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2025年医学外语考试题及答案医学外语考试(2025年)第一部分:听力理解(共20分)SectionA(短对话,10分)听下面5段短对话,每段对话后有1个小题,从A、B、C三个选项中选出最佳选项。每段对话读两遍。1.对话内容:Patient:"Doctor,I’vehadapersistentcoughfortwoweeks,andit’sgettingworseatnight.Ialsofeelabitshortofbreathwhenclimbingstairs."Doctor:"Letmecheckyourrespiratoryratefirst.18breathsperminute,whichisnormal.Doyouhaveanyfeverorchestpain?"Patient:"Nofever,butthere’sadullachebehindthesternumwhenIcoughhard."问题:WhatsymptomdoesthepatientNOTmention?A.NighttimecoughB.ChestpainduringcoughingC.Highfever2.对话内容:Nurse:"Mr.Lee,yourbloodtestresultsareback.Thewhitebloodcellcountis15×10⁹/L(normalrange4-10×10⁹/L),andC-reactiveproteinis45mg/L(normal<10mg/L)."Patient:"Whatdoesthatmean,nurse?AmIinfected?"Nurse:"Itindicatesanacuteinflammatoryresponse.Thedoctorwillprescribeantibiotics,butweneedtowaitforthesputumcultureresulttoconfirmthepathogen."问题:Whatisthenurse’ssuggestionbasedonthetestresults?A.ImmediatesurgeryB.WaitingforsputumculturebeforeantibioticuseC.StartingantiviralmedicationSectionB(长对话,10分)听下面1段长对话,对话后有5个小题,从A、B、C三个选项中选出最佳选项。对话读两遍。对话内容:Doctor:"Ms.Chen,let’sreviewyourfollow-upafterthetotalkneereplacementsurgerythreemonthsago.How’syourmobilitynow?"Patient:"Icanwalkwithoutacanemostofthetime,butthere’sstillswellingaroundtheknee,especiallyafterstandingformorethan30minutes.Andtherangeofmotionislimited—maybe90degreeswhenbending,notthe120degreesthephysicaltherapistaimedfor."Doctor:"Let’schecktheincisionsitefirst.Itlookshealedwell,norednessordischarge.TheX-rayshowstheprosthesisisproperlyaligned.Theswellingcouldbeduetoresidualinflammation;wecantryashortcourseofnon-steroidalanti-inflammatorydrugs(NSAIDs)fortwoweeks.Asfortherangeofmotion,haveyoubeenconsistentwiththehomeexercises?"Patient:"Idothem3-4timesaweek,butit’spainful.SometimesIskipaday."Doctor:"Painisexpected,butavoidingexerciseswilldelayrecovery.Let’sadjusttheregimen:10minutesofgentlestretchingtwicedaily,followedbyquadricepsstrengthening.I’llalsoreferyoutoaphysiotherapistforsupervisedsessionstwiceaweek.Let’sscheduleafollow-upinsixweeks."3.Whatisthepatient’smainconcernduringthefollow-up?A.IncisioninfectionB.LimitedkneemobilityandswellingC.Prosthesismisalignment4.Whatdoesthedoctorrecommendfortheswelling?A.SteroidinjectionB.NSAIDsfortwoweeksC.Compressionbandage5.Whydoesthedoctoremphasizeconsistentexercises?A.TopreventbloodclotsB.ToimproverangeofmotiondespitepainC.Toreducetheriskofprosthesisloosening第二部分:阅读理解(共30分)Passage1(15分)RecentadvancesinoncologyhavehighlightedtheroleofcirculatingtumorDNA(ctDNA)inpersonalizedcancermanagement.ctDNAreferstofragmentsoftumor-derivedDNAreleasedintothebloodstream,whichcanbedetectedvialiquidbiopsy.Unliketraditionaltissuebiopsies,liquidbiopsiesareminimallyinvasiveandallowforserialmonitoringoftumormutationsasthediseaseevolves.A2024studypublishedinTheLancetOncologyenrolled500patientswithmetastaticcolorectalcancer(mCRC)toevaluatetheclinicalutilityofctDNA.ParticipantsunderwentbaselinectDNAprofilingtoidentifyactionablemutations(e.g.,KRAS,NRAS,BRAF).Treatmentwasadjustedevery8weeksbasedonctDNAclearance:patientswithundetectablectDNAcontinuedcurrenttherapy,whilethosewithpersistentoremergingmutationsswitchedtotargetedagents.ResultsshowedthatpatientswithctDNAclearancewithin16weekshadamedianprogression-freesurvival(PFS)of11.2months,comparedto5.8monthsinthosewithoutclearance(p<0.001).Additionally,35%ofpatientswhoinitiallyhadnoactionablemutationsintissuebiopsieswerefoundtohavetargetablectDNAmutations,leadingtopersonalizedtreatmentadjustments.However,challengesremain.ctDNAdetectionsensitivityvariesbycancertype—forexample,itislessreliableinearly-stagebreastcancerwheretumorburdenislow.Technicalissues,suchasfalsepositivesfromclonalhematopoiesis,alsorequirecarefulinterpretation.Despitetheselimitations,ctDNAispoisedtotransformoncologybyenablingreal-time,non-invasivemonitoringoftreatmentresponse.6.Whatisthemainadvantageofliquidbiopsyovertraditionaltissuebiopsy?A.Higheraccuracyindetectingearly-stagetumorsB.MinimallyinvasiveandallowsserialmonitoringC.Lowercostforroutinetesting7.Accordingtothe2024study,whatwasthemedianPFSforpatientswithctDNAclearancewithin16weeks?A.5.8monthsB.11.2monthsC.8.5months8.WhyweresomemCRCpatientsabletoreceivepersonalizedtreatmentadjustments?A.TheirtissuebiopsiesrevealednewmutationsB.ctDNAidentifiedtargetablemutationsnotfoundintissuesamplesC.Theyshowedrapidresponsetofirst-linechemotherapyPassage2(15分)TheWorldHealthOrganization(WHO)hasraisedconcernsovertherisingincidenceofpost-COVID-19condition(PCC),oftenreferredtoas"longCOVID."PCCisdefinedasthepersistenceofsymptomsbeyond12weeksafterinitialSARS-CoV-2infection,whichcannotbeexplainedbyanalternativediagnosis.Commonsymptomsincludefatigue,dyspnea,cognitiveimpairment("brainfog"),andmusculoskeletalpain.Amulti-centercohortstudyinvolving10,000PCCpatientsinEuropefoundthat60%reportedfatigueastheirmostdisablingsymptom,while45%hadsignificantcognitivedeficitsaffectingdailyfunctioning.Notably,20%ofpatientswithmildacuteCOVID-19(nohospitalization)developedPCC,challengingtheinitialassumptionthatseverediseaseisaprerequisite.Pathophysiologicalmechanismsarestillunderinvestigation.Hypothesesincludepersistentviralreservoirs,autoimmuneresponses(e.g.,autoantibodiestargetingendothelialcells),anddysregulatedautonomicnervoussystemfunction.ManagementofPCCismultidisciplinary:physicaltherapyforfatigue,cognitivebehavioraltherapy(CBT)forbrainfog,andpharmacologicalinterventions(e.g.,low-doseantidepressantsforneuropathicpain).TheWHOhasissuedguidelinesemphasizingpatient-centeredcare:thoroughsymptomassessment,exclusionofcomorbidities(e.g.,thyroiddysfunction),andgradualrehabilitation.PublichealtheffortsarealsofocusedoneducatinghealthcareproviderstorecognizePCCandavoiddismissingsymptomsas"psychosomatic."9.Whatisthedefinitionofpost-COVID-19conditionaccordingtothetext?A.Symptomspersistingformorethan4weeksafterinfectionB.Symptomslastingbeyond12weekswithoutalternativediagnosisC.Severerespiratoryfailurerequiringhospitalization10.Whatpercentageofnon-hospitalizedCOVID-19patientsdevelopedPCCintheEuropeanstudy?A.20%B.45%C.60%第三部分:翻译(共30分)SectionA(中译英,15分)新型冠状病毒感染后,部分患者会出现长期症状,称为“长新冠”。这些症状包括持续疲劳、运动后不适、认知障碍和睡眠障碍,严重影响生活质量。研究表明,长新冠可能与病毒残留、免疫系统异常激活或自主神经功能紊乱有关。目前,临床管理强调多学科协作,包括康复治疗、认知行为疗法和个性化药物调整,以缓解症状并帮助患者恢复正常生活。SectionB(英译中,15分)Recentstudieshavedemonstratedthatearlyinitiationofstatintherapyinpatientswithacutecoronarysyndrome(ACS)reducestheriskofrecurrentmyocardialinfarctionby25%.Thisbenefitisattributedtoboththelipid-loweringeffectandthepleiotropicactionsofstatins,suchasanti-inflammatoryandendothelialprotectiveproperties.Cliniciansarenowadvisedtoadministerhigh-intensitystatinswithin24hoursofACSpresentation,providedtherearenocontraindications(e.g.,severeliverdysfunction).Patienteducationiscrucialtoensureadherence,aslong-termstatinuseisassociatedwithimprovedsurvivaloutcomes.第四部分:写作(共20分)根据以下病例摘要,用英文撰写一份出院小结(DischargeSummary),要求包含主诉、现病史、治疗经过、出院诊断及出院医嘱(至少5条)。病例摘要:患者张芳,女,56岁,因“反复上腹痛2周,加重伴呕吐1天”入院。2周前无诱因出现上腹部胀痛,餐后明显,未重视。1天前腹痛加剧,呈持续性绞痛,伴呕吐胃内容物3次,无发热、黄疸。既往有“高血压”病史5年,规律服用氨氯地平5mgqd,血压控制可。查体:T36.8℃,P88次/分,BP130/80mmHg,腹软,上腹部压痛(+),无反跳痛,Murphy征(-)。辅助检查:血常规WBC12×10⁹/L,中性粒细胞85%;血淀粉酶580U/L(正常<125U/L);腹部CT提示胰腺肿胀,周围少量渗出。入院诊断:急性胰腺炎(轻型)。治疗:禁食、胃肠减压、奥曲肽抑制胰酶分泌、泮托拉唑护胃、头孢哌酮抗感染(过敏试验阴性)。经治疗,患者腹痛缓解,无呕吐,复查血淀粉酶降至150U/L,准予出院。答案第一部分:听力理解1.C(患者未提及高热)2.B(需等待痰培养结果)3.B(主要问题是活动受限和肿胀)4.B(建议NSAIDs两周)5.B(强调锻炼以改善活动度)第二部分:阅读理解6.B(微创且可连续监测)7.B(11.2个月)8.B(ctDNA发现组织活检未检测到的突变)9.B(症状持续12周以上且无其他诊断)10.A(20%)第三部分:翻译SectionAAfterinfectionwiththenovelcoronavirus,somepatientsdeveloplong-termsymptomsknownas"longCOVID."Thesesymptomsincludepersistentfatigue,post-exertionalmalaise,cognitiveimpairment,andsleepdisturbances,whichsignificantlyaffectqualityoflife.StudiessuggestthatlongCOVIDmayberelatedtoresidualvirus,abnormalactivationoftheimmunesystem,ordysregulationoftheautonomicnervoussystem.Currentclinicalmanagementemphasizesmultidisciplinarycollaboration,includingrehabilitationtherapy,cognitivebehavioraltherapy,andpersonalizedmedicationadjustments,toalleviatesymptomsandhelppatientsresumenormallife.SectionB近期研究表明,急性冠脉综合征(ACS)患者早期启动他汀类药物治疗可使再发心肌梗死风险降低25%。这一获益归因于他汀的降脂作用及其多效性,如抗炎和内皮保护特性。目前建议临床医生在ACS发作后24小时内给予高强度他汀治疗(无禁忌证时,如严重肝功能不全)。患者教育至关重要,以确保依从性,因为长期使用他汀与生存结局改善相关。第四部分:写作(示例)DischargeSummaryName:ZhangFang,Female,56yearsoldDateofAdmission:[具体日期]DateofDischarge:[具体日期]ChiefComplaint:Recurrentupperabdominalpainfor2weeks,aggravatedwithvomitingfor1day.HistoryofPresentIllness:Thepatientpresentedwithdullupperabdominalpain2weeksago,worseningaftermeals,whichwasinitiallyunmanaged.Onedaypriortoadmission,thepainintensifiedtopersistentcolic,accompaniedby3episodesofvomitinggastriccontents.Nofeverorjaundicewasreported.PastMedicalHistory:Hypertensionfor5years,managedwithamlodipine5mgoncedaily,bloodpressurewell-controlled.PhysicalExaminationonAdmission:T36.8℃,P88bpm,BP130/8

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