碘催化的有机化学反应

1、The Applications of Iodine as Catalyst in Organic Reaction,Content,The formation and cleavage of ether bond Acyl reaction Addition reaction Oxidation reaction Reductive reaction Rearrangement reaction,碘处于元素周期表第A 族的最下端,具有较大的原子半径和多层电子结构,使它除具有该族元素的通性外,还具有一定的特殊性质,如能催化有机化学反应,因而受到有机化学界的重视,醚键的形成和断裂,J. Org.

2、 Chem. 2001, 66, 7527-7529,A Convenient Method for Protection and Deprotection of Alcohols and Phenols as Alkylsilyl Ethers Catalyzed by Iodine Under Microwave Irradiation,Synth. Commun.,2003, 33, 4005.,2 酰化反应,在催化量的碘存在下伯、仲、叔醇或酚和乙酐反应也能高收率地得到乙酸酯,在无溶剂条件下反应速度更快,伯、仲醇和酚的酰化在几秒中就可完成。 碘甲醇体系在室温能选择性脱保护乙酸芳香酯,乙酸

3、烷基酯不被裂解。苯环上带有强吸电子基团如硝基、醛基、羧酸酯的乙酸芳基酯酯基也不被裂解。,Tetrahedron Letters 47 (2006) 40654068,1,1-二乙酸酯的生成反应,J. Org. Chem. 2006, 71, 8283-8286,Addition,Tetrahedron Letters Pergamon 44 (2003) 30013003,I2 as an efficient catalyst in ionic DielsAlder reactions of unsaturated acetals,Tetrahedron Letters 47 (2006) 4

4、5094512,Hosomi-Sakurai Reaction， allylation,J. Org. Chem. 2004, 69, 4005-4006,Tetrahedron Letters 40 (1999) 5923-5926,This method was only successful with cyclic allylic acetates.,Tetrahedron Letters 45 (2004) 65056507,iodine-catalyzed allylation and alkynylation of cyclic allylic acetates,Tetrahedr

5、on Letters 48 (2007) 39633967,Tetrahedron Letters 48 (2007) 81208124,Tetrahedron Letters Iodine-catalyzed allylation of 1,3-dicarbonyl compounds with allylic alcohols at room temperature,Synlett 2001, No. 10, 16381640,Synthesis 2003, No. 2, 247250,Yadav J S , Reddy B V S , Reddy M S. Synlett , 2003

6、, (11) :1722 1724,Michael addition,Wang S Y, Ji S J , Loh T P. Synlett , 2003 , (15) : 2377 2379 Tetrahedron Letters 48 (2007) 28672870,Tetrahedron Letters 47 (2006) 18891893,Tetrahedron 61 (2005) 1175111757,FriedelCrafts reaction,Tetrahedron Letters 48 (2007) 68816885,Tetrahedron Letters 47 (2006)

7、31273130,Tetrahedron , 2004 , 60 :2051 2055 Tetrahedron Lett . , 2003 , 44 : 1959 1961,Molecular iodine catalyzed synthesis of aryl-14Hdibenzo a, jxanthenes under solvent-free condition,Bioorganic Zareyee, D. Synthesis 2003, 1875.,N-Bromosuccinimide and Iodine Catalyzed Highly Efficient Deoxygenatio

8、n of Sulfoxides to Thioethers Using 3-Mercaptopropionic Acid under Mild Reaction Conditions,Singh J , Kaur I , Kaur J , et al . Synth. Commun. , 2003 , 33 :191 197,Speedy and Regioselective 1,2-Reduction of Conjugated a,b-Unsaturated Aldehydes and Ketones Using NaBH4/I2,Yanada R , Bessho K, Yanada K

9、. Synlett , 1995 , (5) : 443 444,芳香硝基化合物在催化量的碘作用下在THF, NH4Cl 水溶液中被钐还原为相应的伯胺,双键重排，构型翻转,J. Org. Chem. 2001, 66, 8135-8138,杂环的合成,Yadav J S , Reddy B V S , Hashim S R. J . Chem. Soc. , Perkin Trans. 1 , 2000 , (18) : 3082 3084,Tetrahedron 54 (I 998) 13485-13494,Iodine-Catalyzed Aziridination of Alkenes

10、using Chloramine-T as a Nitrogen Source,Kim KM, Jeon DJ , Ryu E K. Synthesis , 1998 , (6) : 835 836,A Convenient Synthesis of 2-Alkyl-2-methyltetrahydrofurans from 4-Methylalk-4-en-1-ols Catalyzed by Iodine,Bandgar B P , Bettigeri S V , Joshi N S. Synth. Commun. , 2004 , 34 : 1447 1453,Journal of Mole