牙体牙髓病用药课件

牙体牙髓病用药 刘萍 天津医科大学口腔医学院 WuhanWuhan University School of University School of StomatologyStomatology WuhanWuhan University School of University School of StomatologyStomatology 特 点 系统治疗 局部用药 WuhanWuhan University School of University School of StomatologyStomatology 防龋药物 抗牙本质敏感症药物 牙漂白药物 盖髓术药物 活髓切断术药物 根管治疗药物 其他药物 内 容 WuhanWuhan University School of University School of StomatologyStomatology 一、防龋药物 2%氟化钠 8%氟化亚锡 1.23%的酸性氟磷酸盐 Approved by Approved by FDAFDA, March 28,1980, March 28,1980 WuhanWuhan University School of University School of StomatologyStomatology 处方组成 氟化钠: 2%, 溶液 氟化亚锡：8%，溶液和凝胶 酸性磷酸氟：1.23%， 溶液和凝胶 WuhanWuhan University School of University School of StomatologyStomatology 药理作用 降低釉质的溶解度 促进釉质再矿化 对口腔细菌的影响 WuhanWuhan University School of University School of StomatologyStomatology 临床应用 F 全身应用 F 局部应用 含漱 涂搽 氟化钠片剂，1mg/d WuhanWuhan University School of University School of StomatologyStomatology 二、抗牙本质敏感症药物 硝酸钾 potassium nitrate 氟化钠甘油 sodium glycerine fluoride 草酸钾 potassium oxalate 复合脱敏剂 WuhanWuhan University School of University School of StomatologyStomatology 处方组成 WuhanWuhan University School of University School of StomatologyStomatology WuhanWuhan University School of University School of StomatologyStomatology 药理作用 阻塞牙本质小管 减少牙髓神经敏感性 WuhanWuhan University School of University School of StomatologyStomatology WuhanWuhan University School of University School of StomatologyStomatology 临床应用 F 局部应用 WuhanWuhan University School of University School of StomatologyStomatology Ultra EZ WuhanWuhan University School of University School of StomatologyStomatology 三、牙漂白药物 过氧化氢 hydrogen peroxide 过氧化脲 carbamide peroxide 过硼酸钠 sodium perborate WuhanWuhan University School of University School of StomatologyStomatology 处方组成 过氧化氢：35%，溶液/凝胶 过氧化脲：10%，15%，20% 凝胶 过硼酸钠：糊剂 WuhanWuhan University School of University School of StomatologyStomatology Opalescience (Ultradent) WuhanWuhan University School of University School of StomatologyStomatology 药理作用 氧化还原反应 WuhanWuhan University School of University School of StomatologyStomatology 临床应用活髓牙漂白 F诊室内漂白 in-office bleaching F家庭内漂白 in-home bleaching WuhanWuhan University School of University School of StomatologyStomatology In-home bleaching WuhanWuhan University School of University School of StomatologyStomatology In-home bleaching WuhanWuhan University School of University School of StomatologyStomatology WuhanWuhan University School of University School of StomatologyStomatology 临床应用无髓牙漂白 F 髓腔内漂白 WuhanWuhan University School of University School of StomatologyStomatology 髓腔内漂白 WuhanWuhan University School of University School of StomatologyStomatology 四、盖髓术药物 氢氧化钙 calcium hydroxide 氧化锌丁香油 zinc oxide eugenol WuhanWuhan University School of University School of StomatologyStomatology 处方组成 氢氧化钙 赋形剂 其他添加剂 WuhanWuhan University School of University School of StomatologyStomatology 赋形剂的要求 理想赋形剂： 1.能逐渐缓慢释放钙离子和羟基 离子 2.能允许氢氧化钙在组织内缓慢扩 散 在组织液中的溶解度低 3.对氢氧化钙的药理作用没有影响 WuhanWuhan University School of University School of StomatologyStomatology 赋形剂种类 水性赋形剂： 无菌水、蒸馏水、无菌蒸馏水、 双蒸水、生理盐水、林格液等 WuhanWuhan University School of University School of StomatologyStomatology 赋形剂种类 粘性赋形剂： 甘油、聚乙二醇、丙二醇等 WuhanWuhan University School of University School of StomatologyStomatology Dycal (Dentsply) WuhanWuhan University School of University School of StomatologyStomatology 赋形剂种类 油性赋形剂： 橄榄油 樟脑对氯酚CMCP 醋酸间甲酚酯 WuhanWuhan University School of University School of StomatologyStomatology 药理作用 抗菌作用 诱导矿化组织形成修复性牙本质 WuhanWuhan University School of University School of StomatologyStomatology WuhanWuhan University School of University School of StomatologyStomatology 临床应用 F直接盖髓术：氢氧化钙糊剂 WuhanWuhan University School of University School of StomatologyStomatology F 间接盖髓术： 氢氧化钙糊剂 氧化锌丁香油糊剂 WuhanWuhan University School of University School of StomatologyStomatology 五、活髓切断术药物 甲醛甲酚溶液 formcresol（FC） 戊二醛 glutaraldehyde 仅用于乳牙 ！ WuhanWuhan University School of University School of StomatologyStomatology 六、根管治疗术药物 qq 根管冲洗剂根管冲洗剂 qq 根管消毒剂根管消毒剂 WuhanWuhan University School of University School of StomatologyStomatology q 根管冲洗剂 次氯酸钠 sodium hypochloride 过氧化氢 hydrogen peroxide 乙二胺四乙酸钠 ethylenediaminetetraacetic acid （EDTA） WuhanWuhan University School of University School of StomatologyStomatology q 根管消毒剂 氢氧化钙氢氧化钙 calcium hydroxidecalcium hydroxide 碘仿碘仿 Iodoform Iodoform WuhanWuhan University School of University School of StomatologyStomatology Calcium Hydroxide Plus Point WuhanWuhan University School of University School of StomatologyStomatology 药理作用抗菌 细菌细胞膜损伤 细菌蛋白质变性 细菌DNA损伤 灭活细菌LPS WuhanWuhan University School of University School of StomatologyStomatology WuhanWuhan University School of University School of StomatologyStomatology WuhanWuhan University School of University School of StomatologyStomatology WuhanWuhan