参麦注射液与卡维地洛联用对扩张型心肌病的疗效.pdf

A5fhr胡凤梅,卜法芹12BBD=SnullTgnull453003nullnullK1nullnull观察参麦注射液与卡维地洛联合应用对扩张型心肌病(DCM)的疗效bZEnull选择NYHAnull-null级DCM患者,随即分为治疗组(63例)和对照组(58例)b对照组给予常规治疗加卡托普利12null5mg/d,渐加量至5075mg/d和卡维地洛2null5mg/d,渐加量至10mg/d,治疗组在上述治疗基础上,给予参麦注射液60ml加5%GnullS150ml静脉滴注,每日1次,15d为1疗程,共用1疗程bTnull治疗组在改善心功能方面优于对照组,总有效率分别为81null0%和65null5%,两组比较差异有统计学意义(P0null05)b用药后左心室射血分数(LVEF)a每搏量(SV)a每分钟排血量(CO)明显增加(P0null05,P0.01)bnull参麦注射液和卡维地洛在常规抗心力衰竭治疗的基础上,可明显改善临床症状和左心室收缩功能,增强了治疗作用,减少不良反应达到了协同治疗心力衰竭的目的b1oMnull参麦注射液；卡维地洛；心肌病；扩张型；心力衰竭ms|:R542null2nullnullDSM:BnullnullcI|:1672null3422(2010)13null0079null03EffectofShenmaiInjectionCombinedwithCarvedilolonPatientswithDilatedCardiomyopathyHUFengmei,BOFaqinTheFirstRongkangHospitalofHenan,Xinxiang453003,ChinaABSTRACTnullObjetivenullToobservetheeffectsofshenmaiinjectioncombinedwithcarvedilolonchronicheartfailureofdilatedcardiomyophathypatients.MethodsnullTotally121casesofdilatedcardionullmypathypatients.(NewYorkHeartAssociationfunctionalclassnullnull)wereselectedandthendividedinnulltoshenmaiinjectionacarvedilolgroups(63cases)andthecontrolgrouprandomly(58cases).Thecontrolgrouppatientsweretreatedwithroutinemethodcombinedwithcaptoprilandcarvedilo.lThetreatmentgroupwastreatedwithmethodcombinedwithcaptoprilandcarvedilolwiththesameglosesandregimeasthecontrolgroup,andplusshenmaiinjectionof60ml/d,addedby150mlof5%glucosesolutiononceadaybyiv.foracourseof15daysforonecourse.ResultsnullThetreatmentgroupwassuperiorinimprovingtheheartfunctionandthecontrolgroupthetotalefficacyratewas81null0%and65.5%respectively,thedifferencesweresignificantbetweentwogroups(P0null05).LVEFaSVandCOobviouslyincreasedafterusingmedicine(P0null05,P3null79nullnullJournalofMedicalForumnullVo.l31nullNo.13nullJuly2010null,VU4aa51,OPis(LVEF)45%,3y,V,#null.E$,svF(58)#5AF(63),-M-aYa8Ws,S,V(q50Q/s),SBP90mmHg(1mmHg=0null133kPa),DBP50mmHg,$,e,nulli.E,k%,h,/,$P#hfb1.2nullZEnullFB,eyaaKaaUa512null5mg/d,vF5075mg/dg；5V2null5mg/d7S,vF10mg/d；FvF$FA60mlF5%$A150ml,1Q,21b1.3null4Snull4F-#3m?,Pis(LVEF)ar(SV)as(CO)；?f,?2)Ar,1)r,rb1.4nulld9ZEnullSPSS13null0d9q,(nullS(nullxnulls)VU,F=FW1t_b2nullT2.1nullF?fnull?A,Aq23null8%(15)rq57null2%(36),rq19null0%(12),9rq81null0%(51),vF58,Aq19null0%(11),rq46null6%(27),rq34null4%(20),9rq65null5%(38)bF1sd9il(P0null05)b2.2nullF-3mSnullF0LVEFaSV#COA9F(P0null05,P0null01),nV1bV1nullDCM-?1null(nullxnulls)F(63)-vF(58)-LVEF0.2null0.20.4null0.1*null0.2null0.30.3null0.2*SV(ml)35.0null3.261.0null7.2*null33.0null6.549.0null4.0*CO(L/min)3.2null0.84.6null1.3*null3.3null0.13.8null0.5*nullnullnull-1；*P0null05,*P0null01；vF1；nullP0null013null)fhhy,haL.ya8A%f$h?h1,M?Ch8=nulls8/,P.1Gds,V7?h|2,?b#*d)9,7*d9#3T:nulls8|.；%33r3bHWwM,#F?3M,#b,5nullnulls8E4T,；?YV,hiSyEB0,4,4Pi?4bP559Vq5b7SP5V?3Yq1haCaVaaF6bA1sa,%V3ar,?P#,?bLV0:nullT,9l,k5E,Pk,9FA9,40?7；null45fQ,?,f?8；nullf3,9bV:A5a5DCMH,F?ZvF,9rqsY81null0%65null5%,FWsAil；60LVEFaSV#COA9F,AT,45fQ,?,#h55VCBVbqVaVC,5h5AVCqyaY；7a9%0s,#?ZT,0T,；hQ?3,rxb(83:)null80nullnull医药论坛杂志null2010年7月null第31卷null第13期nullPB,5D=FnullF)055null,?SF)0Pb04=,V?04S,s,041,0c,604#3VP4,(V?ADR?3b,5,D=P04H10P,HE0bV5V,5vsADRVC#q,C,-,VC；Q,hd,4vDi40f,f?3,InC0QbHF2dSb0g-5haka4HWZK,%0t?3qQBH4?C,0gW,?CaahnADR,1M1b7-,TBE)JD,ADR0fM1,1,T:D?Tv,HWAeAV,224ADR,50%iAApf；Q,DCQ3,V?DY#,3,b-FD10Q,T=,MT1,4,50bV,Bt#C0QHb?rSE,SaaSa(B*arADR67b1qaSaWb61,S(MbS-6,SyM1,yB*SSfADR6,hembID1null3,SEJ0S5.0QS5EJ.S0Y,2004,18(4):203.2null.,.2005M77QsJ.0h,2007,16(2):83.3nullPirmohamedM,Jamess,MeakinS,eta.l0Qy:18820h-QsJ.SD,2005,8(1):18null22.4null1=,f,.242QsJ.S0,2005,16(9):455.5null.,.270QsJ.SD0,2009,29(4):338.6nullf,U,u.5280QsJ.S0,2009,20(23):1809null1811.7null,.S0Q6eJ.S0Y,2005,19(9):5721.2010null05null07l(80:)ID1nullb,X,.fh=aB#5fnullMJ.+uD0,2000,12(1):36.2null5,2.fhM/,L=S:/.12.:3,2006:1576null1579.3nullFl,k.5#?YJ.=+Dv,2003,24:341null342.4nullO,.,HL,.B=MJ.=S,1999,38(5):306null308.5nullPackerM,CoatsAJ,FowlerMB,eta,lEffectofcarvenulldilolonsurvivalinseverechronicheartfailureJ.NEnglJMed,2001,344(22):1651null1658.6nullKrumH,ShustermanN,MacmahonS,eta.lEfficacyandSafetyofcarvedilolinpatientswithchronicheartfailurereceivingconcomitantamiodaronetherapyAustralia/NewZealandHeartFailureResearchCollobortiveGroupJ.JCardFa