组织学skinppt课件

SkinandSkinAppendages constitution epidermisdermisfunction protectionsensoryregulationsecretionabsorptionthickskin thinskin skin largestorgan I Epidermiskeratinizedstratifiedsquamousepitheliumconsistof5layerskeratinocytes nonkeratinocytes Photomicrographofasectionofthickskin Notethebloodvesselsinthedermalpapillaeimprovingthenutritionofthethickepithelium Picrosirius hematoxylinstain Mediummagnification Photomicrographofasectionofthinskin Thestratumcorneumisthinnerthanthatinthickskin 1 StratumbasaleLM asinglelayerofbasophiliccolumar cuboidalcells restonBMEM ribosome keratinfilaments desmosomeandhemidesmosomeStemcell mitoticactivity 2 StratumspinosumLM 5 10layers polygonalspinousprocessesEM bundledK F LM Tonofilaments lamellargranulesdesmosomes Stratumspinosumoftheskinfromthesoleofthefoot thickskin showingthespinyprojectionsthatstronglybindthecellsofthislayertogethertoresistabrasion Pararosaniline toluidinebluestain Mediummagnification 3 StratumgranulosumLM 3 5layers spindle basophilicEM Keratohyalingranules basophilic nomembrane containngprotein AbundantL G excreteintointer cellularspacetostrengthenthecellconnection thickenthecellmembrane 4 Stratumlucidum 3 4layersofcellappeareosinophilicandtransparent nonucleusandorganella denselypackedkeratinfilaments 5 Stratumcorneum eosinophilichornycell filledwithKeratinnodesmosome continuousshed Cell Cell CytoplasmCellMorph Junc R LG Tf KhG KMemb lle Nu1LayerDes S ColumHemi Scat BasoPhil D SteredNormalNormal5 10LPolygonalD S Basophil BundlesNormalNormal3 5LSpindleD S ThickerDege BasophilBundlesExo nerating cytosisFlat D S MoreDis Acidophil thickappearNumerousLFlat Disap PackedwithkeratinMore AcidophilpearingThick LG lamellatedg Tf tonofibrilKhG keratohyling K keratin Non keratinocytes1 Melanocyte2 Langerhanscell3 Merkelcell 1 Melanocytedistributionsctteredinstratumbasalecharacteristic roundbodywithlongproceses nodesmosomewithkeratinocytes melanosome tyrosine melanin melaningranules keratinocytesFuntion protectskinfromultravioletradiation determineskincolor 2 LangerhanscellOrigin bonemarrow derivedDistribution stratumspinosumCharacteristic star shaped Birbeckgranules nodesmosomeFunction identify bind processantigen MPS 3 Merkel scellDistribution stratumbasaleCharacteristics shortprocesses densegranulesincytoplasm synapsesbetweenthebaseofthecellsandnerveendingsFuntion mayserveassensorymechanoreceptors II DermisBelowepidermisFormedbydenseconnectivetissue 1 Papillarylayerdermalpapillaec t w finecollagenousf morecells capillaries freenerveendingsMeissner scorpuscles2 ReticularlayerDensec t fewercells bundledcollagenousf moreelasticf appendagesofskinPaciniancorpuscles tactilecorpuscle Meissner IV AppendagesofskinHairsSebaceousglandsSweatglandsNails III SubcutaneoustissueFormedbylooseconnectivetissueandadiposetissue origin Hairsareelongatedkeratinizedstructuresderivedfrominvaginationsofepidermalepithelium 1 Hair HairshaftHairrootHairfollicleHairbulbHairpapilla Arrectorpilimuscle obliquedirection fairfollicletothepapillarylayerofthedermisarebundlesofsmoothmusclecells betweenhairfollicleandarrectorpiliopenintoupperportionofhairfollicleSoftenskinandkillbacteria regulatedbysexhormorebegintofunctionatpuberty sebum 2 Sebaceousglands 3 Sweatgland 1 Merocr