急性热病性多神经炎神经病学双语课件

case nMale,35years old,complained of weakness of four limbs for 1 day on admission.He had a cold 2 weeks before admission.the weakness became severe and lead to tetraplegia on the 3 day.Aphagia appeared almost the same time.Numbness of fingers and toes was mentioned.He had no difficulties on micturation. exam nCranial nerves:diminished elevation of palatal,gag reflex disappear nMotor system:muscle tension decreased; muscle force: 0 grade of all four limbs. nSensory system:slightly stocking-glove type pain decreased. nReflex:areflexia.Babinskis sign:(-). nOthers:normal. Acute Inflammatory Demyelinating Polyneuropathy Guillain-Barre Syndrome zhao dongxue Etiology and Pathology Etiology: unknown. cell-mediated immunologic reaction Pathology: Perivascular lymphocytic infiltrates Perivenous segmental demyelinating Clinical Features(I) nPreceding infection: nMotor system:weakness of limbs symmetic and flaccid respiratory failure Clinical Features(II) nSensory system: stocking-glove type Clinical Features(III) Cranial nerves:facial diplegia. bulbar palsy others. Autonomic dysfunction:tachycardia labile blood pressure disturbed sweating Sphincter function:not involved usually Laboratory Findings nCSF:protein-cell dissociation on the third week nElectrophysiology:MCV and SCV slowed Diagnosis nPreceding Infection nClinical Features nLaboratory Findings Differential Diagnosis nPeriodic paralysis nPoliomyelitis nMyasthenia Gravis Treatment nSymptomatic Treatmeat: n