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Diabetes糖尿病英文医疗课件2026/8/27
Terminology
2Combiningformprefixandsuffixmeaningterminologymeaningaden/ogland腺adenitisadenomaadenopathy腺炎腺瘤腺病crin/osecrete分泌endocrinologyhypercrinecrinogenic内分泌学内分泌机能亢进的促分泌的hormon/ohormone激素hormonalhormonogenesishormonology激素的,激素性激素生成内分泌学adren/oadrenalglands肾上腺adrenitisadrenolyticadrenopathy肾上腺炎抗肾上腺素的肾上腺病2026/8/27
Terminology
3Combiningformprefixandsuffixmeaningterminologymeaningpancreat/opancreas胰腺pancreaticpancreatinpancreatogram胰腺,胰脏的胰酶胰造影摄片gluc/osugar糖glucagonglucogenesisglucolysis胰高血糖素葡萄糖生成糖酵解glyc/osugar糖glycopeniaglycosuriahyperglycemia低糖,糖过少糖尿高血糖症insulin/oinsulin胰岛素insulinaseinsulomahyperinsulinism胰岛素酶胰岛素瘤高胰岛素血症2026/8/27
Terminology
4Combiningformprefixandsuffixmeaningterminologymeaningendo-within内endodermendoscopeendoplasm内胚层内镜内质thyroid/othyroid甲状腺thyroiditisthyroidectomyhypothyroidism甲状腺炎甲状腺切除术甲状腺功能减退ovari/oovary卵巢ovariotomyovaritisovariopathy卵巢切开术卵巢炎卵巢病-trophicnutrition,growth,nourishment营养(的)neurotrophicthymotrophicadrenotrophic神经营养性的促胸腺的促肾上腺的01BriefIntroduction02Classification03
Themajorfactors04
Pathogenesis
05
ClinicalManifestations06Complications07
Diagnosis08
Antidiastole09TherapycontentsFigure1:Mainsymptomofdiabetes6Diabetesmellitus,orsimply
diabetes,isagroupofmetabolicdiseasesinwhichapersonhashigh
bloodsugar,eitherbecausethepancreas
doesnotproduceenough
insulin,orbecausecellsdonotrespondtotheinsulinthatisproduced.
Thishighbloodsugarproducestheclassicalsymptomsof
polyuria
(frequenturination),
polydipsia
(increasedthirst),and
polyphagia
(increasedhunger).
01BriefIntroduction702Classification2.1
Type1diabetes
Thepancreas
undergoesanautoimmuneattackbythebodyitself,andisrenderedincapableofmakinginsulin.Abnormalantibodieshavebeenfoundinthemajorityofpatientswithtype1diabetes.Antibodiesareproteinsinthebloodthatarepartofthebody‘simmunesystem,thepatientwithtype1diabetesmustrelyoninsulinmedicationforsurvival.02Classification2.2
Type2diabetes
Itpreviouslyreferredtoasnon-insulindependentdiabetesmellitus,oradultonset
diabetesmellitus.patientscanstillproduceinsulin,butdosorelativelyinadequatelyfortheirbody‘sneeds,particularlyinthefaceofinsulinresistanceasdiscussedabove.Inmanycasesthisactuallymeansthepancreasproduceslargerthannormalquantities
ofinsulin.Amajorfeatureoftype2diabetesisalackofsensitivitytoinsulinbythecellsofthebody.02Classification2.3
Othertypeofdiabetesgestationaldiabetes,occurswhenpregnantwomenwithoutapreviousdiagnosisofdiabetesdevelopahighbloodglucoselevel.Itmayprecededevelopmentoftype2DM.Otherformsofdiabetesmellitusincludecongenitaldiabetes,whichisdueto
genetic
defectsofinsulinsecretion,
cysticfibrosis-relateddiabetes,steroiddiabetesinducedbyhighdosesof
glucocorticoids,andseveralformsof
monogenicdiabetes.2026/8/27meta-变化的metabolismn.新陈代谢
metaboliten.代谢物
metabolizev.使新陈代谢
metabolicadj.变化的,新陈代谢的
poly-多的,多个的,聚合的
polydipsia多饮
polyuria多尿
polyphagia多食
WordAnalysis2026/8/27uri-尿的,与尿有关的
urinen.尿polyuria多尿uricadj.尿的
urinaln.尿壶
urinatev.小便
urinationn.排尿
glucosuria糖尿WordAnalysis2026/8/27Birthweight:FatIrregularmenses(menstruation)InflammationObesity
andasedentary
lifestyleSmokingMetabolicsyndrome
03
Themajorfactors03
Themajorfactors
3.1
BirthweightThereisarelationshipbetweenbirthweightanddevelopingdiabetes.Thehigherthebirthweightthehighertheriskoftype2diabetes.Attheotherendofthespectrum,averyhighbirthweight(over8.8poundsor4kg)alsoisassociatedwithanincreasedrisk.Additionally,mothersofinfantswhohadahigherbirthweight(over9pounds)areatincreasedriskfordevelopingdiabetes.03
Themajorfactors
3.2
FatThedistributionoffatisimportant.Theclassic"pear"shapeperson(smallerwaistthanhips)hasalowerriskofdevelopingdiabetesthanthe"apple"shapeperson(largeraroundthewaist).Theexactreasonforthisdifferenceisunknown,butitisthoughttohavesomethingtodowiththemetabolicactivityofthefattissueindifferentareasofthebody.03
Themajorfactors
3.3
Irregularmenses(menstruation)
Thereisanassociationbetweenthelengtheningofthemenstrualcycleandtheriskfordevelopingdiabetes,particularlyinobesewomen.thosewhohadacyclelengthofgreaterthan40daysweretwiceaslikelytodevelopdiabetesthanthosewhocycledevery26to31days.Theassociationisthoughttobelinkedwithpolycystic
ovariansyndrome(PCOS)whichisalsoknowntobeassociatedwithinsulinresistance.Insulinresistancemaybeaprecursorfortype2diabetes.03
Themajorfactors
3.4
inflammationInrecentyearswehavebeguntounderstandtheimportanceofinflammationandheartdisease.Wenowknowthatinflammationmayplayanimportantroleinthedevelopmentofdiabetesaswell.AninflammationmarkerknownasC-reactiveproteinhasbeenshowntobeincreasedinwomenatriskfordevelopingthemetabolicsyndrome,andinbothmenandwomenatriskfordevelopingtype2diabetes.03
Themajorfactors
3.5
ObesityandasedentarylifestyleObesityandasedentarylifestylearethebiggestriskfactorsthatarecontrollable.Thisisinpartduetothefactthatobesityincreasesthebody'sresistancetoinsulin.Studieshaveshownthatreversalofobesitythroughweightreductionimprovesinsulinsensitivityandregulationofbloodsugar.03
Themajorfactors
3.6
smoking
Smokingisharmfulinmanywaysincludingincreasingtheriskofcancerandheartdisease.Italsoincreasestheriskofdevelopingtype2diabetes.2026/8/27men/o与月经有关的menstruationn.月经menstrualadj.月经的dysmenorrhean.menstrualpainamenorrhea/Menopausen.nomenstruationmetr/o子宫
metrorrhagian.uterinebleedingmetrostaxisn.SmalluterinebleedingWordAnalysis2026/8/27metabolic代谢的metabolicsyndrome代谢综合征lipidmetabolism脂代谢glucosemetabolism糖代谢metabolicacidosis代谢性酸中毒basalmetabolicrate基础代谢率precursor:prodromalsymptomsofdiseaseC-reactiveprotein:Itisasharplyrisedprotein,whentissuesinjuryandinfect.WordAnalysis04
Pathogenesis4.1ThePathogenesisofType1Isrelatedtogeneticfactors,environmentalfactorsandautoimmunity1)geneticpredisposition2)startautoimmuneresponse3)immumologicalabnormalities4)progressivelossofisletBcellfunction5)clinicaldiabetes6)isletBcellsdestroyed,diabetesclinicalmanifestations04
Pathogenesis4.2ThePathogenesisofType2Itsoccurrenceanddevelopmentcanbedividedintofourstages1)Geneticsusceptibility2)Hyperinsulinism,and/orinsulinresistance3)Glucotoxicity(糖尿病毒性),lipotoxicity(脂毒性)4)Clinicaldiabetes2026/8/27immune免疫autoimmunity自身免疫immumological免疫学的hyper-高Hyperinsulinism高胰岛素症Hyperglycemia高血糖toxic毒的,中毒的,有毒的Glucotoxicity糖尿病毒性lipotoxicity脂毒性WordAnalysis05
ClinicalManifestations
5.1Type1DiabetesMellitusPolyuriaPolydipsiaPolyphagiaWeightloss05
ClinicalManifestations
5.2Type2DiabetesMellitusNon-specificsymptomsFatigueRecurrentinfectionsProlongedwoundhealingVisual
changes2026/8/27proteolysis蛋白质水解
lipolysis脂类分解
arthrolysis关节松解术-lysis松解术,分解,溶解
prote-蛋白质
lipo-脂肪的
arthro-关节WordAnalysis06
Complications6.1
DiabeticKetoacidosis(DKA)
Itisthemostcommonacutecomplicationofdiabetesmellitus.TheearlymanifestationsofDKAisthatthesymptomsbeingmoreserve,suchaspolydipsia、polyuria、polyphagiaandsoon.TheDKAischaracterizedbydifferentdegreesofdisturbanceconsciousnessintheadvancedstage.06
Complications6.2
Hyperglycemichyperosmolarstatus(HHS)Mainclinicalfeatures:hyperglycemiacrisis(高血糖危象),higherplasmaosmotic
pressure(高血浆渗透压),dehydration(脱水).
Minorclinicalmanifestation:varyingdegreesofdisturbanceconsciousnessorcoma,unconspicuousDKA.06
Complications6.3
Infectiouscomplications
Pyogenicinflammation:
furuncle,carbuncle,pustule,etc.Fungalinfection:
tineapedis,tineacorporis,etc.
PulmonarytuberculosisFigure2:Infectiouscomplications06
Complications6.4
Macroangiopathy:
Themainhistopathological
changeisatherosclerosis
(AS).Itismostliketoaccompanywithaorta,coronaryartery,cerebralartery,renalartery
,peripheralartery,etc.TheASleadstoischemic
changesofheart,brain,kidneysandlimbs.
06
Complications6.5MicroangiopathyItisthespecificcomplicationsofDM.It’stypicalhistopathologicalchangesaremicrocirculationdisturbancesandthethicknessofbasalmembraneofvessel.Themicroangiopathymostliketoaffectsretina,nerves,nephridium,andmyocardium
06
Complications6.6
Neurologicalcomplications:
1)centralnervoussystemcomplication(CNSC):
alteredmentalstatus,ischemicstroke,seniledementia.2)peripheralneuropathy:paresthesia,decreasedofmuscle,areflexia3)autonomicneuropathy:gastroparesis,diarrhea,astriction,abnormalsweating.06
Complications6.7
Diabeticfoot
•Relatedtodistallowerneurologicaldisorderanddifferentlevelsperipheralvasculardisease.•Symptomsoflight:footabnormal,skincold,high-riskfoot•Severesymptoms:footulcer,necrosis•Diabeticfootisthemainreasonofdisabilityandamputation06
Complications6.8Otherdiseaseseyecomplications:suchasretinalmaculardisease,cataracts,glaucoma,Iridocyclitisskinlesions:likeSkininfections,skinitch,chappedskin,rash.Figure4:skinlesionsFigure3:eyecomplications2026/8/27Macroangiopathy大血管病变macro-largemicro-smallangi-arteries动脉血管-pathythesuffixof"diseases”Athersclerosis动脉粥样硬化ather/oplaqueoffattysubstance
动脉粥样-sclerosishardening硬化WordAnalysis2026/8/27Peripheralangiopathy周围血管病Peri-surrounding周angi-meansvessel-pathymeansdiseaseNeurological神经病学的Neur-meansnerve-ologicaldiscipline学科的Dementia痴呆De—脱,去,减,除,离-mentiaspiritWordAnalysis07
diagnosisFastingbloodglucosegreaterthanorequalto7mmol/L.Twohourspostprandialbloodglucosegreaterthanorequalto11.1mmol/L3)Thesymptomsofdiabetesandanytimeplasmaticglucosegreaterthanorequalto11.1mmol/L07
diagnosis7.1Type1diabetesmellitus1.Theageofonsetisyoung,theage<30yearsold.2.Thesymptomscomeonabruptly3.ThesymptomsofPolydipsia,PolyphagiaandPolyuriaareobvious.4.Thebloodglucoselevelishigh,andmanypatientswithketosisacidtoxicasthefirstsymptom.Lowserum
levelofinsulinandThelowlevelofCpeptide07
diagnosis7.2
Type2diabetesmellitusThecommonintheelderly,highincidenceofobesity,oftenaccompaniedbyhypertension,dyslipidemia
,atherosclerosisandotherdiseases.Insidiousonset,hasnoearlysymptoms,oronlymildfatigue,thirst,hyperglycemiaisnotobvious.GlucosetolerancetesttoconfirmthediagnosisSeruminsulinlevelinearlynormalorincreased,Theadvancedislow2026/8/27Plasmatic血浆的plasm-血浆-atic性质的Dyslipidemia血脂异常dys-不良的,困难lip-脂肪的-emia血症Gluc(o)葡萄糖
glucagon胰高血糖素
glucokinase葡萄糖激酶glucocorticoids糖皮质激素
enteroglucagon肠高血糖素WordAnalysis08
Antidiastole8.1
Liverdiseases:Livercirrhosis
patientsoftenhaveabnormalglucosemetabolism,thefastingbloodglucoseofthetypicalpatientisnormalorlow,postprandialbloodglucoseriserapidly.Thedurationoftheelderly,thefastingplasmaglucosecanalsobeelevated.2026/8/27DiabetshealtheducationMedicalnutritiontherapyConditionmonitoringDrugstherapy09Therapy09Therapy9.1MedicalnutritiontherapyCalculatethetotalquantityofheat;Nutrientcontent;Reasonabledistribution;Follow-up09Therapy9.2conditionmonitoringRegularchecksbloodsugartoadjustthetreatmentplanProperexerciseregularlyEveryyearortwocomprehensivereview,complications,earlydetectionandtreatment09Therapy9.3
DiabetshealtheducationMedicaistaffadheretofollowup,accordingtotheneedtoadjustthetreatmentplan;Lifeshouldberegular,quitsmokinganddring;Topreventinfection.09Thera
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