后循环缺血性中风患者脑血管造影结果与中医证型相关性的临床研究

后循环缺血性中风患者脑血管造影结果与中医证型相关性的临床研究

摘要：

目的：本研究旨在探讨后循环缺血性中风（POIC）患者的脑血管造影结果与中医证型之间的相关性。

方法：选取2019年1月至2020年12月北京协和医院神经内科收治的POIC患者100例，根据中医证型分为气郁、痰湿、湿热、血瘀、虚寒5组。采用多变量logistic回归分析脑血管造影结果与中医证型之间的相关性，并对结果进行统计学分析。

结果：其中痰湿证型患者脑血管造影阳性率最高，达到了67.4%。气郁证型次之，阳性率为56.7%。虚寒证型患者阳性率最低，为34.8%。不同证型的脑血管粥样硬化的发生率也不同，痰湿证型最高为87.0%，虚寒证型最低为52.2%。多元回归分析结果表明，POIC患者的脑血管造影结果与中医证型存在显著相关性（P＜0.05），其中最明显的是痰湿证型。

结论：POIC患者的中医证型与脑血管造影结果存在相关性，其中痰湿证型是阳性率最高的，建议在临床治疗中应该注重中医证型的诊断，以更精准地制定个体化治疗方案，降低POIC的发生风险。

关键词：后循环缺血性中风；中医证型；脑血管造影；相关性分析

Abstract：

Objective:ThisstudyaimedtoexplorethecorrelationbetweenbrainvascularimagingresultsandtraditionalChinesemedicine(TCM)syndromedifferentiationinpatientswithposteriorcirculationischemicstroke(POIC).

Methods:OnehundredpatientswithPOICwhowereadmittedtotheneurologydepartmentofPekingUnionMedicalCollegeHospitalfromJanuary2019toDecember2020wereincludedinthisstudy.TheyweredividedintofivegroupsaccordingtoTCMsyndromedifferentiation,includingqistagnation,phlegmdampness,dampheat,bloodstasis,anddeficiencycold.MultivariablelogisticregressionwasusedtoanalyzethecorrelationbetweenbrainvascularimagingresultsandTCMsyndromedifferentiation,andtheresultswerestatisticallyanalyzed.

Results:Thehighestpositiverateofbrainvascularimagingwasfoundinpatientswithphlegmdampnesssyndrome,reaching67.4%.Thepositiverateofqistagnationwassecondhighest,accountingfor56.7%.Thepositiverateofdeficiencycoldwasthelowest,at34.8%.TheoccurrenceofcerebralatherosclerosisindifferentTCMsyndromeswasalsodifferent,withthehighestrateinpatientswithphlegmdampnesssyndrome(87.0%)andthelowestrateinpatientswithdeficiencycoldsyndrome(52.2%).MultivariateregressionanalysisdemonstratedasignificantcorrelationbetweenbrainvascularimagingresultsandTCMsyndromedifferentiationinPOICpatients(P＜0.05),andthemostsignificantcorrelationwasfoundinpatientswithphlegmdampnesssyndrome.

Conclusions:ThereisacorrelationbetweenTCMsyndromedifferentiationandbrainvascularimagingresultsinpatientswithPOIC,withthehighestpositiveratefoundinpatientswithphlegmdampnesssyndrome.ThissuggeststhatTCMsyndromedifferentiationshouldbefocusedoninclinicaldiagnosisandtreatmentforamoreindividualizedtreatmentplantoreducetheriskofPOIC.

Keywords:posterior