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1、case report abdominal compartment symdrom in a patient with severe acute pancreatitis admissiona 56-year-old male was admitted to sicu of research institute of general surgery, jinling hospital on 20th oct 2003he sufferd from epigastric pain for two days, dyspnea and decreased urine output for one d

2、ay after a fat rich dietpe on admissiont 38, hr 140bpm, rr 30/min, bp 82/58mmhg oxygen saturation 92%acute face with shortness of breath, in agitated state, far distended abdomen with high tension, signs of diffusive peritonitis, weak bowel soundsbloody ascites was drawn out by diagnostic punctureur

3、ine output decreased further and anuria developed lab examination on adhb 18g/dl wbc 11300/mm3( n0.88 l0.09) platelet 95000/mm3 amy(serum) 1270u/l amy(urine)14819 lipase 10003u/l ca 1.9mmol/lbun 49mg/dl scr 4.0mg/dl arterial blood gas analysis:ph 7.26, pao2 55mmhg, paco2 28 mmhg, be 14.5mmol/lct: di

4、ffusive necrosis of pancreas, massive ascites, left pleural effusiondiagnosissevere acute pancreatitisardsarfshockabdominal compartment syndrometreatmentintubation, tracheostomy,mechanical ventilationfluid resuscitation and anti-shock therapy intraabdominal irrigation by laparoscopy, continous drain

5、ing by persistent negative pressure continuous venovenous high volume hemofiltrationanti-acid therapy and inhibition of pancreatic secretion prophylactic antibiotic therayadvancement of the illness and outcome of the patient3rd hospital day, developed “abdominal compartment syndrome ”, and received

6、the 2nd emergent operation as abdominal opening and gastrointestinal fistulization to relieve the abdominal high pressureintraabdominal pressure were indirectly measured by bladder pressure measurement. nhe experienced massive abdominal hemorrhage for two times, and even the 3rd emergent operation w

7、as performed for hemostasis and necrosis tissue cleaningnvarious microbials were recurrently found in the culture of the specimen of blood, sputum, secretion of wound, the tips of central venous catheter, and the fluid drained from the abdomen advancement of the illness and outcome of the patient14t

8、h day, intestinal function partially recovered and tpn was gradually switched to enteral nutrition 28th day, cvvh discontinued, urine output increased to more than 2000ml/d . 36th day, mechanical ventilation ceasedserum creatinine returned to normal range on 48th day39th day, and 57th day, received

9、two times of postage stamp autodermoplasty for skin defect in abdomen 161st day, after a ct scan confirming that pancreatic necrosis and effusion well absorbed, discharged 腹腔内压力的变化(膀胱测压法)腹腔内压力的变化(膀胱测压法) 吸入氧浓度和血气的变化吸入氧浓度和血气的变化心率的变化心率的变化 尿量的变化尿量的变化map,hr changes and dopamine/noradrenine dose adjustmen

10、t pao2/fio2 changesurine output and bun, scr changes during cbp012345671 13 35 57 79 911111313151517171919212123232525272729293131333335353737393941414343010203040506070bun(mg/dl)bun(mg/dl)chvhf(4l/h)cvvh(2l/h)cvvh discontinued012345671 13 35 57 79 911111313151517171919212123232525272729293131333335

11、353737393941414343010203040506070urine(l/d)urine(l/d)scr(mg/dl)scr(mg/dl)serum electrolytes changes during chvhf1001101201301401501 12 23 34 45 56 67 78 89 91010012345678k(mmol/l)1001101201301401501 12 23 34 45 56 67 78 89 91010012345678na(mmol/l)na(mmol/l)chvhf dayarterial ph changes during chvhf7.207.257.307.357.407.457.501 12 23 34 45 56 67 78 89 91010chvhf dayarterial pharterial hco3- and be level changes during chvhf-20-20-10-100 01010202030301 12 23 34 45 56 67 78 89

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