Melperone-DataSheet-生命科学试剂-MedChemExpress

1、Hotline: 400-820-3792Inhibitors Agonists Screening Librarieswww.MedChemEMelperoneCat. No.: HY-B2169CAS No.: 3575-80-2分式: CHFNO分量: 263.35作靶点: Others作通路: Others储存式: Powder -20C 3 years4C 2 yearsIn solvent -80C 6 months-20C 1 month溶解性数据体外实验 DMSO : 41.67 mg/mL (158.23 mM; Need ultrasonic)Mass Solvent1 m

2、g 5 mg 10 mg Concentration制备储备液1 mM 3.7972 mL 18.9861 mL 37.9723 mL5 mM 0.7594 mL 3.7972 mL 7.5945 mL10 mM 0.3797 mL 1.8986 mL 3.7972 mL请根据产品在不同溶剂中的溶解度，选择合适的溶剂配制储备液，并请注意储备液的保存式和期限。体内实验 请根据您的实验动物和给药式选择适当的溶解案，配制前请先配制澄清的储备液，再依次添加助溶剂(为保证实验结果的可靠性，体内实验的作液，建议您现现配，当天使；澄清的储备液可以根据储存条件，适当保存；以下溶剂前的百分 指该溶剂在您配制终溶

3、液中的体积占)：1. 请依序添加每种溶剂： 10% DMSO 40% PEG300 5% Tween-80 45% salineSolubility: 2.08 mg/mL (7.90 mM); Clear solution2. 请依序添加每种溶剂： 10% DMSO 90% (20% SBE-CD in saline)Solubility: 2.08 mg/mL (7.90 mM); Clear solution3. 请依序添加每种溶剂： 10% DMSO 90% corn oilSolubility: 2.08 mg/mL (7.90 mM); Clear solution1/2 Mast

4、er of Small Molecules 您边的抑制剂师www.MedChemEBIOLOGICAL ACTIVITY物活性 Melperone种丁酰苯，种于睡眠诱导的抗精神病药物，常于治疗精神病。 Melperone 于各种适应症，包括精神分裂症的治疗，以及年的躁动。REFERENCES1. Hefner G, et al. Melperone but not bisoprolol or metoprolol is a clinically relevant inhibitor of CYP2D6: evidence from a therapeutic drugmonitoring su

5、rvey. J Neural Transm (Vienna). 2015 Nov;122(11):1609-17.2. Bobo WV, et al. Melperone, an aytpical antipsychotic drug with clozapine-like effect on plasma prolactin: contrast with typicalneuroleptics. Hum Psychopharmacol. 2009 Jul;24(5):415-22.McePdfHeightCaution: Product has not been fully validated for medical applications.For research use only.Tel: 400-820-3792; 021-58