雨课堂学堂在线学堂云《Pharmaceutical Analysis（徐州医科大学）》单元测试考核答案

PharmaceuticalAnalysis第1题ThecontentofthePharmaceuticalAnalysiscourseismainlyorganizedaroundtheanalysisof()ASixcategoriesofrepresentativedrugsBEightcategoriesofrepresentativedrugsCNinecategoriesofrepresentativedrugsDSevencategoriesofrepresentativedrugs第2题GoodLaboratoryPracticeisabbreviatedas()AGMPBGSPCGLPDTLC第3题The1995editionoftheUnitedStatesPharmacopeiacorrespondsto()A20theditionB23rdeditionC21steditionD19thedition第4题TheabbreviationfortheBritishPharmacopoeiais()AGMPBBPCGLPDRP-HPLC第5题TheabbreviationfortheNationalFormularyoftheUnitedStatesis()AWHOBGMPCINNDNF第6题GMPrefersto()AGoodLaboratoryPracticeBGoodManufacturingPracticeCGoodSupplyPracticeDGoodClinicalPractice第7题Accordingtopharmaceuticalqualitystandards,thequalityofadrugisevaluatedby()AIdentification,tests,andassayBBioavailabilityCPhysicalpropertiesDPharmacologicaleffects第8题WhichorganizationpublishestheUnitedStatesPharmacopeia(USP)?AFDABUnitedStatesPharmacopeialConventionCWHODEMA第9题Whichpharmacopoeiaisabbreviatedas“JP”?ABritishPharmacopoeiaBEuropeanPharmacopoeiaCJapanesePharmacopoeiaDIndianPharmacopoeia第10题Whichguidelineprimarilyregulateslaboratoryqualitymanagement?AGoodLaboratoryPracticeBGoodManufacturingPracticeCGoodClinicalPracticeDGoodSupplyPractice第11题Whichitemisincludedinofficialdrugqualitystandards?ATherapeuticoutcomeBMarketpriceCAdvertisingapprovalDStabilitytesting第12题WhichabbreviationstandsforGoodClinicalPractice?AGLPBGMPCGCPDGSP第13题Whichpharmacopoeiaiscommonlyabbreviatedas“Ph.Eur.”?AUnitedStatesPharmacopeiaBEuropeanPharmacopoeiaCBritishPharmacopoeiaDJapanesePharmacopoeia第14题Inpharmaceuticalqualityevaluation,whichtestconfirmstheauthenticityofadrugsubstance?AIdentificationBAssayCDissolutiontestDStabilitytest第15题WhichdocumentsetsofficialdrugqualitystandardsinChina?AGMPGuidelinesBWHOTechnicalReportCChinesePharmacopoeiaDHospitalFormulary第1题Inpharmaceuticalanalysis,"heavymetals"inadrugreferto().APb²⁺BMetalionsthataffectthesafetyandstabilityofthedrugCMetalionswithlargeatomicweightsDMetallicimpuritiesthat,underspecifiedconditions,formacoloredreactionwiththioacetamideorsodiumsulfideED第2题TheVitalireactionisacharacteristicidentificationtestforwhichclassofdrugs?()ATropanealkaloidsBPhenothiazinesCAnilidesDSteroidhormones第3题Thesulfurfluorescence(thiochrome)reactionisacharacteristicidentificationreactionof().AVitaminABVitaminB1CVitaminCDVitaminE第4题Inalkalinesolution,streptomycinishydrolyzedtoformmaltol,whichreactswithFe³⁺toproducea()complex.ABlueBGreenCRedDBrown第5题Whichreagentproducesapurplecoordinationcomplexwithsalicylicacidunderweaklyacidicconditions?()AFeCl₃BHNO₃CAgNO₃DNaOH第6题Theopening-ringreactionisusedfortheidentificationofwhichclassofdrugs?()AIndoledrugsBPyridinedrugsCPhenothiazinedrugsDSteroiddrugs第7题Thesulfuricacid–fluorescencereactionisacharacteristicidentificationtestfor().AIsoniazidBNikethamideCChlorpromazineDDiazepam第8题TheGriessdiazotization–couplingreactionismainlyusedforidentificationofdrugscontaining().AAromaticprimaryaminogroupsBPhenolichydroxylgroupsCCarboxylgroupsDHeterocyclicnitrogen第9题TheFeCl₃colorreactionisbasedonthepresenceofwhichfunctionalgroupinadrugmolecule?()ACarbonylgroupBPhenolichydroxylgroupCAldehydegroupDEthergroup第10题Whichanalyticaltechniqueismainlyusedforidentificationofrawmaterialsbasedoncharacteristicabsorptionpatterns?()AUVspectrophotometryBTLCCInfraredspectroscopyDHPLC第11题Inthin-layerchromatography,whichparameterismainlyusedfordrugidentification?()APeakareaBAbsorbanceCWavelengthDRfvalue第12题TheMolischreactionismainlyusedforidentificationofdrugscontaining().AAminogroupsBCarboxylgroupsCCarbohydratesDSulfhydrylgroups第13题TheBiuretreactionischaracteristicfordrugscontaining().AAromaticringsBPeptidebondsCPhenolichydroxylgroupsDAldehydegroups第14题TheNinhydrinreactionismainlyusedforidentificationof().APrimaryaminogroupsBKetonegroupsCEstergroupsDHalogenatoms第15题TheLiebermann–Burchardreactionischaracteristicforidentificationof().AAlkaloidsBAminoglycosidesCSulfonamidesDSteroidcompoundsChapter03–PracticeQuestions第1题Whichstatementaboutpharmaceuticalqualitycontroltestsisincorrect?()APreparationstestedfordissolutiondonotrequiredisintegrationtestingBPreparationstestedforreleasedonotrequiredisintegrationtestingCPreparationstestedformeltingtimedonotrequiredisintegrationtestingDPreparationstestedforweightvariationdonotrequiredisintegrationtestingENoneofaboveiscorrect第2题AccordingtotheChinesePharmacopoeia,theweightvariationlimitfortabletswithanaverageweightbelow0.30gis().A±3%B±5%C±7.5%D±10%第3题Howmanytabletsshouldbetakenfortheweightvariationtest?()A6tabletsB10tabletsC15tabletsD20tablets第4题Contentuniformitytestingismainlyapplicableto().ALow-dosetabletsBHigh-dosetabletsCAlltabletsDPoorlysolubledrugtablets第5题Whichstatementaboutdissolutiontestingisincorrect?()ADissolutiontestingismainlyusedforpoorlysolubledrugsBDissolutiontestingincludesbasketandpaddlemethodsCThespecifiedtemperatureis37°CDDissolutionisdirectlyrelatedtoinvivobioavailability第6题WhichofthefollowingsubstancesisNOTanantioxidantusedininjections?()ASodiumsulfiteBSodiummetabisulfiteCSodiumthiosulfateDSodiumtetrathionate第7题IniodometricassayofvitaminCinjection,whichsubstanceisaddedasamaskingagenttoeliminateinterferencefromantioxidants?()AChloroformBAcetoneCEthanolDFormicacid第8题AccordingtotheChinesePharmacopoeia,whichmethodisusedforassayofferroussulfatetabletstoeliminateinterferencefromsugars?()APermanganatetitrationBCerimetrictitrationCIodometrictitrationDBromometrictitration第9题Theassayresultsofpharmaceuticalpreparationsareusuallyexpressedas().APercentagecontentBPercentageoflabeledamountCPotencyDConcentration第10题WhichtestcanbeomittedwhencontentuniformitytestingisperformedaccordingtotheChinesePharmacopoeia?()AMoisturecontentBDisintegrationtimeCWeightvariationDSolubility第11题WhichfactorisNOTincludedinpharmaceuticalstabilitytesting?()ALightBTemperatureCHumidityDpH第12题InsafetytestingofbiopharmaceuticalsaccordingtotheChinesePharmacopoeia,whichitemisNOTincluded?()APyrogentestBAbnormaltoxicitytestCHypotensivesubstancetestDResidualsolventtest第13题Chiralseparationchromatographyisabbreviatedas().ACSCBHPCECHPGCDNIRS第14题Near-infraredspectroscopyisabbreviatedas().ACSCBHPCECHPGCDNIRS第15题Inhigh-resolutiongaschromatography(HRGC),splitlessinjectionusingthesolventeffectisparticularlysuitablefor().AAnalysisofhigh-concentrationsamplesBTraceanalysisCAnalysisofthermallyunstablesamplesDAnalysisofmixtureswithsimilarcomponentconcentrationsChapter04–PracticeQuestions第1题WhichanalyticalmethodispreferredforassayofWesternmedicineactivepharmaceuticalingredients?()AVolumetricanalysisBChromatographicanalysisCSpectrophotometricanalysisDGravimetricanalysis第2题Thepurposeofidentificationtestsforactivepharmaceuticalingredientsisto().AConfirmthepurityofanunknowndrugBConfirmtheidentityofaknowndrugCEvaluatetherapeuticefficacyDDetermineimpuritycontent第3题Assayresultsofpharmaceuticalpreparationsareusuallyexpressedas().APercentagecontentBPercentageoflabeledamountCPotencyDConcentration第4题Whichtestmainlyreplacesweightvariationtestingforlow-dosetablets?()AContentuniformityBDisintegrationtimeCDissolutiontestDStabilitytest第5题WhichanalyticalitemisNOTconsideredakeyqualityattributeofactivepharmaceuticalingredients?()AIdentificationBAssayCImpurityprofileDTherapeuticeffect第6题WhichfactorisNOTincludedinpharmaceuticalstabilitytesting?()ALightBTemperatureCHumidityDpH第7题Whichtestismainlyappliedtoensuredoseconsistencyamongindividualdosageunits?()AContentuniformityBDissolutiontestCDisintegrationtestDStabilitytest第8题Dissolutiontestingismainlyappliedtowhichtypeofdosageforms?()AParenteralpreparationsBLiquidpreparationsCSolidoraldosageformsDSemi-solidpreparations第9题Whichanalyticalitemdirectlyreflectstheinvitroreleasebehaviorofsoliddosageforms?()AWeightvariationBContentuniformityCDisintegrationtimeDDissolutiontest第10题TheabbreviationfortheNationalFormularyoftheUnitedStatesis()AWHOBGMPCINNDNF第11题GMPrefersto()AGoodLaboratoryPracticeBGoodManufacturingPracticeCGoodSupplyPracticeDGoodClinicalPractice第12题TheFeCl₃colorreactionisbasedonthepresenceofwhichfunctionalgroupinadrugmolecule?()ACarbonylgroupBPhenolichydroxylgroupCAldehydegroupDEthergroup第13题Whichanalyticaltechniqueismainlyusedforidentificationofrawmaterialsbasedoncharacteristicabsorptionpatterns?()AUVspectrophotometryBTLCCInfraredspectroscopyDHPLC第14题Inthin-layerchromatography,whichparameterismainlyusedfordrugidentification?()APeakareaBAbsorbanceCWavelengthDRfvalue第15题WhichtestcanbeomittedwhencontentuniformitytestingisperformedaccordingtotheChinesePharmacopoeia?()AMoisturecontentBDisintegrationtimeCWeightvariationDSolubilityChapter05–PracticeQuestions第1题WhichfactorisNOTincludedamongthegeneralinfluencingfactorsinpharmaceuticalstabilitytesting?()ALightBHightemperatureCHighhumidityDpHED第2题Themainpurposeofaddingastabilizerduringformulationofaspirincompoundtabletsisto().APromotedrugdissolutionBPreventhydrolysisCImprovetasteDIncreasetablethardness第3题WhichoperationhelpstomaintainstabilityduringiodometricassayofvitaminCinjection?()AUsingchloroformBAddingacetoneCAddingethanolDLoweringtemperature第4题Inpharmaceuticalstabilitystudies,exposuretowhichfactormainlycausesphotodegradation?()ALightBHeatCHumidityDOxygen第5题Whichtestitemdirectlyreflectstheinvitrostabilityofsolidoraldosageformsduringstorage?()AWeightvariationBContentuniformityCDisintegrationtimeDDissolutiontest第6题Thetechniquereferredtoastandemmassspectrometryis().AMs/MsBNMRCRIADBP第7题Thetechniqueknownasnuclearmagneticresonanceis().AMs/MsBNMRCRIADBP第8题Thetechniquereferredtoasradioimmunoassayis().AMs/MsBNMRCRIADBP第9题High-performancecapillaryelectrophoresisisabbreviatedas().ACSCBHPCECHPGCDNIRS第10题High-resolutiongaschromatographyisabbreviatedas().ACSCBHPCECHPGCDNIRS第11题Whichofthefollowingstatementsaboutdosageformtestingrequirementsisincorrect?().ADosageformsrequiringsolubilitytestingdonotrequiredisintegrationtestingBDosageformsrequiringdissolutiontestingdonotrequiredisintegrationtestingCDosageformsrequiringmeltingorsofteningtimetestingdonotrequiredisintegrationtestingDDosageformsrequiringweightvariationtestingdonotrequiredisintegrationtesting第12题Contentuniformitytestingismainlyintendedfor().ALow-dosetabletsBHigh-dosetabletsCAlltabletsDPoorlysolubledrugtablets第13题Indosageformanalysis,assayresultsareexpressedas().APercentagecontentBPercentageoflabeledamountCPotencyDConcentration第14题AccordingtotheChinesePharmacopoeia,ifcontentuniformityistested,whichtestmaybeomitted?().AWatercontentBDisintegrationtimeCWeightvariationDSolubility第15题AccordingtotheChinesePharmacopoeia,whichmethodisusedforthedeterminationofalcoholcontent?().AGaschromatography(GC)BHPLCCTLCDUVspectrophotometryChapter06–PracticeQuestions第1题Whichparameterevaluatestheclosenessbetweenmeasuredvaluesandthetruevalueinanalyticalmethodvalidation?()APrecisionBAccuracyCSpecificityDLinearityED第2题Whichvalidationparameterassessestheabilityofananalyticalmethodtoremainunaffectedbysmallvariations?()AAccuracyBRepeatabilityCRobustnessDSensitivity第3题Linearityinmethodvalidationreferstothe().ARelationshipbetweenresponseandconcentrationBReproducibilityofresultsCDetectioncapabilityDMethodprecision第4题Toensuredrugquality,strictinspectionmustbecarriedout,andinspectionworkshouldfollow().APharmaceuticalanalysisBNationalPharmacopoeiaCPhysicalandChemicalHandbookDLocalstandards第5题ThefirsteditionoftheChinesePharmacopoeiaafterthefoundingofthePeople’sRepublicofChinawaspublishedin().A1951B1950C1952D1953第6题Uptonow,howmanyeditionsoftheChinesePharmacopoeiahavebeenpublished?().AEightBFiveCSevenDSix第7题Thepurposeofidentificationtestsofdrugsistoprovetheauthenticityof().AUnknowndrugsBKnowndrugsCThetherapeuticefficacyofknowndrugsDThepurityofunknowndrugs第8题Fortheassayofchemicaldrugsubstances,thefirst-choiceanalyticalmethodis().AVolumetricanalysisBChromatographicmethodsCSpectrophotometricmethodsDGravimetricanalysis第9题WhichofthefollowingisNOTincludedamongfactorsaffectingdrugefficacytesting?().ACrystalfinenessandcrystalformBContentuniformityCDilutionDAcidity第10题SincethefoundingofthePRC,howmanyeditionsoftheChinesePharmacopoeiahavebeenpublished?().AFiveBSixCSevenDEight第11题Apartfromgeneralrequirements,whichofthefollowingisNOTaninfluencingfactorindrugstabilitytesting?().AStronglightBHightemperatureCHighhumidityDpH第12题AccordingtotheGeneralNoticesoftheChinesePharmacopoeia,the“Tests”sectionincludes().AContentuniformityoftabletsBClinicalefficacyofdrugsCPurityrequirementsofdrugsDSafety第13题ThecontentsofChinesedrugqualitystandardsdoNOTinclude().ANameBDescriptionCIdentificationDManufacturingprocess第14题IntherefractiveindexnotationnᵗspecifiedintheChinesePharmacopoeia,trefersto().A10°CB20°CC25°CD0°C第15题Whichofthefollowingstatementsaboutdosageformtestingrequirementsisincorrect?().ADosageformsrequiringsolubilitytestingdonotrequiredisintegrationtestingBDosageformsrequiringdissolutiontestingdonotrequiredisintegrationtestingCDosageformsrequiringmeltingorsofteningtimetestingdonotrequiredisintegrationtestingDDosageformsrequiringweightvariationtestingdonotrequiredisintegrationtestingChapter07–PracticeQuestions第1题Whichparameterevaluatestheclosenessbetweenmeasuredvaluesandthetruevalueinanalyticalmethodvalidation?()APrecisionBAccuracyCSpecificityDLinearityED第2题Whichvalidationparameterassessestheabilityofananalyticalmethodtoremainunaffectedbysmallvariations?()AAccuracyBRepeatabilityCRobustnessDSensitivity第3题Linearityinmethodvalidationreferstothe().ARelationshipbetweenresponseandconcentrationBReproducibilityofresultsCDetectioncapabilityDMethodprecision第4题AccordingtotheChinesePharmacopoeia,thepyrogentestforbiochemicaldrugsisperformedusing().ARabbittestBLimulusamebocytelysate(LAL)testCBothmethodsareusedDNeithermethodisused第5题AccordingtotheChinesePharmacopoeia,whichofthefollowingisNOTincludedinthesafetytestsforbiochemicaldrugs().APyrogentestBAbnormaltoxicitytestCTestforhypotensivesubstancesDResidualsolventtest第6题WhichofthefollowingisNOTafactoraffectingenzymaticreactions().ASubstrateconcentrationBpHandtemperatureCMetalionsDReactiontime第7题Electrophoreticmethodsaresuitablefortheanalysisofwhichtypeofdrugs().AChargedionsBNeutralionsCAcidicionsDBasicions第8题Radioimmunoassayrefersto().AMs/MsBNMRCRIADBP第9题IniodometricassayofvitaminCinjection,whichsubstanceisaddedasamaskingagenttoeliminateinterferencefromantioxidants?()AChloroformBAcetoneCEthanolDFormicacid第10题AccordingtotheChinesePharmacopoeia,whichmethodisusedforassayofferroussulfatetabletstoeliminateinterferencefromsugars?()APermanganatetitrationBCerimetrictitrationCIodometrictitrationDBromometrictitration第11题Theassayresultsofpharmaceuticalpreparationsareusuallyexpressedas().APercentagecontentBPercentageoflabeledamountCPotencyDConcentration第12题WhichtestcanbeomittedwhencontentuniformitytestingisperformedaccordingtotheChinesePharmacopoeia?()AMoisturecontentBDisintegrationtimeCWeightvariationDSolubility第13题WhichfactorisNOTincludedinpharmaceuticalstabilitytesting?()ALightBTemperatureCHumidityDpH第14题InsafetytestingofbiopharmaceuticalsaccordingtotheChinesePharmacopoeia,whichitemisNOTincluded?()APyrogentestBAbnormaltoxicitytestCHypotensivesubstancetestDResidualsolventtest第15题WhichofthefollowingsubstancesisNOTanantioxidantusedininjections?()ASodiumsulfiteBSodiummetabisulfiteCSodiumthiosulfateDSodiumtetrathionateChapter08–PracticeQuestions第1题Whichfunctionalgroupischaracteristicofaromaticaciddrugs?()AHydroxylBAminoCCarboxylDEsterED第2题Whichreactioniscommonlyusedforidentificationofsalicylicacid?()ASilvermirrortestBFerricchloridereactionCDiazotizationDOxidation第3题Theacidityofaromaticaciddrugsmainlyoriginatesfromthe().AAromaticringBEsterlinkageCPhenylgroupDCarboxylgroup第4题WhichofthefollowingisNOTincludedamongfactorsaffectingdrugefficacytesting?().ACrystalfinenessandcrystalformBContentuniformityCDilutionDAcidity第5题SincethefoundingofthePRC,howmanyeditionsoftheChinesePharmacopoeiahavebeenpublished?().AFiveBSixCSevenDEight第6题Apartfromgeneralrequirements,whichofthefollowingisNOTaninfluencingfactorindrugstabilitytesting?().AStronglightBHightemperatureCHighhumidityDpH第7题AccordingtotheGeneralNoticesoftheChinesePharmacopoeia,the“Tests”sectionincludes().AContentuniformityoftabletsBClinicalefficacyofdrugsCPurityrequirementsofdrugsDSafety第8题ThecontentsofChinesedrugqualitystandardsdoNOTinclude().ANameBDescriptionCIdentificationDManufacturingprocess第9题IntherefractiveindexnotationnᵗspecifiedintheChinesePharmacopoeia,trefersto().A10°CB20°CC25°CD0°C第10题Whichofthefollowingstatementsaboutdosageformtestingrequirementsisincorrect?().ADosageformsrequiringsolubilitytestingdonotrequiredisintegrationtestingBDosageformsrequiringdissolutiontestingdonotrequiredisintegrationtestingCDosageformsrequiringmeltingorsofteningtimetestingdonotrequiredisintegrationtestingDDosageformsrequiringweightvariationtestingdonotrequiredisintegrationtesting第11题Contentuniformitytestingismainlyintendedfor().ALow-dosetabletsBHigh-dosetabletsCAlltabletsDPoorlysolubledrugtablets第12题Indosageformanalysis,assayresultsareexpressedas().APercentagecontentBPercentageoflabeledamountCPotencyDConcentration第13题AccordingtotheChinesePharmacopoeia,ifcontentuniformityistested,whichtestmaybeomitted?().AWatercontentBDisintegrationtimeCWeightvariationDSolubility第14题AccordingtotheChinesePharmacopoeia,whichmethodisusedforthedeterminationofalcoholcontent?().AGaschromatography(GC)BHPLCCTLCDUVspectrophotometry第15题AccordingtotheChinesePharmacopoeia,whichmethodisusedforpyrogentestingofbiochemicaldrugs?().ARabbittestBLimulusamebocytelysate(LAL)testCBothDNeitherChapter09–PracticeQuestions第1题Phenethylaminedrugstypicallyexhibitwhichchemicalproperty?()ABasicityBAcidityCNeutralityDOxidizingabilityED第2题Whichanalyticalmethodiscommonlyusedforphenethylaminedrugidentification?()ATitrationBOxidationCDiazotizationDComplexation第3题Themajorfunctionalgroupresponsibleforbioactivityofphenethylaminedrugsisthe().AHydroxylBEthylamineCEsterDCarbonyl第4题Inpharmaceuticalanalysis,"heavymetals"inadrugreferto().APb²⁺BMetalionsthataffectthesafetyandstabilityofthedrugCMetalionswithlargeatomicweightsDMetallicimpuritiesthat,underspecifiedconditions,formacoloredreactionwiththioacetamideorsodiumsulfide第5题TheVitalireactionisacharacteristicidentificationtestforwhichclassofdrugs?()ATropanealkaloidsBPhenothiazinesCAnilidesDSteroidhormones第6题Thesulfurfluorescence(thiochrome)reactionisacharacteristicidentificationreactionof().AVitaminABVitaminB1CVitaminCDVitaminE第7题Inalkalinesolution,streptomycinishydrolyzedtoformmaltol,whichreactswithFe³⁺toproducea()complex.ABlueBGreenCRedDBrown第8题Whichreagentproducesapurplecoordinationcomplexwithsalicylicacidunderweaklyacidicconditions?()AFeCl₃BHNO₃CAgNO₃DNaOH第9题Theopening-ringreactionisusedfortheidentificationofwhichclassofdrugs?()AIndoledrugsBPyridinedrugsCPhenothiazinedrugsDSteroiddrugs第10题Thesulfuricacid–fluorescencereactionisacharacteristicidentificationtestfor().AIsoniazidBNikethamideCChlorpromazineDDiazepam第11题TheGriessdiazotization–couplingreactionismainlyusedforidentificationofdrugscontaining().AAromaticprimaryaminogroupsBPhenolichydroxylgroupsCCarboxylgroupsDHeterocyclicnitrogen第12题TheFeCl₃colorreactionisbasedonthepresenceofwhichfunctionalgroupinadrugmolecule?()ACarbonylgroupBPhenolichydroxylgroupCAldehydegroupDEthergroup第13题Whichanalyticaltechniqueismainlyusedforidentificationofrawmaterialsbasedoncharacteristicabsorptionpatterns?()AUVspectrophotometryBTLCCInfraredspectroscopyDHPLC第14题Inthin-layerchromatography,whichparameterismainlyusedfordrugidentification?()APeakareaBAbsorbanceCWavelengthDRfvalue第15题WhichfactorisNOTincludedinpharmaceuticalstabilitytesting?()ALightBTemperatureCHumidityDpHChapter10–PracticeQuestions第1题Para-aminobenzoateesterdrugsarestructurallyclassifiedas().AAmidesBAlkaloidsCHeterocyclesDEstersED第2题Whichreactionischaracteristicforidentificationofpara-aminobenzoateesterdrugs?()ADiazotizationcouplingBOxidationCReductionDHydrolysis第3题Theesterbondinpara-aminobenzoatedrugsisproneto().AOxidationBReductionCHydrolysisDIsomerization第4题Para-aminobenzoateesterdrugsaremainlyusedas().ALocalanestheticsBAntibioticsCAntiviralsDAntipyretics第5题Thearomaticprimaryaminogroupinpara-aminobenzoateesterscanundergo()reaction.ADiels–AlderBDiazotizationCEsterificationDPolymerization第6题Theesterbondinpara-aminobenzoatedrugsismostsusceptibleto()underalkalineconditions.AOxidationBReductionCHydrolysisDNitration第7题Afterhydrolysisofpara-aminobenzoateesters,theproductformedis().AAmideBKetoneCAldehydeDPara-aminobenzoicacid第8题TheUVabsorptionofpara-aminobenzoateesterdrugsismainlydueto().AAminogroupBConjugatedaromaticringCEsterlinkageDAlkylchain第9题InTLCidentificationofpara-aminobenzoateesters,themainparameterusedis().AAbsorbanceBWavelengthCPeakareaDRfvalue第10题Underacidicconditions,theaminogroupofpara-aminobenzoateesterstendsto().AOxidizeBReduceCProtonateDHydrolyze第11题Thecolorformedindiazotization–couplingreactionofpara-aminobenzoateestersisusually().AColoredazodyeBColorlessCWhiteprecipitateDGreensolution第12题Themainanalyticalmethodforassayofpara-aminobenzoateesterdrugsintabletsis().ATitrationBHPLCCGravimetryDPolarimetry第13题Whichfunctionalgroupisresponsibleforesterhydrolysisinpara-aminobenzoatedrugs?()AAminogroupBAromaticringCCarbonylgroupDEstergroup第14题Whichconditionaccelerateshydrolysisofpara-aminobenzoateesterdrugs?()ALowtemperatureBNeutralwaterCAlkalinesolutionDDryair第15题Thediazotizationreactionofpara-aminobenzoateestersrequireswhichcondition?()AStrongalkalinemediumBAcidicmediumatlowtemperatureCHightemperatureDOrganicsolventChapter11–PracticeQuestions第1题Anilidedrugsarecharacterizedbythepresenceofwhichfunctionalgroup?()AEsterBAmideCAminoDCarboxylED第2题Whichanalyticalmethodiscommonlyusedforanilidedrugcontentdetermination?()ATLCBGCCTitrationDUVspectrophotometry第3题Thehydrolysisofanilidedrugsmainlyyields().AAromaticaminesandacidsBAlcoholsCKetonesDEthers第4题Anilidedrugsbelongstructurallytowhichclassofcompounds?AEstersBAlkaloidsCAromaticamidesDEthers第5题Thecharacteristicfunctionalgroupinanilidedrugsisthe().ACarbonylgroupBAmidebondCHydroxylgroupDNitrogroup第6题Understrongacidicconditions,anilidedrugsmainlyundergo().AHydrolysisBOxidationCReductionDNitration第7题Afterhydrolysis,anilidedrugsproducewhichcompound?AAlcoholsBKetonesCEstersDAromaticamines第8题TheUVabsorptionofanilidedrugsismainlydueto().AAlkylchainBEtherlinkageCAromaticconjugationDAmmoniumsalt第9题Whichreagentiscommonlyusedtoidentifyaromaticaminesformedafterhydrolysisofanilides?ASodiumnitriteBFerricchlorideCSilvernitrateDPotassiumiodide第10题TheFeCl₃colorreactionisgenerallynegativeforintactanilidedrugsbecausetheylack().AAmidegroupsBPhenolichydroxylgroupsCAromaticringsDAminogroups第11题Whichanalyticaltechniqueiswidelyusedforquantitativedeterminationofanilidedrugs?ATLCBPolarimetryCGravimetryDHPLC第12题Thehydrolysisrateofanilidedrugsincreasesunder().ALowtemperatureBNeutralconditionsCHightemperatureDDrystorage第13题InTLCanalysisofanilidedrugs,identificationismainlybasedon().ARfvalueBPeakheightCAbsorbanceDConductivity第14题AnilidedrugsmayshowUVabsorptionmaximatypicallyinwhichregion?AVisibleregionBUltravioletregionCInfraredregionDMicrowaveregion第15题Thestabilityofanilidedrugsismainlyaffectedby().ALightonlyBOxygenonlyCPressureDMoistureChapter12–PracticeQuestions第1题Dihydropyridinecalciumchannelblockerssharewhichbasicstructuralskeleton?()APhenyl-1,4-dihydropyridinenucleusBPyridinenucleusCIndolenucleusDQuinolinenucleusED第2题Thereducingpropertyofdihydropyridinedrugsismainlyattributedtowhichstructuralfeature?()AThedihydropyridineringBNitrogrouponthebenzeneringCEstersidechainsDChiralcarbonatC4第3题Dihydropyridinedrugsareextremelyunstableunderwhichconditionandthereforeshouldbeprotectedduringanalysis?()AHighhumidityBLightexposureCHeatDAcidicconditions第4题Intheidentificationtestusingsodiumhydroxide