Pancuronium-dibromide - nAChR Antagonist - 生命科学试剂 - MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEPancuronium dibromideCat. No.: HY-B0429CAS No.: 15500-66-0分式: CHBrNO分量: 732.67作靶点: nAChR作通路: Membrane Transporter/Ion Channel; Neuronal Signaling储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 H2O

2、 : 200 mg/mL (272.97 mM)* means soluble, but saturation unknown.Mass Solvent1 mg 5 mg 10 mg Concentration制备储备液1 mM 1.3649 mL 6.8244 mL 13.6487 mL5 mM 0.2730 mL 1.3649 mL 2.7297 mL10 mM 0.1365 mL 0.6824 mL 1.3649 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。BIOLOGICAL ACTIVITY物活性 Pancuronium Dibromi

3、de是竞争性 AChR 拮抗剂，IC50 为 5.5 nM。REFERENCES1. Fryer, A.D. and J. Maclagan, Pancuronium and gallamine are antagonists for pre- and post-junctional muscarinic receptors in theguinea-pig lung. Naunyn Schmiedebergs Arch Pharmacol, 1987. 335(4): p. 367-71.1/2 Master of Small Molecules 您边的抑制剂师www.MedChemE2.

4、Maestrone, E., et al., Extracellular pancuronium affects sodium current in chick embryo sensory neurones. Br J Pharmacol, 1994.111(1): p. 283-7.3. Lowenick, C.V., et al., Open channel and competitive block of nicotinic receptors by pancuronium and atracurium. Eur J Pharmacol,2001. 413(1): p. 31-5.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792;Fax: