosis3935#caseousnecrosis1035#caseousnecrosis4035#caseousnecrosis1135#caseousnecrosis4135#caseousnecrosis1235#caseousnecrosis4235#caseousnecrosis1335#caseousnecrosis4335#caseousnecrosis1422#22#granulationtissue4422#22#granulationtissue1522#granulationtissue4522#granulationtissue1638#pathologicalcalcification4638#pathological17SpleenCoagulativeNecrosiscoagulativenecrosisofspleenandkidney

47SpleenCoagulativeNecrosiscoaamoebicabscessofliver48amoebicabscessofliver19caseousnecrosisofkidney49caseousnecrosisofkidney2caseousnecrosisofkidney50caseousnecrosisofkidney2caseousnecrosisoflung51caseousnecrosisoflung22drygangrene52drygangrene23wetgangrene53wetgangrene24gasgangrene54gasgangrene25病例讨论病史摘要：李××，男，38岁，与本村张××打架时，被张用锐器刺伤左小腿后侧腓肠肌处，该处形成开放性损伤，事后小腿肿胀、疼痛难忍，第二天出现红、肿、热、痛，第三天体温达39.5C；第四天下肢高度肿胀，下达足背，皮肤裂口处流出血水。在乡医院用大量抗菌素治疗，未见疗效；第六天，左足拇指呈黑色；第十天黑色达足背，与正常组织分界不清。后到县医院治疗，行左下肢截肢术。55病例讨论病史摘要：26病理检查：下肢高度肿胀，足部污黑色，纵行剖开动、静脉后见动、静脉血管腔内均有暗红色与灰白