子宫颈癌cervicalcarcinoma.ppt

子宫颈癌cervicalcarcinoma,目录,1、相关生词2、子宫颈癌简介3、病理变化4、临床症状5、发病机制6、辅助检查7、治疗,相关生词：cervicalcarcinomasvklk:sinum子宫颈癌malignanttumormlgnnttju:m恶性肿瘤exfoliocytologyexaminationoncervixofuterussvksju:trs宫颈脱落细胞学检查precancerouslesionsprikns()rs癌前病变squamouscellcarcinomaskwems,k:sinum鳞状细胞癌adenocarcinoma,dn,ksnm腺癌erosivetypersv糜烂型cauliflowertypeklfla菜花型infiltratingtypeinfiltreiti浸润型ulcerativetypels,retv溃疡型vaginalsecretionsvdainlsikri:n阴道分泌物增多hyperfunction,haipfkn机能亢进hemorrhagicleucorrhealju:kuri:血性白带erosionirun侵蚀，腐蚀pelvicnervepelvik盆腔神经infiltrationoroppression,infiltreinpren浸润或压迫,invadenved侵犯hematuria,himtjr血尿bladdervaginafistulavdainfstjl膀胱阴道瘘pathogenesis,p()denss发病机制humanpapillomavirus(HPV),pplm人类乳头瘤病毒incubationperiod,inkjubein潜伏期fecundityfiknditi多育cervicallacerationsvkllsre()n宫颈裂伤thinprepcytologytest(TCT)saitldi液基薄层细胞检测biopsybai,psi活体组织检查fertilityftiliti生育能力hysterectomy,hstrektm子宫切除internallesionsint:nl内部病变radiotherapy,red()erp放射疗法recurrentrikrnt复发的；周期性chemotherapykem()erp化学疗法metastasismtstss转移atrophytrfi萎缩reversalriv:sl逆转prognosiseffectprnusis预后效果conservativetreatmentkns:vtiv保守治疗curativeeffectkjurtiv疗效,BriefIntroduction：Cervicalcarcinomaisthemostcommonmalignanttumorofthefemalereproductivesystem,andtheageofonsetis4060yearsold.Cervicalcanceristheleadingcauseofdeathinwomentumorabout50yearsago.Butinrecentlyyears,asthepromotionandpopularizationonaboutexfoliocytologyexaminationoncervixofuterus,alotofprecancerouslesionsandearlycancergetearlypreventionandcontrol,andcomparedwiththepast,advancedcancerissignificantlyreduced,and5yearsofsurvivalandcurerateissignificantlyincreased.,简介：子宫颈癌是女性生殖系统最常见的恶性肿瘤之一，发病年龄以4060岁居多。50年前，子宫颈癌是女性肿瘤死亡的主要原因，近年由于子宫颈脱落细胞学检查的推广和普及，使许多癌前病变和早期癌症得到早期防治，晚期癌较过去明显减少，5年生存率和治愈率显著提高。,PathologicalChange:Squamouscellcarcinomaismorecommonthanadenocarcinoma,accountingfor8090.Therefourtypesofcervicalcarcinoma,erosivetype,cauliflowertype,infiltratingtype,andulcerativetype.病理变化：以鳞状细胞癌居多，约占8090，其次为腺癌。有糜烂型、外生菜花型、内生浸润型、溃疡型四种。,Clinicalsymptoms：1、Vaginalsecretionsincrease.Atthebeginningofthecervicalcarcinoma,cancerstimulatecervicalglandsandthesecretionfunctionishyperfunction.临床症状：1、阴道分泌物增多。初期由于癌的存在刺激宫颈腺体分泌功能亢进。2、Irregularvaginalbleeding.Ontheinitialstage,thereisasmallamountofhemorrhagicleucorrheaandcontactsexvaginalbleeding.Afteradvancedcancererosionlargebloodvessels,cancausealargenumberoffatalvaginalbleeding,2、阴道不规则流血早期表现为少量血性白带及接触性阴道流血，晚期癌肿侵蚀大血管后，可引起致命的大量阴道流血。3、Pain.Painisthesymptomofadvancedcervicalcancer.Thecauseofpainismainlybecauseofthetumorinfiltrationoroppressiontopelvicnerve.3、疼痛。为晚期宫颈癌的症状。产生疼痛的原因，主要是由于盆腔神经受到癌肿浸润或压迫。,4、othersymptoms.Whentheadvancedcervicalcancerinvadesurinarybladder,cancausefrequenturination,urinarypainorhematuria,evencausingbladdervaginafistula.4、其他症状。晚期宫颈癌侵犯膀胱时，可引起尿频、尿痛或血尿，甚至发生膀胱阴道瘘。,Pathogenesis：CervicalcanceriscausedbytheHumanpapillomavirus(HumanPapillomavirus,orHPV).HPVcanbetransmitteddirectlythroughtheskincontact,whichhasmorethantenyearsofincubationperiod,sothereisnosymptomsontheinitialstage.Inaddition,ithasarelationtoearlymarriage,fecundity,cervicallacerationandsoon.发病机制：子宫颈癌是由人类乳头瘤病毒（HumanPapillomaVirus，简称HPV）引起的，HPV病毒可直接通过皮肤接触传播，有十几年的潜伏期，故初期没有任何症状.此外，还与早婚、多产、宫颈裂伤等有关。,Assistantexamination:1、HPVandTCT.HPVistheshortforHumanPapillomaVirus.AndsometypesofHPVcanleadtocervicalcancer.TCTistheshortforThinprepcytologytest,anditsthemostadvancedcervicalcytologyinspectiontechnologyintheworld.Inaddition,Ultrasonicphaninspection,laboratoryexamination,theDiagnosisofXrayandbiopsyareothercommonexaminations.辅助检查：1、HPV检查和TCT检查。HPV检查：HPV是指人乳头瘤状病毒，某些类型的HPV可以导致子宫颈癌。TCT检查：TCT是液基薄层细胞检测的简称，它是目前国际上最先进的一种宫颈癌细胞学检查技术2、超声显象检查3、实验室检查4、X线诊断5、活体组织检查,Treatment：Forthepatientswhoneverbeared,generallyitneedstoreservefertilityandregularlyfollow-uptopreventrecurrence.Forthefemalewhohasgivenbirth,thegeneralconsiderationishysterectomy.治疗：对于未生育的患者，一般可以酌情保留生育能力，定期随访防止复发；对于已经生育过的女性，一般考虑子宫切除。1、Thesurgicaltreatmentofthecervicalcancer.Forearlycericalcancer,theusuallytreatmentistoremovetheinternallesionspart;Formiddle-latecancerwhichdidntdiffusion,canconsiderhysterectomyandpartofitsaccessories.子宫颈癌的手术治疗。早期的子宫颈癌，可以切除内部病变部分；中晚期癌未扩散的，可考虑切除子宫及其部分附件。,2、Cericalcancerradiotherapy.Foradvancedcancer,andrecurrentcarcinoma,generallydidntconsidersurgicallyremovingcompletely,usingradiationtherapyandchemotherapy.Forhysterectomypatients,canbeasadjuvanttherapytoputanendtothetumorrecurrenceandmetastasis.子宫颈癌的放射疗法。对于晚期癌，及复发癌，一般不通过手术彻底切除，采用放射治疗及化疗。对于切除子宫的患者，可在手术后，作为辅助疗法，杜绝肿瘤的复发与转移。,3、Cervicalcancerofhormonetherapy.Thehormonetherapytreatmentcanmaketumoratrophy,reversal.Forpulmonarymetastasisorrecurrence,advancedcervicalcancerpatients,hormonetreatmenteffectisgood.子宫颈癌的激素治疗。采用雄激素治疗能够促使肿瘤萎缩、逆转。对于肺转移、晚期或复发子宫颈癌患者，激素治疗的效果较好。,Forthecericalcancertreatment,thoughoperationmethodofbodymaydamagetopatients,butprognosiseffectisgenerallygood.Hormoneandradiationalsotohavecertainsideeffects,andtheyareconservativetreatm