Bucladesine-calcium-salt-Dibutyryl-cAMP-calcium-salt-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEBucladesine calcium saltCat. No.: HY-B0764ACAS No.: 938448-87-4Synonyms: Dibutyryl-cAMP calcium salt; DC2797 calcium salt分式: CHCa.NOP分量: 488.42作靶点: PKA作通路: Protein Tyrosine Kinase/RTK; Stem Cell/Wnt储存式: Powder -20C 3 years4C 2 y

2、earsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O : 100 mg/mL (204.74 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 2.0474 mL 10.2371 mL 20.4742 mL5 mM 0.4095 mL 2.0474 mL 4.0948 mL10 mM 0.2047 mL 1.0237 mL 2.0474 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注

3、意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Bucladesine calcium salt (Dibutyryl-cAMP calcium salt; DC2797 calcium salt)是PKA选择性且细胞可通透激动剂。REFERENCES1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE1. Sharifzadeh, M., et al., Post-training intrahippocampal infusion of nicotine-bucladesine combination causes a s

4、ynergistic enhancementeffect on spatial memory retention in rats. Eur J Pharmacol, 2007. 562(3): p. 212-20.2. Azami, K., et al., The quantitative evaluation of cholinergic markers in spatial memory improvement induced by nicotine-bucladesinecombination in rats. Eur J Pharmacol, 2010. 636(1-3): p. 10

5、2-7.3. Mafune, E., M. Takahashi, and N. Takasugi, Effect of vehicles on percutaneous absorption of bucladesine (dibutyryl cyclic AMP) innormal and damaged rat skin. Biol Pharm Bull, 1995. 18(11): p. 1539-43.4. Rundfeldt, C., et al., The stable cyclic adenosine monophosphate analogue, dibutyryl cyclo-adenosine monophosphate (bucladesine), isactive in a model of acute skin inflammation. Arch Dermatol Res, 2012.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-379