早产林建华课件

Preterm Labor 早 产 Lin Jianhua M.D., Ph.D., Professor Department Of Obstetrics decreases free intracellular calcium ions nRitodrine (Yutopar) Same as terbutaline nNifedipine (Procardia) Calcium channel blocker nIndomethacin (Indocin) Prostaglandin inhibitor Potential Complications Associated With the Use of Tocolytic Agents : Magnesium sulfate Pulmonary edema Profound hypotension* Profound muscular paralysis* Maternal tetany* Cardiac arrest* Respiratory depression* Beta-adrenergic agents Hypokalemia Hyperglycemia Hypotension Pulmonary edema Arrhythmias Cardiac insufficiency Myocardial ischemia Maternal death Indomethacin (Indocin) Renal failure Hepatitis Gastrointestinal bleeding Nifedipine (Procardia) Transient hypotension nCorticosteroid Therapy nDexamethasone and betamethasone nfor fetal maturation reduces mortality, respiratory distress syndrome and intraventricular hemorrhage in infants between 28 and 35 weeks of gestation. n benefits start at 24 hours and last up to seven days after treatment nThe potential benefits or risks of repeated administration of corticosteroids after seven days are unknown. nwomen who received antibiotics sustained pregnancy twice as long as those who did not receive antibiotics n had a lower incidence of clinical amnionitis. n poor fetal outcome (death, respiratory distress, sepsis, intraventricular hemorrhage or necrotizing colitis) occurred less frequently in women receiving antibiotics THANKS FOR YOUR ATTENTION Lin Lin JianhuaJianhua M.D., Ph.D., ProfessorM.D., Ph.D., Professor Dep. of Dep. of ObstetObstet. & . & GynecolGynecol. . RenjiRenji Hospital