CVS常用药物概论ppt课件

1、CONTRACTILITYHEART RATERhythmPRELOADAFTERLOADL/MinCARDIACOUTPUT(CI=CO/m)NE E ISOSelecting inotropic and vasopressor agents for specific hemodynamic disturbances in childrenHemodynamic patternNormalDeceasedElevatedBlood pressure or SVRMyocardial dysfunction Dobutamine or dopamineor amrinoneEpinephrin

2、e or dopamine(or dobutamine plusnorepinephrine)DobutamineplusnitroprussideCHFDobutamine PrimacorDopamineDobutamineplusnitroprussideBradycardiaNoneIsoproterenolNoneElectrolytesnuseful for both inotropy and vasoconstrictionnincrease SVR, and may decrease CO by increasing afterloadnInotropic, vasodilat

3、or and lusotropic effectrequirementtitratable action.Selecting inotropic and vasopressor agents for specific hemodynamic disturbances in childrenHemodynamic patternNormalDeceasedElevatedBlood pressure or SVRSeptic Shock Stroke index High Stroke Index low to NNone or dopamineDobutamine or dopamineNor

4、epinephrineDopamine or epinephrine(or dobutamine plusnorephinephrine)NoneDobutamineplusnitroprussideCardiogenic shockDobutamine or amrinoneor dopamineEpinephrine or dopamine-Myocardial dysfunction Dobutamine or dopamineor amrinoneEpinephrine or dopamine(or dobutamine plusnorepinephrine)Dobutamineplu

5、snitroprussideCHFDobutamine or dopamineor amrinone-DobutamineplusnitroprussideBradycardiaNoneIsoproterenolNoneDRIP FORMULA:6 X WT. IN KG X MCG/KG/MIN = mg in 100 ml of D5W/NSML/HRAlso another way to calculate is:ISOPROTERENOLEPINEPHRINENOREPRINEPHRINE0.6 X BODY WT. IN KG = _ MG IN 100ML 1 ML/HR WILL DELIVER 0.1 MCG/KG/MINDOPAMINEDOBUTAMINEAMRINONE