种植体设计及其对骨结合的影响

年 骨结合失败／骨吸收病年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 种植系统的分年 软组织水平种植STRAUMANNSeptember04, 年 骨水平种植STRAUMANNSeptember04, 年 Straumann种植系S

STRAUMANNSeptember04, 年 :1种植体表 234 34 穿龈光滑表面／平台转移／非生物学间两种表面：适合不同组织接触和连STRAUMANNSeptember04, 年 : 234 234 穿龈光滑表面／平台转移／非生物学间两种表面：适合不同组织接触和连STRAUMANNSeptember04, 年 : 连接 34 34 穿龈光滑表面／平台转移／非生物学间两种表面：适合不同组织接触和连STRAUMANNSeptember04, 年 连接 3 严格疲劳强度测试、牙槽脊顶横向水平受力 应力分散结构设:摩尔氏锥形／十字锁合锥4 穿龈4 穿龈光滑表面／平台转移／非生物学间两种表面：适合不同组织接触和连STRAUMANNSeptember04, 年 1 2连接3严格疲劳强度测试、牙槽脊顶横向水平受力应力分散结构设:摩尔氏锥形／十字锁合锥4穿龈光滑表面／平台转移／非生物学间两种表面：适合不同组织接触和连STRAUMANNSeptember04, 年 1 2连接3严格疲劳强度测试、牙槽脊顶横向水平受力应力分散结构设:摩尔氏锥形／十字锁合锥4穿龈光滑表面／平台转移／非生物学间5光滑STRAUMANNSeptember04, 年 年 STRAUMANNSeptember04, 年 骨结合的过 年 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 SLAtivevs.STRAUMANNSeptember04, 年 SLAtivevs. STRAUMANNSeptember04, 年 SLAtivevs. Dip 2STRAUMANNSeptember04,

2年 -关于即刻负载的陈 ClearanceforImm. 1997, 2005,K0530881999,ClearanceforImm.ImmediateFunction2003, 2005,K0530882005,*ThesurfaceTiUnitewasclearedin1999,atthattimetheclearanceincludedimmediateloadinginsinglestageonly,whenatleast4im ntswereusedandsplintedwithabarintheanterioronly.In2005immediateloadingexpandedtobothsingleandtwostage,theanteriorlimitationwasremovedandastatementthatTiUnitewasindicated

√√√

WithgoodprimarystabilityandappropriateocclusalloadingWhen35Ncmtorqueis**certain ntlinesareSTRAUMANNSeptember04, 年 -关于即刻负载的陈 ClearanceforImm. 1997, 2005,K0530881999,ClearanceforImm.ImmediateFunction2003, 2005,K0530882005,*ThesurfaceTiUnitewasclearedin1999,atthattimetheclearanceincludedimmediateloadinginsinglestageonly,whenatleast4im ntswereusedandsplintedwithabarintheanterioronly.In2005immediateloadingexpandedtobothsingleandtwostage,theanteriorlimitationwasremovedandastatementthatTiUnitewasindicated

√√√

WithgoodprimarystabilityandappropriateocclusalloadingWhen35Ncmtorqueis**certain ntlinesareSTRAUMANNSeptember04, 年 -关于即刻负载的陈 ClearanceforImm. 1997, 2005,K0530881999,ClearanceforImm.ImmediateFunction2003, 2005,K0530882005,*ThesurfaceTiUnitewasclearedin1999,atthattimetheclearanceincludedimmediateloadinginsinglestageonly,whenatleast4im ntswereusedandsplintedwithabarintheanterioronly.In2005immediateloadingexpandedtobothsingleandtwostage,theanteriorlimitationwasremovedandastatementthatTiUnitewasindicated

√√√

WithgoodprimarystabilityandappropriateocclusalloadingWhen35Ncmtorqueis**certain ntlinesareSTRAUMANNSeptember04, 年 -关于即刻负载的陈 ClearanceforImm. 1997, 2005,K0530881999,ClearanceforImm.ImmediateFunction2003, 2005,K0530882005,*ThesurfaceTiUnitewasclearedin1999,atthattimetheclearanceincludedimmediateloadinginsinglestageonly,whenatleast4im ntswereusedandsplintedwithabarintheanterioronly.In2005immediateloadingexpandedtobothsingleandtwostage,theanteriorlimitationwasremovedandastatementthatTiUnitewasindicated

√√√

WithgoodprimarystabilityandappropriateocclusalloadingWhen35Ncmtorqueis**certain ntlinesareSTRAUMANNSeptember04, 年 126-8126-83-4STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 SLA物理表面形STRAUMANNSeptember04, 年 SLA物理表面形亲水STRAUMANNSeptember04, 年 SLA物理表面形亲水化学活STRAUMANNSeptember04, 年 SLActiveStudyin1M.de2ConceptofF.Ruppet3EnhancedproteinadsorptiononL.Scheideler/F.Ruppet4EnhancedproteinadsorptiononR.SeibletEarlycell5EnhancedcellactivityandG.Zhaoet6IncreasedcellA.Schedle/X.Rausch-FanetEarlybone7EnhancedbonehealingaftercontactwithJ.Becker/F.Schwarzet8Moreboneonsurface(BICD.Buseret9 S.J.FergusonetM.Bornstein/D.CochranetImntstabilityinM.Bornstein/D.CochranetClinicalcomparisonofimmediatevs.earlyMulticenterstudy:A.ZöllneretClinicalevaluationofsofttissueFieldtrial:D.Buser/D.Mortonet ntstability(RCT):SLAvs.T.W.OatesetEarlyloadingofSLActive ntsinlowdensityM.Roccuzzo/T.G.Wilson,STRAUMANNSeptember04, 年 SLActiveStudyM.de2ConceptofF.Ruppet3EnhancedproteinadsorptiononL.Scheideler/F.Ruppet4EnhancedproteinadsorptiononR.SeibletEarlycell5EnhancedcellactivityandG.Zhaoet6IncreasedcellA.Schedle/X.Rausch-FanetEarlybone7EnhancedbonehealingaftercontactwithJ.Becker/F.Schwarzet8Moreboneonsurface(BICD.Buseret9 S.J.FergusonetM.Bornstein/D.CochranetImntstabilityinM.Bornstein/D.CochranetClinicalcomparisonofimmediatevs.earlyMulticenterstudy:A.ZöllneretClinicalevaluationofsofttissueFieldtrial:D.Buser/D.Mortonet ntstability(RCT):SLAvs.T.W.OatesetEarlyloadingofSLActive ntsinlowdensityM.Roccuzzo/T.G.Wilson,STRAUMANNSeptember04, 年 SLActiveStudyM.de2ConceptofF.Ruppet3EnhancedproteinadsorptiononL.Scheideler/F.Ruppet4nhancedproteinadsorptiononSLActive市时R.SletEarlycell5EnhancedcellactivityandG.Zhaoet6IncreasedcellA.Schedle/X.Rausch-FanetEarlybone7EnhancebonehealingafterontactwithSActive表BSchw8Moreboneonsurface(BICD.Buseret9 S.J.FergusonetM.Bornstein/D.CochranetImntstabilityinM.Bornstein/D.CochranetClinicalcomparisonofimmediatevs.earlyMulticenterstudy:A.ZöllneretClinicalevaluationofsofttissueFieldtrial:D.Buser/D.MortonetComparisonof ntstability(RCT):SLAvs.T.W.OatesetEarlyloadingofSLActive ntsinlowdensityM.Roccuzzo/T.G.Wilson,STRAUMANNSeptember04, 年 SLActiveSLASTRAUMANNSeptember04, 年 Day Day Day14 GapbetweensofttissueandSLA nt No Directbloodsupply

CollagenfiberstotheSTRAUMANNSeptember04,2009BeckerJ,SchwarzF(Heinrich-HeineUniversity,Düsseldorf, ClinOralInvest(2007)11:245-年 诱导骨形 Week Week

STRAUMANNSeptember04,

BeckerJ,SchwarzF(Heinrich-HeineUniversity,Düsseldorf, JClinPeriodontol2007;34:78-年 诱导骨形 Week Week 0% 5%

27%BIC(p<0.001):BoneregenerationstartedaroundSLActive

80%BIC(p<0.001):Defectcomple filledafter12weeksSTRAUMANNSeptember04,

BeckerJ,SchwarzF(Heinrich-HeineUniversity,Düsseldorf, JClinPeriodontol2007;34:78-年 GBR与SLActive的表面对骨形Bone +Bone+STRAUMANNSeptember04,

BeckerJ,SchwarzF(Heinrich-HeineUniversity,Düsseldorf, Datapresentedat15thAnn.Sci.MeetingoftheEAO,Zurich,年 Week

BoneNewSTRAUMANNSeptember04,

BeckerJ,SchwarzF(Heinrich-HeineUniversity,Düsseldorf, Datapresentedat15thAnn.Sci.MeetingoftheEAO,Zurich,年 Example:references ntsurfaceAlbrektssonT,BranemarkPI,HanssonHA,LindstromI.Osseointegratedtitaniumim nts.ActaOrthopScand1981;52:155-170.ÅstrandP,EngquistB,AnzénB,BergendalT,HallmanM,KarlssonU,KvintS,LysellL,RundcrantzT.Nonsubmergedandsubmergedim ntsinthetreatmentofthepartiallyedentulousmaxilla.ClinIm ntDentRelatRes2002;4:115-BoioliLT,PenaudJ,MillerN.Ameta- assessmentofosseointegrationestablishmentandevolutionofsubmergedandnon-submergedendosseoustitaniumoralim nts.ClinOralIm ntsRes2001;12:BoyanBD,HummertTW,DeanDD,SchwartzZ.Roleofmaterialsurfacesinregulatingboneandcartilagecellresponse.Biomaterials1996;17:137-146.BoyanBD,BatzerR,KieswetterK,LiuY,CochranDL,Szmukler-MonclerS,DeanDD,SchwartzZ.TitaniumsurfaceroughnessaltersresponsivenessofMG63osteoblast-likecellsto1alpha,25-(OH)2D3.JBiomedMaterRes1998;39:77-85.BuserD,SchenkRK,SteinemannS,FiorelliniJP,FoxCH,StichH.Influenceofsurfacecharacteristicsonboneintegrationoftitaniumim nts.Ahistomorphometricstudyinminiaturepigs.JBiomedMaterRes1991;25:BuserD,BrogginiN,WielandM,SchenkRK,DenzerAJ,CochranDL,HoffmannB,LussiA,SteinemannSG.EnhancedboneappositiontoachemicallymodifiedSLAtitaniumsurface.JDentRes2004;83:529-533.

CochranDL,BuserD,tenBruggenkateCM,WeingartD,TaylorTM,BernardJ-P,PetersF,SimpsonJP.TheuseofreducedhealingtimesonITIim ntswithasandblastedandacid-etched(SLA)surface:earlyresultsfromclinicaltrialsonITISLAim nts.ClinOralIm ntsRes2002;13:144-153.CooperLF,MasudaT,WhitsonSW,YliheikkilaP,FeltonDA.Formationofmineralizingosteoblastculturesonmachined,titaniumoxidegrit-blasted,and sprayedtitaniumsurfaces.IntJOralMaxillofacIm 1999;14:37-47.DegidiM,ArteseL,ScaranoA,PerrottiV,GehrkeP, liA.Infl toryinfiltrate,microvesseldensity,nitricoxidesynthaseexpression,vascularendothelialgrowthfactorexpression,andproliferativeactivityinperi- ntsofttissuesaroundtitaniumandzirconiumoxidehealingcaps.JPeriodontol2006;77:73-80.FergusonSJ,BrogginiM,WielandM,deWildM,RuppF,Geis-GerstorferJ,CochranDL,BuserD.Biomechanicalevaluationoftheinterfacialstrengthofachemicallymodifiedsandblastedandacid-etchedtitaniumsurface.JBiomedMaterResA2006;78:291-297.IezziG,DegidiM,ScaranoA,PerrottiV,Piat liA.Boneresponsetosubmerged,unloadedim ntsinsertedinpoorbonesites:ahistologicalandhistomorphometricalstudyof8titaniumim ntsretrievedfromman.JOral ntol2005;31:225-233.KieswetterK,SchwartzZ,HummertTW,CochranDL,SimpsonJ,DeanDD,BoyanBD.Surfaceroughnessmodulatesthelocalproductionofgrowthfactorsandcytokinesbyosteoblast-likeMG63cells.JBiomedMaterRes1996;32:55-63.

RuppF,ScheidelerL,OlshankaN,deWildM,WielandM,Geis-GerstorferJ.Enhancingsurface energyandhydrophilicitythroughchemicalmodificationofmicrostructuredtitaniumim ntsurfaces.JBiomedMaterResA2006;76:323-334.SchwarzF,HertenM,SagerMWielandM,DardM,BeckerJ.Histologicalandimmunohistochemical ofveryearlyperiim nttissuereactionstochemicallymodifiedandconventionalSLAtitaniumim nts.Apilotstudyindogs.ClinOralIm ntsRes2007b;inpress.SchwarzF,HertenM,SagerM,WielandM,DardM,BeckerJ.Boneregenerationindehiscence-typedefectsatchemicallymodified(SLActive)andconventionalSLAtitaniumim nts:apilotstudyindogs.JClinPeriodontol2007a;34:78-86.SennerbyL,PerssonLG,BerglundhT,WennerbergA,LindheJ.Im ntstabilityduringinitiationandresolutionofexperimentalperiim ntitis:anexperimentalstudyinthedog.ClinIm ntDentRelatRes2005;7:136-140.ZhaoG,SchwartzZ,WielandM,RuppF,Geis-GerstorferJ,CochranDL,BoyanBD.Highsurfaceenergyenhancescellresponsetotitaniumsubstratemicrostructure.JBiomedMaterResA2005;74:49-58.STRAUMANNSeptember04, 年 年 年 年 生物学缝7,07TheInternationalJournalofPeriodontics&RestorativeDentistry,Vol.135 年 非生物学缝0,6±0,3µm 年 非生物学缝0,6±0,3µm 年 E.colibacteria 年 年 年 连接缝隙：生物学缝隙／非生物学缝 年 连接缝隙：生物学缝隙／非生物学缝 年 连接缝隙：生物学缝隙／非生物学缝→生物学缝隙（细菌的存留空间 年 连接缝隙：生物学缝隙／非生物学缝→生物学缝隙（细菌的存留空间→细菌的存 年 连接缝隙：生物学缝隙／非生物学缝→生物学缝隙（细菌的存留空间→细菌的存 年 年 Straumann种植系 S

年

STRAUMANNSeptember04, 年

STRAUMANNSeptember04, 年

STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 ISO14801testInternationalWorstcasescenario(3mmbone (axial&

sinusoid(Woehlercurve)2Hz0.9%NaCl/372×NormtestingabutmentSTRAUMANNSeptember04, 年 BLØ4.8mm,

BoneMarketSTRAUMANNSeptember04, 年 ISO14801testInternationalWorstcasescenario(3mmbone (axial& Load:singlepushuntilNormtestingabutmentSTRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 STRAUMANNSeptember04, 年 Example:references“biomechanical ntAbrahamssonI,BerglundhT.Tissuecharacteristicsatmicrothreadedim nts:anexperimentalstudyindogs.Clin ntDentRelatRes2006;8:107-113.AssenzaB,ScaranoA,LeghissaG,CarusiG,ThamsU,SanRomanF,Piat liA.Screwvscement-im restorations:anexperimentalstudyinthebeagle.Part1.Screwandabutmentloosening.JOralIm ntol2005;31:BambiniF,MemeL,PellechiaM,SabatucciA,SelvaggioR. ysisofdeformationoftwoim connectionsystemsduringim ntinsertion.Aninvitrostudy.MinervaStomatol2005;54:129-138.ChouC-T,MorrisHF,OchiS,WalkerL,DesRosiersD.AICRG,PartII:CrestalbonelossassociatedwiththeAnkylos nt:loadingto36months.JOralIm ntol2004;30:134-ChunH-J,ShinH-S,HanC-H,LeeS-H.Influenceofim abutmenttypeonstressdistributioninboneundervariousloadingconditionsusingfiniteelement ysis.IntJOralMaxillofacIm nts2006;21:195-202.EngelkeW,DeccoOA,RauMJ,MassoniMCA,SchwarzwällerW.Invitroevaluationofhorizontalim micromovementinbonespecimenwithcontactendoscopy. ntDent2004;13:88-94.HanssonS.Theim ntneck:smoothorprovidedwithretentionelements.Abiomechanicalapproach.ClinOral ntsRes1999;10:394-405.HanssonS.Im nt-abutmentinterface:biomechanicalstudyofflat-topversusconical.ClinIm ntDentRelatRes2000;2:HanssonS.Aconicalim nt-abutmentinterfaceatthelevelofthemarginalboneimprovesthedistributionofstressesinthesupportingbone.Anaxisymmetricfiniteelement ClinOralIm ntsRes2003;14:286-293.HeckerDM,EckertSE,ChoiY-G.Cyclicloadingofim supportedprostheses:comparisonofgapsattheprosthetic-abutmentinterfacewhencycledabutmentsarere cedwithas-manufacturedabutments.JProsthetDent2006;95:26-32.

HoyerSA,StanfordCM,BuranadhamS,FridrichT,WagnerJ,GrattonD.Dynamicfatiguepropertiesofthedentalim abutmentinterface:jointopeninginwide-diameterversusstandard-diameterhex-typeim nts.JProsthetDent2001;85:599-607.JemtT.Measurementsoftoothmovementinrelationto ntrestorationsduring16years:acasereport.Clin ntDentRelatRes2005;7:200-208.KingGN,HermannJS,SchoolfieldJD,BuserD,CochranDL.Influenceofthesizeofthemicrogaponcrestalbonelevelsinnon-submergeddentalim nts:aradiographicstudyinthecaninemandible.JPeriodontol2002;73:1111-1117.KhraisatA,StegaroiuR,NomuraS,MiyakawaO.Fatigueoftwoim nt/abutmentjointdesigns.JProsthetDent2002;88:604-KitagawaT,TanimotoY,OdakiM,NemotoK,AidaM.Influenceofim nt/abutmentjointdesignsonabutmentscrewlooseninginadentalim ntsystem.JBiomedMaterResBApplBiomater2005;75B:457-463.Lioubavina-HackN,LangNP,KarringT.Significanceofprimarystabilityforosseointegrationofdentalim OralIm ntsRes2006;17:244-250.MaedaY,SatohT,SogoM.Invitrodifferencesofstressconcentrationsforinternalandexternal-hexim connections:ashortcommunication.JOralRehab2006;33:MayKB,EdgeMJ,RussellMM,RazzoogME,LangBR.Theprecisionoffitattheim ntprosthodonticinterface.JProsthetDent1997;77:497-502.MorrisHF,WinklerS,OchiS.TheAnkylosendosseousdental nt:assessmentofstabilityupto18monthswiththePeriotest.JOralIm ntol2000;26:291-299.MorrisHF,WinklerS,OchiS,KanaanA.Anewim designedto izecontactwithtrabecularbone:survivalto18months.JOralIm ntol2001;27:164-173.MorrisHF,OchiS,CrumP,OrensteinIH,WinklerS.AICRG,PartI:A5-yearmulticentered,multidisciplinaryclinicalstudyofanewandinnovativeim ntdesign.JOralIm ntol2004a;30:125-133.

MorrisHF,OchiS,OrensteinIH,PetrazzuoloV.AICRG,PartV:Factorsinfluencingim ntstabilityat cementandtheirinfluenceonsurvivalofAnkylosim nts.JOralIm 2004b;30:162-170.MotoyoshiM,YanoS,TsuruokaT,ShimizuN.Biochemicaleffectofabutmentonstabilityoforthodonticmini-im nt.Afiniteelement ysis.ClinOralIm ntsRes2005;16:NortonMR.Aninvitroevaluationofthestrengthofaninternalconicalinterfacecomparedtoabuttjointinterfaceinim design.ClinOralIm ntsRes1997;8:290-298.NortonM